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12/15-Lipoxygenase Inhibition or Knockout Reduces Warfarin-Associated Hemorrhagic Transformation After Experimental Stroke
(Lippincott Williams & Wilkins, 2017)
Background and Purpose For stroke prevention, patients with atrial fibrillation typically receive oral anticoagulation. The commonly used anticoagulant warfarin increases the risk of hemorrhagic transformation (HT) when a ...
Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis In Two Pairs Of Identical Twins
(Comenius Univ, 2012)
The most common pathology in adult patients with temporal lobe epilepsy is hippocampal sclerosis (HS), the etiology of which is not clear. There is a conflicting evidence in literature regarding whether HS is genetic or ...
Capillary Pericytes Express Α-Smooth Muscle Actin, Which Requires Prevention of Filamentous-Actin Depolymerization For Detection
(eLife Sciences, 2018)
Recent evidence suggests that capillary pericytes are contractile and play a crucial role in the regulation of microcirculation. However, failure to detect components of the contractile apparatus in capillary pericytes, ...
Data Of Ascending Cortical Vein Occlusion Induced Spreading Depression
(Elsevier, 2018)
The data presented in this article are related to the research article entitled “Microembolism of single cortical arterioles can induce spreading depression and ischemic injury; a potential trigger for migraine and related ...
Mutation Analysis Of The Pink1 Gene In 391 Patients With Parkinson Disease
(Amer Medical Assoc, 2008)
Objectives: To determine the frequency, distribution, and clinical features of Parkinson disease (PD) with PINK1 mutations. Design: Retrospective clinical and genetic review. Setting: University hospital. Patients: We ...
Mutations in A Human Robo Gene Disrupt Hindbrain Axon Pathway Crossing and Morphogenesis
(Amer Assoc Advancement Science, 2004)
The mechanisms controlling axon guidance are of fundamental importance in understanding brain development. Growing corticospinal and somatosensory axons cross the midline in the medulla to reach their targets and thus form ...
Bilateral Temporal Bone Xanthomas in Type II Hypercholesterolemia
(Turkish Neurosurgical Soc, 2010)
We present a very rare case of intracranial xanthoma with bilateral temporal bone involvement. The lesion caused destruction and remodelling in mastoid air cells. On the right side, cerebellar compression was obvious. The ...
Default Mode Network Connectivity Is Linked to Cognitive Functioning and Csf A Beta(1-42) Levels In Alzheimer'S Disease
(Elsevier Ireland Ltd, 2016)
Background: Changes in the default mode network (DMN) activity are early features of Alzheimer's disease (AD) and may be linked to AD-specific A beta pathology. Methods: Cognitive profiles; DMN connectivity alterations; ...
Neuro-Ophthalmologic Findings In Humans With Quadrupedal Locomotion
(Informa Healthcare, 2012)
Purpose: To report the neuro-ophthalmologic findings in four patients from the same family with cerebellar ataxia, mental retardation, and dysequilibrium syndrome (CAMRQ) 2 associated with quadrupedal locomotion. Method: ...
Nuclear Expansion And Pore Opening Are Instant Signs Of Neuronal Hypoxia And Can Identify Poorly Fixed Brains
(Nature Publishing Group, 2018)
The initial phase of neuronal death is not well characterized. Here, we show that expansion of the nuclear membrane without losing its integrity along with peripheralization of chromatin are immediate signs of neuronal ...