Browsing Kanser Enstitüsü by Rights "info:eu-repo/semantics/openAccess"
Now showing items 1-20 of 79
-
3′End Maturation of Human Telomerase Rna Component (Terc) and Its Effects on Telomere Dynamics
(Sağlık Bilimleri Enstitüsü, 2017-09-15)Telomerase RNA Component (TERC) is the non-coding RNA template and scaffold of the telomerase holoenzyme. TERC level has been shown to be a limiting factor for telomerase activity, lower levels resulting in telomere diseases ... -
Akciğer Kanser Hücrelerinden Salınan Eksozomların Makrofaj Polarizasyonuna ve Fonksiyonlarına Etkisinin Araştırılması
(Kanser Enstitüsü, 2021)Lung cancer has the highest mortality rate in both men and women worldwide. With our developing technology and knowledge, the research of methods in cancer targeted treatments have turned to target such as tumor microenvironment, ... -
Akciğer Kanseri ve Sol Meme Radyoterapisinde Kardiyak Altyapı Marjlarının Oluşturulması ve Tedavi Planı Optimizasyonu
(Kanser Enstitüsü, 2023)In thoracic irradiations, the coronary arteries (CA) are involuntarily exposed to radiation and subsequent cardiovascular toxicities may occur. To avoid this, the importance of accurately creating the safety margins (SM) ... -
Aml Hastalarında Nkp30 Ve B7-H6, Gal-3, Bag6 Ekspresyon Düzeyleri İle Nk Hücre Sitotoksitesi Arasındaki İlişki
(Kanser Enstitüsü, 2020-01-10)ABSTRACT Aydın,B. The relationship between NKp30 and B7-H6, Gal-3, BAG6 expression levels and NK cell cytotoxicity in AML patients. Master of Science Thesis of Hacettepe University Graduate School of Health Sciences ... -
Bortezomib ve İmatinib'in Pankreas Kanserinde Olası Sinerjistik Etkisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023-05-22)The high mortality rate among pancreatic cancer patients underlines the importance of proper treatment. However, the traditional treatment strategies remain inadequate indicating that alternative therapy options need to ... -
Cancer Associated Fibroblasts Have Phenotypic and Functional Characteristics Similar To The Fibrocytes That Represent A Novel Mdsc Subset
(Taylor & Francis Inc, 2015)Circulating fibrocytes were reported to represent a novel myeloid-derived suppressor cell (MDSC) subset and they were also proposed to be involved in the tumor immune escape. This novel fibrocyte subset had a surface ... -
Cancer Burden In Four Countries Of The Middle East Cancer Consortium (Cyprus; Jordan; Israel; Izmir (Turkey)) With Comparison To The United States Surveillance; Epidemiology And End Results Program
(Elsevier Sci Ltd, 2016)It is important that population-based cancer registries provide accurate and reliable data for public health purposes. These data are essential data for planning of cancer control and prevention. In this study, we examined ... -
Cancer Trends and Incidence and Mortality Patterns in Turkey
(Oxford Univ Press, 2011)Cancer incidence and mortality rates have been increasing in Turkey as most of the developing countries. Besides socioeconomic factors, one of the most prominent attributes of developing countries is the dissimilarity of ... -
Comparatıve Analysıs of Myeloıd-Derıved Suppressor Cells From Blood and Spleen in Gastrıc and Pancreatıc Cancer
(Sağlık Bilimleri Enstitüsü, 2022-07-29)Under physiological conditions, development and maturation of the myeloid cells take place in the bone marrow. In case of chronic inflammatory disorders such as cancer, production of chemokines, growth factors, and cytokines ... -
Cyberknife Synchrony® Solunum Takip Sisteminin Polimer Jel Dozimetre ile Üç Boyutlu Performans Analizi
(Kanser Enstitüsü, 2017-02-20)ŞAHİN, M. C. Three Dimensional Performance Analysis Of Cyberknife Synchrony® Respiratory Tracking System Using Polymer Gel Dosimeter. Hacettepe University Institute of Health Sciences, Thesis in Radiotherapy Physics ... -
CyberKnife® Robotik Radyocerrahi Cihazında MAGIC Polimer Jel Dozimetre İle Küçük Alan Dozimetrisinin İncelenmesi
(Kanser Enstitüsü, 2018)ENKAVİ, M.F. Investigation of Small Field Dosimetry with MAGIC Polymer Gel Dosimeter in CyberKnife® Robotic Radiosurgery Device. Hacettepe University Institute of Health Sciences, MSc. Thesis in Radiotherapy Physics Program, ... -
Cyberknife® ve Varian RapidArc® TrilogyTM Cihazında Üç Boyutlu Uzaysal Fraksiyone Grid Terapi Doz Karakteristiklerinin Karşılaştırılması
(Kanser Enstitüsü, 2020-12). Lattice therapy is an innovative method to increase the effectiveness of radiotherapy by delivering a high dose to the target volume irradiated through small spaces in one or more fractions.In this study, we investigated ... -
Cytoreductive Surgery For Intestinal Cancer Patients Metastatic To Ovaries Presenting As Primary Ovarian Cancer
(Akad Doktorlar Yayınevi, 2016)Colorectal cancer accounts for one third of non-genital tumors metastasize to the ovaries. We aimed to investigate the role of cytoreductive surgery in colon and small intestinal cancer patients with adnexal metastases, ... -
Deep Vein Thrombosis Following Non-Myeloablative Allogeneic Stem Cell Transplantation: Presentation of Three Cases and Literature Review
(Galenos Yayınevi, 2013)The incidence of deep vein thrombosis (DVT) after non-myeloablative (NMA) allogeneic stem cell transplantation (allo-SCT) is unknown. In addition, very few studies on the predisposing factors for DVT post SCT have been ... -
Determinants of New-Onset Atrial Fibrillation in Patients Receiving Crt Mechanistic Insights From Speckle Tracking Imaging
(Elsevier Science Inc, 2016)OBJECTIVES The aim of this study was to investigate the factors associated with the development of atrial fibrillation (AF) and to examine the impact of these factors for long-term outcome after cardiac resynchronization ... -
Effect of Zoledronic Acid on Rats' Tissue Sdf-1 Expression
(Akad Doktorlar Yayınevi, 2016)Zoledronic acid has been shown to inhibit cancer cell proliferation, metastasis and induce cancer cell apoptosis. Stromal Derived Factor-1 (SDF-1) is a chemokine that has been reported to be expressed markedly high in the ... -
Efficacy of Adjuvant Aromatase Inhibitor In Hormone Receptor-Positive Postmenopausal Breast Cancer Patients According To The Body Mass Index
(Cancer Research UK, 2012)Background: Increased adiposity may trigger signalling pathways that induce aromatase expression. As aromatase inhibitors exert their effects by blocking the aromatase enzyme, higher body mass index (BMI) can reduce the ... -
Efficacy of Sorafenib In Advanced Differentiated and Medullary Thyroid Cancer: Experience In A Turkish Population
(Dovepress, 2014)Purpose: Chronic otitis media with effusion (OME) is the leading cause of hearing loss during childhood. In bacterial etiology of OME, the most frequent pathogens responsible are Haemophilus influenzae followed by Streptococcus ... -
Evaluation of Metadherin Expression in Breast Cancer
(Sağlık Bilimleri Enstitüsü, 2018)Metadherin gene (MTDH/ AEG-1/ Lyric) encodes a 582- aminoacid protein, metadherin (MTDH), which is almost undetectable by immunohistochemistry in normal breast tissue. MTDH expression is markedly increased in breast cancer ... -
Farklı Aktivasyon Basamaklarına İlerletilen Yardımcı T Hücrelerinde Adezyon ve Migrasyon Mekanizmalarının İncelenmesi
(Kanser Enstitüsü, 2020)When different analog T lymphocyte profiles are examined in cancer and chronic infections, these cells can be divided into two subgroups with functional and dysfunctiononal characterization. Naive T lymphocytes which are ...