Biyomühendislik: Güncel gönderi
Toplam kayıt 76, listelenen: 41-60
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Aptamer Temelli Afinite Kromatografisiyle Protein C Saflaştırılmasının Araştırılması
(Fen Bilimleri Enstitüsü, 2021-12-30)Protein C (PC) is a vitamin K-dependent plasma protein. Activated Protein C (APC) is a glycoprotein derived from protein C. It is formed by cleavage of an activation peptide by the thrombin-linked thrombomodulin (T-TM) ... -
Nanotopografik Fiber Matrikslerin Doku İskelesi Olarak Üretimi ve İn-Vitro Etkinliklerinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2022)This study was funded by Hacettepe University Scientific Research Projects Coordination Unit (BAP) graduate project entitled "Production Of Nanotopographic Fiber Matrices As Tissue Scaffold And Investigation Of Their ... -
Spermatogenezin Tasarlanmış Farklı Üç Boyutlu Fare Epididimal Beyaz Yağ Dokusu - Testis Kokültüründe Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2022)Gonadotoxic treatments in childhood cancer patients damage the testicular germ cells and microenvironment, causing 46% of the patients to become infertile. Air-liquid interphase (ALI) and U-plate (UP) techniques are ... -
Konkanavalin A Baskılanmış Yüzey Plazmon Rezonans Temelli Biyosensörün Hazırlanması
(Fen Bilimleri Enstitüsü, 2022)Within the scope of this thesis, a Concanavalin A imprinted surface plasmon resonance (SPR) biosensor was prepared for the determination of Concanavalin A. At the beginning, the surface of the SPR biosensor chip was modified ... -
Gıda Örneklerindeki Benzil Penisilin Hassas Tayinine Yönelik Moleküler Baskılanmış Polimer Temelli Optik Sensörlerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)Penicillin is one of the most commonly used beta antibiotics and has long been widely used in the treatment of various bacterial infections in humans, livestock, poultry and aquaculture. Therefore, the detection of these ... -
Pamuklu Kumaş Üzerinde Yıkanmış Kan Lekesinin Raman Spektroskopi ve Kemometri ile Tespiti
(Fen Bilimleri Enstitüsü, 2022)Bloodstains are abundant biological fluids that are encountered in crime scenes. Precise bloodstain detection on the “proof” has vitally importance for ongoing or post-commital stages. The criminal inclined to dispose the ... -
Poli(3-hidroksi bütirat)/Poli(bütilen adipat-ko-tereftalat)/İpek- Bazlı Tendon Doku İskeleleri: Karakterizasyon ve Tenojenik Aktivite
(Fen Bilimleri Enstitüsü, 2022-02)Tendon ruptures are frequently seen in tendons due to inflammation and lesions caused by factors such as mechanical stress accumulation, aging, genetic predisposition, and trauma. Tendon tissue engineering approaches are ... -
Tetrasiklin Tayinine Yönelik Aptamer Bağlı Peroksidaz Benzeri Mikropartiküllerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)Sensitive and selective methods are needed for the determination of antibiotic residues accumulated in food and water sources to protect human safety and health. Traditional methods used for determination of tetracycline ... -
İlaç Araştırmaları İçin 3-Boyutlu Mikroakışkan Damar Modelinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)There is a need for a 3-dimensional (3D) vessel model that can be used to simulate in vivo vessel physiology, anatomy, and blood flow-induced fluid tension force that can be used in the investigation of vascular diseases, ... -
Hücresizleştirilmiş Sığır Gözü Kası ve Pclkas Matriksi Kompozit Doku İskeleleriyle Göz Kası Rejenerasyonu
(Fen Bilimleri Enstitüsü, 2021)This study has been financially supported by TÜBİTAK under the project named "Extraocular Muscle Regeneration by Decellurized Bovine Extraocular Muscle and PCL-Extraocular Muscle Matrix Composite Tissue Skeleton" (1002 ... -
Akciğer Havayolu Modellemesine Yönelik Oluşturulan Deselülerize Doku İskeleleri ile 3b Hücre Kültür Sistemlerinin Kurulması
(Fen Bilimleri Enstitüsü, 2021)The lungs have the task of providing the necessary oxygen for the cells and carrying out the carbon dioxide formed as a result of metabolic events. During this process, which we call breathing, the lungs encounter many ... -
MOLEKÜLER BASKILANMIŞ KRİYOJEL DİSKLERDEN KURKUMİNİN KONTROLLÜ SALIMI
(Fen Bilimleri Enstitüsü, 2021-07)In the drug research area, the way these drugs are administered to patients is as important as developing new molecules for the treatment of diseases. In recent years, controlled drug release systems have been developed ... -
Biyobozunur Plastik Polihidroksialkanoatların Bacillus Megaterium’da Genetik Mühendisliği Yoluyla Üretiminin Artırılması
(Fen Bilimleri Enstitüsü, 2021)Fossil fuel-derived plastic materials, have currently production and consumption values at increasing quantities, due to their lightness, easy malleability and economical reasons. Owing to their poor degradation rates and ... -
Konjenital Septal Defektlerin Onarımına Yönelik Perikard Bazlı Rejeneratif Kardiyak Yamaların Doku Mühendisliği Yöntemi ile Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021-06)Cardiac patch has been used in the treatment of congenital heart disease and myocardial infarction (MI) while an ideal cardiac patch has not been developed yet. This study aimed to engineer regenerative cardiac patches by ... -
Tükürükte Eroin ve Metabolitlerinin Toksikolojik Analizinde Yeni Bir Analitik Gereç Olarak Yüzey Zenginleştirilmiş Raman Spektroskopi
(Fen Bilimleri Enstitüsü, 2021-02-19)Heroin can be detected and quantified by certain analytical methods; however, forensic professionals and criminal laboratories study for cheaper and faster detection tools. Surface-enhanced Raman spectroscopy rise as a ... -
Antibakteriyel Aljinat Mikrobaloncuk Yapıların Mikroakışkan Sistemle Hazırlanması
(Fen Bilimleri Enstitüsü, 2021)Microbubbles produced with microfluidic systems have been used as contrast agents in ultrasound radiography for approximately 30 years. In recent years, it has been successfully used in different biomedical applications ... -
İçeceklerde Bulunan Amaranth Tayinine Yönelik Sensörlerin Hazırlanması
(Fen Bilimleri Enstitüsü, 2021-06)Within the scope of the study, an Amaranth imprinted surface plasmon resonance (SPR) sensor was prepared for the determination of Amaranth, an azo group food dye used in beverages and various food products and reported to ... -
Gıda Ürünlerinde Mikrobiyal Bozulmaya Neden Olan Pseudeomonas Spp. Bakterisinin Yüzey Plazmon Rezonans (SPR) Temelli Biyosensör Kullanılarak Belirlenmesi
(Fen Bilimleri Enstitüsü, 2021)Nutrition is the intake of the nutrients they need in sufficient and balanced amounts in order to maintain healthy and quality living conditions. In order to meet the nutritional needs of the world population, which is ... -
Hücre Ölüm Yolaklarının Tespiti İçin Kağıt Tabanlı Biyosensör Tasarımı
(Fen Bilimleri Enstitüsü, 2021)The aim of the presented thesis, a paper-based biosensor design has been designed to be used in the detection of early (extrinsic pathway) and late (instrinsic pathway) stages of apoptosis. In the study, in order to ... -
Development of Jak1 Sirna Medıated Nanotherapeutıcs for Non-Melanoma Skın Cancer Therapy
(Fen Bilimleri Enstitüsü, 2021-06)Non-melanoma skin cancer is one of the most common cancers with still no effective treatment. Due to the side effects observed after long and high dose treatments and acquired resistance to the chemotherapy drugs, different ...
