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3 Boyutlu Baskı Teknolojisi Kullanılarak Hastaya Özgün Konturlarla Oluşturulan Fantom Tasarımı ve Üretimi ile Mikro-Çok Yapraklı Kolimatör Tabanlı Beyin ve Başboyun Yoğunluk Ayarlı Radyoterapi Planlarının Kalite Kontrolü

SUNEL, Sercan (Sağlık Bilimleri Enstitüsü, 2017)

SUNEL, S. Quality control of micro-multileaf collimator based brain and head-and-neck intensity modulated radiotherapy plans with patient-specific phantom design and production using 3D printing technology. Hacettepe ...

3′End Maturation of Human Telomerase Rna Component (Terc) and Its Effects on Telomere Dynamics

BOYRAZ, BARIŞ (Sağlık Bilimleri Enstitüsü, 2017-09-15)

Telomerase RNA Component (TERC) is the non-coding RNA template and scaffold of the telomerase holoenzyme. TERC level has been shown to be a limiting factor for telomerase activity, lower levels resulting in telomere diseases ...

Adjuvan Radyoterapi Planlanan Jinekolojik Kanserli Olgularda Radyoterapi Sırasındaki Kilo Değişiklikleri ve Organ Hareketlerine Bağlı Dozimetrik Değişikliklerin İncelenmesi

Yılmaz, Ceyran (Kanser Enstitüsü, 2014)

In this study, planned curative surgery and postoperative adjuvant radiotherapy (RT), 10 patient with gynecological tumors taken for planning purposes at the beginning of treatment with computed tomography (CT) taken in ...

Akciğer Kanser Hücrelerinden Salınan Eksozomların Makrofaj Polarizasyonuna ve Fonksiyonlarına Etkisinin Araştırılması

Dalkıran, Başak (Kanser Enstitüsü, 2021)

Lung cancer has the highest mortality rate in both men and women worldwide. With our developing technology and knowledge, the research of methods in cancer targeted treatments have turned to target such as tumor microenvironment, ...

Akciğer Kanseri ve Sol Meme Radyoterapisinde Kardiyak Altyapı Marjlarının Oluşturulması ve Tedavi Planı Optimizasyonu

Dalgıç, Eylem (Kanser Enstitüsü, 2023)

In thoracic irradiations, the coronary arteries (CA) are involuntarily exposed to radiation and subsequent cardiovascular toxicities may occur. To avoid this, the importance of accurately creating the safety margins (SM) ...

Akciğer Kanserlerinde Stereotaktik Ablatif Beden Radyoterapisinin Toksisite ve Doz - Yanıt İlişkisinin Matematiksel Model ile Görüntü ve Dozimetrik Analizi

Akbayırlı, Uğur (Kanser Enstitüsü, 2017-02-17)

In conventional radiotherapy applications, clinicians and physicist rely upon mathematical dose - response models for applied doses to tumor and periphery healthy tissues. However in stereotactic ablative body radiotherapy ...

All-Trans Retinoik Asit (Atra) ve 1Α,25-Dihidroksivitamin D3 (Vitamin D3) ile Uyarılan Akut Miyeloid Lösemi Hücrelerinin T Hücre Yanıtları Üzerine Etkisi

Yöyen Ermiş, Diğdem (Kanser Enstitüsü, 2014)

ATRA and D3 are the active metabolites of vitamin A and D, respectively. In this study, HL-60 myeloid leukemia cells were progressed through different maturation stages with ATRA, D3, LPS, and IFN-γ. For the determination ...

Aml Hastalarında Nkp30 Ve B7-H6, Gal-3, Bag6 Ekspresyon Düzeyleri İle Nk Hücre Sitotoksitesi Arasındaki İlişki

Aydın, Büşra (Kanser Enstitüsü, 2020-01-10)

ABSTRACT Aydın,B. The relationship between NKp30 and B7-H6, Gal-3, BAG6 expression levels and NK cell cytotoxicity in AML patients. Master of Science Thesis of Hacettepe University Graduate School of Health Sciences ...

Bortezomib ve İmatinib'in Pankreas Kanserinde Olası Sinerjistik Etkisinin İncelenmesi

Pişiren, Gaye (Sağlık Bilimleri Enstitüsü, 2023-05-22)

The high mortality rate among pancreatic cancer patients underlines the importance of proper treatment. However, the traditional treatment strategies remain inadequate indicating that alternative therapy options need to ...

Cancer Associated Fibroblasts Have Phenotypic and Functional Characteristics Similar To The Fibrocytes That Represent A Novel Mdsc Subset

Günaydın, Gürcan; Kesikli, S. Altug; Güç, Dicle (Taylor & Francis Inc, 2015)

Circulating fibrocytes were reported to represent a novel myeloid-derived suppressor cell (MDSC) subset and they were also proposed to be involved in the tumor immune escape. This novel fibrocyte subset had a surface ...

Cancer Burden In Four Countries Of The Middle East Cancer Consortium (Cyprus; Jordan; Israel; Izmir (Turkey)) With Comparison To The United States Surveillance; Epidemiology And End Results Program

Anton-Culver, Hoda; Chang, Jenny; Bray, Freddie; Znaor, Ariana; Stevens, Lisa; Eser, Sultan; Silverman, Barbara; Nimri, Omar; Pavlou, Pavlos; Charalambous, Haris; Demetriou, Anna; Ward, Kevin; Ziogas, Argyrios (Elsevier Sci Ltd, 2016)

It is important that population-based cancer registries provide accurate and reliable data for public health purposes. These data are essential data for planning of cancer control and prevention. In this study, we examined ...

Cancer Trends and Incidence and Mortality Patterns in Turkey

Tunca, Dilara; Tuncer, Murat; Yılmaz, Hakkı Hakan; Yazıhan, Nuray; Sevinç, Arzu; Olcayto, Emire Özen; Özgül, Nejat (Oxford Univ Press, 2011)

Cancer incidence and mortality rates have been increasing in Turkey as most of the developing countries. Besides socioeconomic factors, one of the most prominent attributes of developing countries is the dissimilarity of ...

Comparatıve Analysıs of Myeloıd-Derıved Suppressor Cells From Blood and Spleen in Gastrıc and Pancreatıc Cancer

Tavukçuoğlu, Ece (Sağlık Bilimleri Enstitüsü, 2022-07-29)

Under physiological conditions, development and maturation of the myeloid cells take place in the bone marrow. In case of chronic inflammatory disorders such as cancer, production of chemokines, growth factors, and cytokines ...

Cxcl Kemokı̇n ÖncüL Dı̇zelerı̇nden Türevlenen Küçük Peptı̇t MoleküLlerı̇nin İmmün Düzenleyı̇cı̇ Etkı̇sinin Değerlendirmesı̇

Yöyen Ermiş, Diğdem (Kanser Enstitüsü, 2019-03-12)

Peptide structured small molecules function in the regulation of a variety of physiological processes and intercellular communication. In this study, precursor sequences of known 17 CXCL chemokine molecules were analyzed ...

Cyberknife Synchrony® Solunum Takip Sisteminin Polimer Jel Dozimetre ile Üç Boyutlu Performans Analizi

Şahin, Meryem Cansu (Kanser Enstitüsü, 2017-02-20)

ŞAHİN, M. C. Three Dimensional Performance Analysis Of Cyberknife Synchrony® Respiratory Tracking System Using Polymer Gel Dosimeter. Hacettepe University Institute of Health Sciences, Thesis in Radiotherapy Physics ...

CyberKnife® Robotik Radyocerrahi Cihazında MAGIC Polimer Jel Dozimetre İle Küçük Alan Dozimetrisinin İncelenmesi

ENKAVİ, Mehmet Fazıl (Kanser Enstitüsü, 2018)

ENKAVİ, M.F. Investigation of Small Field Dosimetry with MAGIC Polymer Gel Dosimeter in CyberKnife® Robotic Radiosurgery Device. Hacettepe University Institute of Health Sciences, MSc. Thesis in Radiotherapy Physics Program, ...

Cyberknife® ve Varian RapidArc® TrilogyTM Cihazında Üç Boyutlu Uzaysal Fraksiyone Grid Terapi Doz Karakteristiklerinin Karşılaştırılması

Ertan, Ferihan (Kanser Enstitüsü, 2020-12)

. Lattice therapy is an innovative method to increase the effectiveness of radiotherapy by delivering a high dose to the target volume irradiated through small spaces in one or more fractions.In this study, we investigated ...