Hacettepe Üniversitesi Açık Erişim Sistemi (HÜAES)
- HÜAES, Hacettepe Üniversitesi bünyesinde üretilen kitap, makale, tez, bildiri, rapor gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, etkisini artırmak için telif haklarına uygun olarak Açık Erişime sunar.
- Ankara State Conservatory
- Directorates
- Faculty of Dentistry
- Faculty of Pharmacy
- Faculty of Letters
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Nörolojik Hastalıklarda İntravenöz İmmünoglobulin Tedavisinin Komplikasyonları
(Nörolojik Bilimler ve Psikiyatri Enstitüsü, 2026-09-01) Gülen Gül Mert; Klinik Nörolojik Bilimler ve Psikiyatri
This study aimed to evaluate the frequency, characteristics, and associated risk factors of adverse events, as well as long-term functional outcomes, in pediatric patients receiving intravenous immunoglobulin (IVIG) therapy for neurological indications. A retrospective analysis was conducted on 53 patients aged 1 month to 18 years who received IVIG at the Çukurova University Faculty of Medicine, Division of Pediatric Neurology, between January 1, 2018, and January 31, 2023. Demographic and clinical data, infusion characteristics, adverse events, and modified Rankin Scale (mRS) scores at admission, discharge, and the one-year follow-up were evaluated. A total of 427 IVIG courses and 1,708 infusions were administered to the patients. The mean age was 9.4 ± 5.3 years, and 58% of the patients were male. The most common indication was Guillain-Barré syndrome (74%). At least one adverse event occurred in 28% (n=15) of the patients. Most events were mild in severity; fever and headache were the most frequently observed, while thromboembolic events were detected in two patients. Among patients who experienced adverse events, 66.7% developed the event during the first course. The rate of adverse events was higher in patients receiving short-duration infusions (p<0.001). In multivariate logistic regression, infusion duration was the only significant independent predictor; the odds of developing an adverse event with a 4–6 hour infusion were approximately 78 times higher than with a 6–8 hour infusion (OR=78.20; 95% CI: 6.48–943.47; p<0.001). The rate of functional independence (mRS 0–2) was 21% at admission, 81% at discharge, and 94% at one year. Most IVIG-related adverse events were mild. The concentration of events during the first course and their association with short infusion duration support the individualization of infusion rates and close clinical monitoring, particularly during initial administrations.
Estetik Diş Hekimliği Uygulamalarında Etik: Ankara İlinde Nitel Bir Araştırma
(Sağlık Bilimleri Enstitüsü, 2027) İlkim Karakapıcı; Tıp Tarihi ve Etik
This doctoral dissertation was conducted to identify the ethical issues in aesthetic dentistry and to evaluate the relationship between aesthetic dental practices and the commercialization of healthcare. A qualitative research design was employed. Dentists who predominantly perform aesthetic dental procedures in Ankara were identified, and in-depth interviews were conducted with 20 participants. The data obtained were analyzed using thematic analysis. The findings revealed that an externally driven patient demand for aesthetic procedures has been created, that patient autonomy is influenced by this process, that dentists attempt to balance the principles of non-maleficence and respect for autonomy, and that, alongside the commercialization of healthcare, aesthetic dentistry has also become highly commercialized, with extensive use of marketing strategies.
Ege’nin İki Yakası Aydın Ve Grevena Çevresinde Mübadelenin -Zorunlu Göçün- Yarattığı Kültürel Değişmeler
(Sosyal Bilimler Enstitüsü, 2025) Gürbüz, Duru Özden; Türk Halkbilimi
This thesis aims to compare how the exchangees settled in the province of Aydin in Anatolia and the Grevena Region of Greece based on the Exchange Agreement signed between the Government of the Turkish Grand National Assembly and Greece in 1923, and the local people of both countries made sense of this process and to demonstrate the effects of the exchange on these groups. I n the field studies conducted in these regions, interviews were carried out with the second, third generations through participatory or
non-participatory observation and semi-structured conversations. These interviews were evaluated comparatively in order to comprehend and make sense of the pre- and post-exchange periods by making use of archival sources, newspapers of the period, books and articles written on the topic. Following general information given in the introduction part of the study, the first section provides information about the subject and scope of the study, its field, importance, purpose and boundaries, the process of the study, the
method used in the study and the theoretical framework. The second section explains the conceptual structure and theoretical basis related to the study such as migration, types of migration, exchange, population exchange, exchangee, integration, culture, identity, cultural identity, nation-state concept, and the cultural and identity policies of nation-states. The third section examines history and memory in the context of exchange. The historical processes before and after the Lausanne Exchange are discussed in the
context of Turkish-Greek relations. The geographies and histories of Aydın and Grevena Region, the migration process, understanding of historical memory and space of the exchangees are emphasized. In the
fourth section, it is examined how the process of exchange affected the native peoples and the exchangees who were tested by displacement, the construction of cultural identities emerged after acculturation,
whether the exchangees were able to preserve their identities, how the cultural identity was transmitted, and how the exchange that started with the concept of nation state was gradually evolved into transnational
transformations in other generations. Information is provided on the changes in their languages, human conditions and economic structures, exchangee residences, faith structures and religious identities. In the
fifth section, the material and spiritual elements, rituals, relations and cultural changes constituting the culture that the exchangees continued to have or already forgot are explained. In the conclusion part of the
study, an evaluation is made based on the analysis done on the field and on the principle of the integrity of the socio-cultural universe, taken as basis by folklore, which is a comparative discipline, and it is stated that it will be a guiding study in the processes of similar migration cases that may occur in the future.
Karaçay-Balkarcada Çokluk ve İyelik Çekimi
(Sosyal Bilimler Enstitüsü, 2025) Elibol, Sümeyye; Çağdaş Türk Lehçeleri ve Edebiyatları
This study investigates two core categories of nominal inflectional morphology in Karachay-Balkar: Plurality and possessive constructions. The theoretical framework of the research is based on morphological and functional linguistic approaches, and the data is drawn from the short story Aç Eşikni Menme by Hasan Şavayev. The plural category in Karachay-Balkar is primarily marked by the morpheme {+lA}, which phonologically diverges from the common Turkic plural suffix {+lAr}. The study analyzes the syntactic placement of the plural marker and its morphological interactions with
possessive suffixes. Possessive structures are examined with respect to person and number agreement, and classified according to their specificity, including definite, indefinite, and pronominal possessive types based on textual examples. The findings reveal that plural and possessive inflections in KarachayBalkar reflect not only formal variation but also functional patterns that are shaped by both universal Turkic paradigms and language-internal developments. The research contributes to the understanding of Karachay-Balkar morphology as a system that aligns with broader Turkic typology while developing different structural features due to language contact.
Sağlık Bilgi Altyapısında Veri Sürtünmesi: Mobil Sağlık Uygulamaları
(Sosyal Bilimler Enstitüsü, 2025) Badem Rutbil,Gökçen; Bilgi ve Belge Yönetimi
Effective and reliable management of health data is critically important for patient safety, the success of treatment processes, and the delivery of sustainable healthcare services. However, “data frictions”
encountered in health information systems and mobile health (m-health) applications create significant barriers in integration, sharing, and analysis processes. These frictions limit the full potential of the digital
health ecosystem and reduce the effectiveness of clinical decision support mechanisms. In this study, data frictions arising during the integration of data obtained from m-health applications into health information systems were comprehensively examined across technical, standard, institutional, and
legal dimensions. The research was conducted within the scope of the HSMonitor Project. Data collection involved active observation, document analysis, and interviews with healthcare professionals and technical
staff. The qualitative data obtained were analyzed using thematic analysis.
The findings reveal that m-health systems face multi-layered data frictions. These include disruptions in real-time data transmission, limitations in device accuracy and system performance, incompatibilities
between coding systems, deficiencies in system integration, inadequacies of personalized algorithms, misalignments with workflow processes, deficits in digital and health literacy, and regulatory restrictions.
In conclusion, for m-health applications to be implemented effectively, reliably, and sustainably, it is necessary to develop technologies that enable automated data transmission, ensure device standardization
and calibration, achieve full compliance with national and international coding systems, apply personalized clinical decision support algorithms, enhance digital and health literacy, and establish flexible yet secure
legal frameworks for data sharing. This study emphasizes the need for a multidimensional and holistic transformation to enable the integrated operation of m-health applications with health information
infrastructures and provides concrete recommendations for stakeholders in this regard.