Biyomühendislik
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Kontrollü Florid Salımı İçin Moleküler Baskılanmış Süpermakrogözenekli Kriyojellerin Hazırlanması
(Fen Bilimleri Enstitüsü, 2023-11-08)In this thesis, fluoride release from fluoride imprinted cryogel discs was carried out and different parameters were investigated in vitro. Cryogels are macroporous polymeric structures formed by cryojelation of ... -
Triyas-Jura Yaşlı Tabas Kömürlerinin Kimyasal Ve Petrografik Özellikleri, Orta İran
(Fen Bilimleri Enstitüsü, 2023)This thesis study aims to investigate the geochemical and petrographical properties of coals from the Parvadeh and Mazino coalfields in the Tabas Basin. This basin is in the Tabas Block of the Central Iran Region located ... -
Hasarlı Omurilik Onarımı İçin Hücre Destekli Enjekte Edilebilir İpek Fibroin Mikrotaşıyıcıların Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023-09)According to the data of the World Health Organization (WHO), spinal cord injuries affect between 250,000 and 500,000 people every year. In current clinical practice, there is no treatment method that can completely ... -
Vezikovajinal Fistül Onarımı İçin Pro-Anjiogenik/Antibakteriyel Doku İnterpozisyon Flep Eşleniğinin Tasarımı ve Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023-07)A vesicovaginal fistula (VVF) is an anbormal opening between the bladder and vagina that causes continous leakage of urine and urinary incontinence. Definitive treatment of VVF is surgery and the type of surgical intervention ... -
Sinir Doku İskelesi Olarak Modifiye Edilmiş Pedot:Pss ve Pedot:Heparin Kaplanmış Kanallar İçeren Pdms Temelli Esnek ve İletken Kompozit Filmlerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023)Within the scope of this master's thesis, conductive and flexible films based on Poly (3,4-ethylene dioxide thiophene):Poly(styrene sulfonate) (PEDOT:PSS) and Poly (3,4-ethylene dioxidethiophene):Heparin (PEHE) were studied. ... -
Akne Tedavisi için İlaç Yüklü Mikroiğneli Yamaların Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023)Acne vulgaris is a common and chronic disease, especially during adolescence, due to various factors such as inflammation of the pilosebaceous units of the skin, colonization of the Propionibacterium acnes bacterium, ... -
Yara İyileşmesine Yönelik Ekzozom Entegre Biyoaktif Jelatin Süngerlerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023)Exosomes are intercellular signal transduction vesicles, that play a role in many biological processes such as angiogenesis, antigen transport, apoptosis, coagulation, cellular hemostasis, inflammation, and intercellular ... -
Kan Pıhtılaşma Faktörlerinden Faktör VIII'in Anjiyogeneze Pozitif Etkisinin Koriyoallantoyik Membran Modelinde Gösterilmesi
(Fen Bilimleri Enstitüsü, 2023)Tissue engineering has become an approach that is frequently used in the field of health along with many disciplines today. In vascular tissue engineering, which is one of these areas, substances that affect the vascular ... -
Pankreas Kanseri Kombine Fototermal/Kemo Terapisinde Altın Nanopartiküllerle Dekore Edilmiş Sıcaklığa Duyarlı Lipozomların Kullanım Potansiyelinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2023)Pancreatic cancer is a highly fatal disease with a 5-year survival rate of 4-8% and a mortality rate of 98%. The incidence and mortality rates of this disease are increasing and it is predicted to be the second leading ... -
Epilepsi Tedavisinde Kullanılmak Üzere Fenitoin Yüklü Katı Lipid Nanopartiküllerin Sentezi ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2022)Epilepsy is a chronic neurological disease that affects 1% of the world's population and is characterized by spontaneous recurrent seizures. Common causes include pathogenic genetic variants in critical neuronal genes, ... -
Kurkumin Yüklü Üç Boyutlu Poli(ε-kaprolakton)/Kitosan Nanofibröz Yara Örtü Malzemelerinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023-01)This study was financially supported by Hacettepe University Scientific Research Projects Coordination Unit with a career initiation project titled “Development of Curcumin Loaded Macroporous Antibacterial Three-Dimensional ... -
İmplant Kaynaklı Enfeksiyon Etkeni Olan Staphylococcus Epidermidis’e Özgü Aptamer Geliştirilmesi ve Aptamerin Biyofilm Oluşumuna Etkisinin İn Vitro Koşullarda İncelenmesi
(Fen Bilimleri Enstitüsü, 2023)One of the biggest problems encountered in the clinic regarding biomaterials that replace tissues or organs damaged or lost because of accidents along with various diseases is the occurrence of infection. Staphylococcus ... -
Geliştirilen Üç Boyutlu Böbrek Proksimal Tübül Modelinde Nefrotoksisite Değerlendirmesi
(Fen Bilimleri Enstitüsü, 2023)Acute kidney injury (AKI) is an important health problem causes the death of 2 million people worldwide every year with high morbidity and mortality. One of the important causes of AKI is drug-induced nephrotoxicity. After ... -
Nano/Mikro Yapılı Çok Bileşenli Ve Sıralı İlaç Salım Sistemlerinin Diyabetik Yaralardakı Etkisinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2023)Chronic wounds of patients with metabolic problems/diabetes, which are questioned by many researchers in the field of health and which have not yet been completely cured, are one of the challenging clinical problems. ... -
Investigating the Effectiveness of Wheat Starch and Polymeric Additives on the Production of Biomedical Thermoplastic Starch Composites
(Fen Bilimleri Enstitüsü, 2023)The presence of natural polymers as biomaterials has had a desirable efficacy on the development and progress of medical science research. Starch is a natural polymer that is abundant in nature, cost-effective, biodegradable, ... -
Göz İçi Tümör Radyocerrahisi İçin Göz Takip Sistemi ve Kalite Güvence Fantomunun Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023)Uveal malignant melanoma is the most common type of intraocular cancer in adults. Stereotactic radiosurgery applications are often used in the treatment of such tumors. In these radiation treatments performed with external ... -
Kaplanmış Gözenekli Ti6Al4V İmplantların Lazer Metal Toz Ergitme (LAM) Teknolojisi ile Üretimi ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2023)Metal orthopedic implants are the pioneer medical devices for functionally providing internal repair at bone damage. The suitable mechanical properties for the applied area and biocompatibility features to prevent negative ... -
Sinir Kondüiti Olarak Metakrilatlanmış Jelatin Modifiye Hücresizleştirilmiş Koyun İnce Bağırsak Submukozasının Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023)Peripheral nerve damage is a common injury because of trauma. The slow regeneration of the complicated structure of the peripheral nervous system highly affects the regainment of function. Hence nerve tissue engineering ... -
Anti-Her2 SCFV Antikor Fragmanının Escherichia coli Bakterisinde Üretim Bölgesinin Optimizasyonu
(Fen Bilimleri Enstitüsü, 2022)Antibodies and antibody fragments are used in the diagnosis, imaging, and target-specific treatments of various diseases such as cancer and viral infections. It also has an important place in combating infectious diseases. ... -
Kontrollü Bor Salan Biyobozunur Yara Örtülerinin Geliştirilmesi ve Dermal/Mukozal Rejenerasyonda Kullanımlarının Araştırılması
(Fen Bilimleri Enstitüsü, 2022)The following thesis presents the development of fiber matrices containing boron (B), which has therapeutic effects in wound healing, and montmorillonite (MMT) as nanoclay. These are specifically used in the treatment of ...
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