Browsing Biyomühendislik Bölümü Tez Koleksiyonu by Type "info:eu-repo/semantics/doctoralThesis"
Now showing items 1-20 of 22
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3 Boyutlu Yazıcı ile Metakrilatlanmış Jelatin/PRP Hidrojel ve Mezenkimal Kök Hücre İçeren Osteokondral Gradyan Sistemlerin Hazırlanması ve in-Vitro Etkinliklerinin Belirlenmesi
(Fen Bilimleri Enstitüsü, 2019)The aim of the presented doctoral thesis is to develop a gradient hydrogel system which loaded adipos tissue derived stem cells (AdMSCs) by using photoactivated platelet-rich plasma (PRP) gradient and 3D bioprinting method ... -
Biyodizel atığı ham gliserolden rekombinant Pichia pastoris mayası ile laktik asit üretimi
(Fen Bilimleri Enstitüsü, 2017-06-20) -
Biyofiziksel ve Biyokimyasal Uyaranlarla Desteklenmiş Doku İskeleleri ile Mezenkimal Kök Hücrelerin Osteojenik Farklılaşmasının İncelenmesi
(Fen Bilimleri Enstitüsü, 2014)The aim of this study is to investigate the osteogenic differentiation potential of mesenchymal stem cells in the presence of biophysical and biochemical stimulants by using different biomaterials. For this purpose, ... -
Cytochrome C Purıfıcatıon with Surface Imprinted Bacterial Cellulose Nanofibers
(Fen Bilimleri Enstitüsü, 2014)In the present study, cytochrome c imprinted bacterial cellulose (Cyt c-MIP)nanofibers were prepared for the purification and recognition of cytochrome c viasurface imprinting approach. N-methacryloyl-L-histidine methyl ... -
Dejeneratif Kıkırdak Hasarlarına Yönelik Enjekte Edilebilir Hidrojel Sistemlerinin Geliştirilmesi ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2018)Cartilage degeneration is a pathology that develops over time, beginning with the softening of the cartilaginous gland and then completely disappearing. It may be due to trauma, as well as diseases such as osteoarthritis, ... -
Doku Mühendisliğinde Malzemeye Ve Hücresel Özelliklere Ait İmgelerin Görüntü İşleme Teknikleri İle Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2018)Image processing techniques are frequently used to obtain quantitative information from images of various imaging techniques. Image analysis in tissue engineering and cell biology is a time-consuming and specialized process. ... -
DÜŞÜK MALİYETLİ BİR RAMAN SPEKTROSKOPİ SİSTEMİ TASARIMI, KURULUMU VE NANOYAPILAR İLE BİRLİKTE TANIDA KULLANIMI
(Fen Bilimleri Enstitüsü, 2017-07-17)When the light interacts with the substance, the photons that form the light may be absorptive or dispersible or may not interact with the material and may pass directly through the material. If the energy of the incident ... -
Hücre Tabakası Mühendisliğinde Kalınlık ve Vaskülerizasyon Problemlerine Yönelik Stratejilerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)In the context of tissue engineering studies, various biomaterials, cells and biosignal molecules have been used to repair and replace diverse tissues either alone or in combination, namely to produce tissue-engineered ... -
Hücrelerinden Arındırılmış Miyokardiyal Doku İle Hücre Tabakası Destekli Kalp Yaması Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019-02)The aim of this thesis is to produce a heart patch by combining cardiovascular cell sheet and decellularized myocardial extracellular matrix (ECM). In the study, two innovative approaches of tissue engineering, ‘‘cell sheet ... -
Investigation And Assessment Of Mirror Neuron Activity For Rehabilitation Purposes
(Fen Bilimleri Enstitüsü, 2017)Mirror neurons, discovered on prefrontal cortex and subsequently on inferior parietal lobule of macaque monkey, are a class of neurons that become activated with both performing an action and observing the same action. ... -
İn Vitro Diyabetik Ülser Modelinde Fotostimülasyonun Yara İyileşmesi Üzerine Etkisinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2022-09-26)This study was supported by Hacettepe University Scientific Research Projects Coordination Unit (BAP) within the scope of the PhD Thesis Project (FDK-2019-18072) titled "Examination of the Effect of Photostimulation on ... -
Kanser Hücrelerinin Aptamer ve Antibadi Taşıyan Manyetik Nanopartiküller ile Hedeflenmesi
(Fen Bilimleri Enstitüsü, 2014)Within the context of this thesis, developing of an early diagnosis nanoparticular system in order to detect and image human breast cancer cell line of MDA MB 231 is aimed. In this regard, gold coated superparamagnetic ... -
Kanser Tedavisinde Gen Susturulması İçin Hyalüronik Asit-Polietilenimin Taşıyıcı Sisteminin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)Target-specific delivery of small interfering siRNAs in cancer treatment is one of today's leading research topics. Within the scope of the thesis, effective transport of siRNAs via hyaluronic acid (HA) receptor was carried ... -
Karaciğer Tümörlerinin Tedavisinde Uygulanacak Y-90 Mikrokürelerin Aktivite Miktarlarının Hastaya Özgü Modelleme İle Belirlenmesi İçin Yöntem Geliştirilmesi ve Yöntemin Standardize Edilmesi
(Fen Bilimleri Enstitüsü, 2019)Yttrium-90 (Y-90) microsphere treatment is the internal radionuclide treatment through administration of Y-90 loaded microspheres to the tumor microcirculation via the relevant branch of the hepatic artery feeding the ... -
Mikrobiyal Hava Toplayıcı ve Okuyucu Sistemi Tasarımı ve Prototip Üretimi
(Fen Bilimleri Enstitüsü, 2015)The detection of air purifier or air pollution is very important step to take necessary precautions to prevent infections. Nowadays, partical measuring and passive air sampling methods are widely used to detect air pollution ... -
Nerve Guidance Conduit Application Of Magnesium Alloys
(Fen Bilimleri Enstitüsü, 2019)Surgery is insufficient for peripheral nerve injuries larger than 5 mm. Function loss and scar formation occur as a result of slow healing rate and inflammation cells filling the damaged gap. Therefore, isolation of damaged ... -
Osteokondral Doku Mühendisliğinde Tabakalı Hibrit Yapıların Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023)In this study, ceramic and decellularized bone inserted Poly(glycerol sebacate) (PGS) elastomer-based scaffolds for use in bone tissue engineering and osteochondral tissue engineering applications were designed, produced ... -
Poli(Poliol)Sebakat Bazlı Biyobozunur Elastomerlerin Sentezi ve Jiro Eğrilmiş Fiber Destekli Hidrojel Doku İskelelerinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)Poly(polyol) sebacate (PPS) based polymers are promising polymers in biomedical and tissue engineering field, thanks to tunable mechanical properties and having biodegradable and biocompatible features. However, difficult ... -
POLİMERİK NANOPARTİKÜL FLORESAN PROBLARLA BAKTERİYAL FİLMLERİN İN-VİVO GÖRÜNTÜLENMESİ
(Fen Bilimleri Enstitüsü, 2017-06)The aim of this theses is to synthesize polymeric nanoparticle fluorescence probes in order to be used in in-vitro and in-vivo imaging of Staphylococcus aureus and the biofilms produced by these bacteria. 1ml THF solution ... -
Sklera Hasarlarının Rekonstruksiyonunda Otojenik, Allojenik Ve Zenojenik Greftlerin Karşılaştırılması: Yeni Bir Otolog Yaklaşım “Trombositten Zengin Fibrin Membran”
(Fen Bilimleri Enstitüsü, 2018)The purpose of the presented thesis was to compare the effects of xenogenic, allogenic and autogenic graft materials on scleral healing in the repair of scleral tissue damage. For this purpose, scleral tissue damage model ...