Hacettepe Üniversitesi Açık Erişim Sistemi (HÜAES)
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FARKLI TARIM YÖNTEMLERİ VE HASAT ZAMANININ DOMATESLERİN ANTİOKSİDAN BİLEŞİKLERİ VE ANTİOKSİDAN AKTİVİTESİ ÜZERİNE ETKİSİ
(2026) AYLİN İŞLER; Beslenme Bilimleri
Tomato (Solanum lycopersicum) is an important fruit in human nutrition due to its rich content of bioactive compounds with antioxidant properties, including lycopene, β-carotene, ascorbic acid, and phenolic compounds. The antioxidant activity of tomatoes may be influenced by several factors such as genotype, environmental conditions, harvest time, and cultivation practices. This study aimed to compare the antioxidant activities of tomatoes cultivated under organic (Afyon-Başmakçı), conventional (Denizli-Sarayköy), and soilless (Afyon-Sandıklı) agricultural production systems, with samples collected in June and August. The samples were freeze-dried and extracted with 80% ethanol, and their antioxidant activities were evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. Antioxidant activity was determined by calculating the half-maximal inhibitory concentration (IC₅₀) values of the extracts. The IC₅₀ values of the tomato samples ranged between 97.93 and 947.10 µg/mL. Among the samples
harvested in June, the highest antioxidant activity was observed in the soilless-grown tomato (H.T.: 423.54 µg/mL), followed by conventional (H.K.: 486.15 µg/mL) and organic (H.O.: 670.18 µg/mL) samples. Among the samples harvested in August, the
highest antioxidant activity was observed in the conventional sample (A.K.: 97.93 µg/mL), followed by organic (A.O.: 898.15 µg/mL) and soilless-grown (A.T.: 947.10 µg/mL) samples. When compared across harvest periods, antioxidant activity increased in the conventional sample from June to August, whereas it decreased markedly in both organic and soilless-grown samples. These findings demonstrated that antioxidant activity varied considerably not only by cultivation method but also by harvest time. In conclusion, the antioxidant activity of tomatoes appears to be influenced not only by cultivation method but also by factors such as harvest time, environmental conditions, and genotype. Therefore, the evaluation of different agricultural production systems should consider all factors affecting nutritional quality rather than cultivation method alone.
OTİZMLİ ÇOCUKLARIN EBEVEYNLERİNDE PSİKOLOJİK DAYANIKLILIK, OKUPASYONEL KATILIM, YETERLİLİK VE DENGENİN İNCELENMESİ
(Sağlık Bilimleri Enstitüsü, 2026-06-30) Gamze Ayşe Kellecioğlu; Ergoterapi
Kellecioğlu, A.G., Investigation of Psychological Resilience, Occupational
Participation, Competence, and Balance in Parents of Children with Autism,
Hacettepe University Health Sciences Graduate School Occupational Therapy
Program Master's Thesis, Ankara, 2026. This research aimed to examine the
occupational balance, participation, and psychological resilience in parents of children
with autism. The study included 56 parent dyads (total n=112) of children with Autism
Spectrum Disorder (ASD). Data were collected via face-to-face interviews using the
Occupational Balance Questionnaire (OBQ11-T), Model of Human Occupation
Screening Tool (MOHOST), Occupational Self-Assessment (OSA), and Resilience
Scale for Adults (RSA). Results showed no significant differences in total scores of
occupational balance, competence, and resilience between genders (p>0.05).
However, in MOHOST subscales, mothers scored significantly higher in Volition
(p=0.047), Habituation (p=0.002), and Environment (p=0.035) than fathers. Total
MOHOST scores were significantly higher in favor of mothers (Med: 63.5) than
fathers (Med: 60.0) (p=0.004). OSA data revealed that while responsibility
competence was high in both groups, mothers scored significantly lower in personal
occupations like self-care and leisure (p<0.05). A positive, moderate correlation was
found between fathers' resilience and mothers' occupational participation (rho=0.305;
p=0.022). Significant positive correlations also existed between mothers' occupational
balance and their resilience (rho=0.287) and competence perceptions (rho=0.402). In
conclusion, although mothers have higher occupational participation levels, they
experience significant restrictions in personal occupations; as fathers' psychological
resilience increases, mothers' occupational participation also increases, and fathers'
psychological resilience shows a significant positive correlation with mothers'
participation process. Based on these findings, developing family-based occupational
therapy strategies aimed at increasing fathers' resilience to balance the maternal
occupational burden are recommended.
Gastrointestinal Sistem Kanseri Tanısı Konmuş Hastaların Beslenme Durumu ve Yaşam Kalitesinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2026) Şimşek, Gamze; Beslenme ve Diyetetik
Şimşek G., Assessment of Nutritional Status and Quality of Life in Patients with Gastrointestinal Cancer, Hacettepe University Graduate School of Health Sciences, Dietetics Program Master’s Thesis, Ankara, 2026. This study, conducted to evaluate the relationship between adherence to the Mediterranean diet and the nutritional status and quality of life of patients with Gastrointestinal (GI) cancer, was carried out between September 2025 and April 2026 at University Hospital. A total of 117 individuals diagnosed with GI cancer (61 men and 56 women), with a median age of 63.0 years, were included in the study. A face-toface questionnaire was administered to determine the demographic and anthropometric characteristics and the medical histories of the participants. Participants' dietary intake was assessed using a food frequency questionnaire, their adherence to the Mediterranean diet using the Mediterranean Diet Adherence Screener (MEDAS), their malnutrition status using the Nutritional Risk Screening (NRS-2002), and their quality of life using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30). A decrease was found in participants' body weight and Body mass index (BMI) values between the pre-diagnosis period and the time of the interview (p<0.001). 48.7% of the participants (n=57) were found to adhere to the Mediterranean diet, while 51.8% (n=60) were found not to adhere to it. Among individuals adhering to the Mediterranean diet, consumption of vegetables, fruits, eggs, and dried legumes/oilseeds was found to be higher than among those who did not adhere to the diet (p<0.05). Among individuals adhering to the Mediterranean diet, social functioning scores were found to be higher (p<0.05) and economic hardship scores were found to be lower (p<0.05) compared to those who did not adhere to the diet. Compared with individuals not at risk, those at risk of malnutrition had lower Global Health Status/QoL (p<0.05), Physical Functioning (p<0.001), Role Functioning (p<0.05), and Social Functioning (p<0.001) scores, and higher Fatigue (p<0.001), Nausea/Vomiting (p<0.05), Pain (p<0.05), Appetite Loss (p<0.001), and Financial Difficulties (p<0.05) scores. The percentage of weight loss was negatively correlated with Global Health Status/QoL, Physical Functioning, and Role Functioning, and positively correlated with Fatigue, Appetite Loss, Financial Difficulties, Pain, Dyspnoea, and Nausea/Vomiting (p<0.05). Daily protein (g) and energy (kcal) intake was positively associated with Global Health Status/QoL and negatively associated with Fatigue and Appetite Loss scores; and daily fiber (g) intake was negatively associated with Fatigue and Appetite Loss scores (p<0.05). Age (p=0.002) and current BMI (p<0.05) were identified as independent risk factors for malnutrition risk. MEDAS adherence showed a borderline significant protective effect against malnutrition risk (p=0.05). The risk of malnutrition (p<0.05) and protein intake (g/kg) (p<0.05) were identified as independent determinants of low quality of life. Early nutritional assessment and intervention in patients with GI cancer are critical for improving their quality of life. Keywords
BAKIMEVİNDE YAŞAYAN ALZHEİMER TANILI GERİATRİK BİREYLERDE HEDEF ODAKLI ÇİZGİ DANSININ ETKİLERİ: RANDOMİZE KONTROLLÜ ÇALIŞMA
(Sağlık Bilimleri Enstitüsü, 2026-07-29) YAZGI Yasemin; Ergoterapi
Alzheimer’s disease is a neurodegenerative disorder characterized by cognitive decline, balance impairments, psychological symptoms, and dependence in activities of daily living. This study aimed to investigate the effects of goal-oriented line dancing on cognitive performance, balance, anxiety, depression, activities of daily living, sleep, and quality of life in institutionalized older adults with Alzheimer’s disease. A total of 42 individuals aged 65 years and older with mild to moderate Alzheimer’s disease were included in the study. Participants were randomly assigned to an intervention group (n=20) and a control group (n=22). Participants in the intervention group received goal-oriented line dance, whereas the control group received no intervention. Assessments were performed using the Alzheimer’s Disease Assessment Scale-Cognitive Subscale (ADAS-Cog), Hospital Anxiety and Depression Scale (HADS), Berg Balance Scale, Alzheimer’s Disease Cooperative Study–Activities of Daily Living Scale (ADCS-ADL), Assessment of Sleep Complaints Using the Visual Analogue Scale, and Quality of Life in Alzheimer’s Disease Scale. Following the intervention, significant improvements were observed in cognitive performance, balance, and quality of life in the line dancing group (p<0.05). In addition, anxiety and depression levels decreased significantly (p<0.05). Although positive changes were observed in activities of daily living and sleep-related outcomes, improvements in some parameters remained limited. In conclusion, goal-oriented line dancing appears to be a feasible non-pharmacological intervention that may provide beneficial cognitive, physical, and psychosocial outcomes in older adults with Alzheimer’s disease.
ERGOTERAPİ LİSANS ÖĞRENCİLERİ VE YENİ MEZUN ERGOTERAPİSTLERİN ÜSTBİLİŞ BECERİLERİNİN VE ÜSTBİLİŞSEL FARKINDALIKLARININ İNCELENMESİ
(Sağlık Bilimleri Enstitüsü, 2026) YASEMİN KOCAPINAR; Ergoterapi
Kocapınar Y. Investigation of Metacognitive Skills and Metacognitive Awareness of Occupational Therapy Undergraduate Students and New Graduate
Occupational Therapists, Hacettepe University Graduate School of Health Sciences Occupational Therapy Program Master's Thesis, Ankara, 2026. The
purpose of this study was to examine the metacognitive awareness, critical thinking, reflective thinking, and problem-solving skills of undergraduate occupational therapy students and recent graduates, and to understand the experiential reflections of these processes. A mixed-methods design was adopted. The study included 231 participants for the quantitative phase and 17 participants for the qualitative phase. Sociodemographic Information Form, Metacognitive Awareness Inventory, California Critical Thinking Disposition Scale, Reflective Thinking Scale, Problem Solving Inventory, and a semi structured interview form were used. Participants' metacognitive awareness was high, while their critical thinking, reflective thinking, and problem
solving skills were at moderate levels. Female participants demonstrated higher reflective thinking, planning, and debugging skills than males. While childhood location showed no significant difference (p>0.05), participants with higher maternal education had better information management and problem-solving perceptions, and those with higher academic success perceptions had higher metacognitive awareness, critical, and reflective thinking levels. Qualitative analysis yielded eight themes: Awareness Recognition, Analysis-Interpretation, Questioning-Evaluation, Strategy Development-Planning, Decision Making-Implementation, Monitoring-Self Regulation, Evaluation-Reflection-Learning, and Occupational Therapy-Specific Skills. "Awareness and Recognition" emerged as the most intense theme, reinforcing quantitative findings. In conclusion, metacognitive awareness falls short of
transforming into action-oriented higher-order thinking skills, suggesting that supporting these skills in an explicit, guided, and systematic manner within occupational therapy education could have positive effects.