Biyomühendislik: Güncel gönderi
Toplam kayıt 76, listelenen: 21-40
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Pankreas Kanseri Kombine Fototermal/Kemo Terapisinde Altın Nanopartiküllerle Dekore Edilmiş Sıcaklığa Duyarlı Lipozomların Kullanım Potansiyelinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2023)Pancreatic cancer is a highly fatal disease with a 5-year survival rate of 4-8% and a mortality rate of 98%. The incidence and mortality rates of this disease are increasing and it is predicted to be the second leading ... -
Epilepsi Tedavisinde Kullanılmak Üzere Fenitoin Yüklü Katı Lipid Nanopartiküllerin Sentezi ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2022)Epilepsy is a chronic neurological disease that affects 1% of the world's population and is characterized by spontaneous recurrent seizures. Common causes include pathogenic genetic variants in critical neuronal genes, ... -
Kurkumin Yüklü Üç Boyutlu Poli(ε-kaprolakton)/Kitosan Nanofibröz Yara Örtü Malzemelerinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023-01)This study was financially supported by Hacettepe University Scientific Research Projects Coordination Unit with a career initiation project titled “Development of Curcumin Loaded Macroporous Antibacterial Three-Dimensional ... -
İmplant Kaynaklı Enfeksiyon Etkeni Olan Staphylococcus Epidermidis’e Özgü Aptamer Geliştirilmesi ve Aptamerin Biyofilm Oluşumuna Etkisinin İn Vitro Koşullarda İncelenmesi
(Fen Bilimleri Enstitüsü, 2023)One of the biggest problems encountered in the clinic regarding biomaterials that replace tissues or organs damaged or lost because of accidents along with various diseases is the occurrence of infection. Staphylococcus ... -
Geliştirilen Üç Boyutlu Böbrek Proksimal Tübül Modelinde Nefrotoksisite Değerlendirmesi
(Fen Bilimleri Enstitüsü, 2023)Acute kidney injury (AKI) is an important health problem causes the death of 2 million people worldwide every year with high morbidity and mortality. One of the important causes of AKI is drug-induced nephrotoxicity. After ... -
Nano/Mikro Yapılı Çok Bileşenli Ve Sıralı İlaç Salım Sistemlerinin Diyabetik Yaralardakı Etkisinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2023)Chronic wounds of patients with metabolic problems/diabetes, which are questioned by many researchers in the field of health and which have not yet been completely cured, are one of the challenging clinical problems. ... -
Investigating the Effectiveness of Wheat Starch and Polymeric Additives on the Production of Biomedical Thermoplastic Starch Composites
(Fen Bilimleri Enstitüsü, 2023)The presence of natural polymers as biomaterials has had a desirable efficacy on the development and progress of medical science research. Starch is a natural polymer that is abundant in nature, cost-effective, biodegradable, ... -
Göz İçi Tümör Radyocerrahisi İçin Göz Takip Sistemi ve Kalite Güvence Fantomunun Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023)Uveal malignant melanoma is the most common type of intraocular cancer in adults. Stereotactic radiosurgery applications are often used in the treatment of such tumors. In these radiation treatments performed with external ... -
Kaplanmış Gözenekli Ti6Al4V İmplantların Lazer Metal Toz Ergitme (LAM) Teknolojisi ile Üretimi ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2023)Metal orthopedic implants are the pioneer medical devices for functionally providing internal repair at bone damage. The suitable mechanical properties for the applied area and biocompatibility features to prevent negative ... -
Sinir Kondüiti Olarak Metakrilatlanmış Jelatin Modifiye Hücresizleştirilmiş Koyun İnce Bağırsak Submukozasının Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023)Peripheral nerve damage is a common injury because of trauma. The slow regeneration of the complicated structure of the peripheral nervous system highly affects the regainment of function. Hence nerve tissue engineering ... -
Anti-Her2 SCFV Antikor Fragmanının Escherichia coli Bakterisinde Üretim Bölgesinin Optimizasyonu
(Fen Bilimleri Enstitüsü, 2022)Antibodies and antibody fragments are used in the diagnosis, imaging, and target-specific treatments of various diseases such as cancer and viral infections. It also has an important place in combating infectious diseases. ... -
Kontrollü Bor Salan Biyobozunur Yara Örtülerinin Geliştirilmesi ve Dermal/Mukozal Rejenerasyonda Kullanımlarının Araştırılması
(Fen Bilimleri Enstitüsü, 2022)The following thesis presents the development of fiber matrices containing boron (B), which has therapeutic effects in wound healing, and montmorillonite (MMT) as nanoclay. These are specifically used in the treatment of ... -
Havayolu Modellemesi Amaçlı Tasarlanan Mühendislik Ürünü 3B Hücre Kültür Sistemlerinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2022-06)Chronic airway diseases have a complex set of mechanisms in which environmental and genetic factors play a role. It is very important to study the molecular pathologies of these diseases and to establish suitable cellular ... -
Kemik Tümörlerinde Lipozomal Kannabinoidlerin Reseptör Aracılı Antiproliferatif ve Apoptotik Etkilerinin Araştırılması
(Fen Bilimleri Enstitüsü, 2022-12-30)Primary osteosarcoma is the most common osteogenic tumor in children and adolescents, known with its rapid metastasis. The limitations of the treatment approaches applied in the clinic and the side effects observed in ... -
Böbrek Transplantasyonu Yapılacak PRA (Panel Reaktif Antikor) Pozitif Hastalarda Hla Haplotipleri İle İmmünofenotip İlişkisinin Araştırılması
(Fen Bilimleri Enstitüsü, 2022)The Human Leukocyte Antigen (HLA- Human Leucocyte Antigen) has an extremely complex morphology. This complex structure is an important factor that causes incompatibility between the patient and the donor, especially when ... -
Yüzey Plazmon Rezonans Sensörü ile Sentetik Reseptörler Kullanılarak Sütte Bulunan Benzilpenisilinin Tayini
(Fen Bilimleri Enstitüsü, 2022)Antibiotic residues in food products, drinking water and the environment cause the emergence of antibiotic-resistant bacterial strains, disruption of the normal ecological balance, and serious health consequences, including ... -
Kurkumin Tayinine Yönelik Yüzey Plazmon Rezonans Temelli Nanosensörlerin Hazırlanması
(Fen Bilimleri Enstitüsü, 2021-12)Herbal ingredients are among the most used products in alternative and complementary medicine. Curcumin, which is obtained from Curcuma longa plant known as Indian saffron or turmeric, has become quite popular in recent ... -
Centella Asıatıca Bitki Özütü ile Kaplı Gümüş Nanopartikül İçeren Polimer Liflerin Yara İyileştirici Etkisinin in Vitro ve in Vivo Araştırılması
(Fen Bilimleri Enstitüsü, 2021)In this study, we synthesized functional silver nanoparticles (AgNPs) from silver ions using the therapeutic plant extract of Centella asiatica (CA). The formation of AgNPs coated with CA functional groups (CA-AgNPs) is ... -
Deselülerize Miyokard-Elastomer Yamaların Hazırlanması ve In Vitro Performanslarının İncelenmesi
(Fen Bilimleri Enstitüsü, 2021)Heart failure is the final stage of most cardiovascular diseases, such as myocardial infarction. Unlike other tissues such as bone and skin, heart tissue does not have the ability to regenerate and repair itself. This ... -
Adenozin Tayinine Yönelik Optik Temelli Nanosensörlerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2022-01)In this thesis, a novel measurement method is proposed to measure the level of adenosine nucleoside which is a significant molecule utilized as a direct or indirect indicator to detect diseases such as neurodegenerative ...
