Başlık için Eczacılık Meslek Bilimleri Bölümü listeleme
Toplam kayıt 336, listelenen: 288-307
-
Synthesis And Biological Evaluation Of New Tricyclic Dihydropyridine Based Derivatives On Potassium Channels
(2016)The present study reports a microwave-assisted method for the synthesis of twelve novel tricyclic 1,4-dihydropyridine derivatives in which dimethyl-substituted cyclohexane and / or tetrahydrothiophene rings are fused to ... -
Synthesis, Structural Characterization and Myorelaxant Activity of 4-Naphthylhexahydroquinoline Derivatives Containing Different Ester Groups
(Serbian Chemical Soc, 2016)The present study reports the synthesis, structural characterization and myorelaxant activity evaluation of a series of 16 novel 4-naphthylhexahydroquinoline derivatives. The compounds were achieved by one-pot microwave-assisted ... -
Synthesıs of Condensed 1,4-Dıhydropyrıdıne Derıvatıves and Evaluatıon of Theır Calcıum Channel Modulatıng and Antıoxıdant Actıvıtıes
(Sağlık Bilimleri Enstitüsü, 2014)In this study, study, a pharmacophore model based on calcium channel blocker ligands was generated by LigandScout and nineteen 2-(methacryloyloxy)ethyl 4-aryl-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate ... -
Sıçan Izole Mezenter Arterinde Kalsiyumsuz Ortamda Elektriksel Alan Uyarısı Ile Elde Edilen Kasılmaların Mekanizmasının Incelenmesi
(Sağlık Bilimleri Enstitüsü, 2014)In the present study, we aimed to examine the effect of blockade of L-type calcium channels (LTCC) and in addition the removal of extracellular calcium, on EFS-induced relaxations in rings of rat mesenteric artery. EFS (30 ... -
Sıçanlarda Adeno İlişkili Viral Vektör Aracılı Gerçekleştirilen Nigral ve Hipokampal Alfasinükleinopati Modelinde Rapamisinin Etkileri
(Sağlık Bilimleri Enstitüsü, 2018)Çınar, E., Effects of Rapamycin In A Rat Model Of Adeno Associated Viral Vector Mediated Nigral and Hippocampal Alpha-synucleinopathy, Hacettepe University Graduate School of Health Sciences, Pharmacology Programme Doctor ... -
Sıklıkla Kullanılan Bitkisel Ürünlerin İlaçlar İle Olası Etkileşmelerinin Eczacılar Tarafından Farkındalıklarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019-09-19)The use of herbal medicines and nutritional supplements has been increased dramatically in many parts of the world. Since many herbal products has been sold over the internet. It is difficult to evaluate the extent of the ... -
Şizofreni ve Benzeri Psikotik Bozukluk Tanısı Almış Hastalara Taburculuk Döneminde İlaç Tedavisine Uyuncunu Arttırmaya Yönelik Olarak Verilen İlaç Eğitiminde Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2017-12-18)The inability to achieve full compliance with drug treatment during the post-discharge period with exacerbations in the illness in patients with schizophrenia and other psychotic disorders is a major problem for the patients ... -
Taxonomic Notes on the Genus Chaenorhinum (Plantaginaceae) in Turkey
(Univ Zagreb, Fac Science, Div Biology, 2018)Chaenorhinum gerense is an eastern Mediterranean species with rare distribution and a large variety in plant and seed morphology. In this study, the accuracy of the taxonomic status of this species, which was initially ... -
The Effect Of Quercus Coccifera L. Extract On The Necrosis Of Random-Pattern Skin Flaps In Rats
(2019)Aim: Ischemia-reperfusion injury is an important cause of flap loss. We investigated effects of Quercus coccifera L. extract known to have anti-oxidant and anti-inflammatory activity on skin flap viability. Methods: Eighteen ... -
The Effects of Di(2-Ethylhexyl)Phthalate on Rat Liver in Relation to Selenium Status
(Wiley-Blackwell, 2014)This study was performed to determine the hepatotoxicity of di(2-ethylhexyl)phthalate (DEHP) in relation to selenium status. In 3-week-old Sprague-Dawley rats, selenium deficiency was induced by a 0.05 selenium mg/kg. A ... -
The Effects of Fenvalerate on Hepatic and Cerebral Xenobiotic Metabolizing Enzymes in Selenium and/or Iodine Deficient Rats
(2016)Objective(s): Particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. Fenvalerate is a pyrethroid insectide used in agriculture ... -
The Evaluation Of Sterile Solutions Of Ilwensisaponin A And C From Verbascum Pterocalycinum Var. Mutense Hub.-Mor. On Antiviral, Antinociceptive And Anti-Inflammatory Activities
(2019)Antiviral, antinociceptive and anti-inflammatory activities of the 1% sterile solutions of Ilwensisaponin A and C isolated from the methanolic extract of the flowers of Verbascum pterocalycinum var. mutense Hub.-Mor. were ... -
The Inhibitory Effects Of Isolated Constituents From Plantago Major Subsp. Major L. On Collagenase, Elastase And Hyaluronidase Enzymes: Potential Wound Healer
(2020)Plantago major L. which is a medicinal plant with important biological activities, commonly used as traditional medicine. Potential inhibitory activities of the aqueous extract and three isolated constituents calceorioside ... -
The Protectıve Role of Escıtalopram on Impared Hıppocampal Neuroplastıcıty Durıng Rem Deprıvatıon
(Sağlık Bilimleri Enstitüsü, 2013)Sleep disorders are mostly associated with psychiatric problems like depression, anxiety disorders, etc. and are thought to be the underlying cause of cognitive deficits observed in these patients. It has been shown that ... -
The Role and Importance of Dorsal And Ventral Hıppocampal Catecholamınergıc Innervatıons in Socıal Memory of Rats
(Sağlık Bilimleri Enstitüsü, 2022)This study aims to investigate the role and importance of the catecholaminergic innervations in the dorsal (DH) and ventral hippocampus (VH) in social memory of rats. Female Wistar rats were injected bilaterally with ... -
The Roles Of Valerenic Acid On Bdnf Expression In The Sh-Sy5Y Cell
(Elsevier Science Bv, 2018)The roots of Valeriana officinalis L. (Valerianaceae) are used for treating sleep disorders and/or mild nerve tension. The effect of valerenic acid on brain-derived neurotrophic factor (BDNF) has not yet been studied, ... -
Three Acylated Flavone Glycosides From Sideritis Ozturkii Aytac & Aksoy
(Pergamon-Elsevier Science Ltd, 2004)From the aerial parts of Sideritis ozturkii, three new flavonoids, chrysoeriol 7-O-[2"'-O-calieoyl-6"'-O-acetyl-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucopyranoside], chrysoeriol 7-O-[2"'-O-cafeoyl-beta-O-glucopyranosyl-(1 ... -
Tiroid Hücrelerinde Bisfenol A’nın Toksik Etkileri ve Selenyum Bileşiklerinin Koruyucu Rolünün Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)Bisphenol A (BPA) is a chemical compound that is used in the production of polycarbonates and epoxy resins. Humans are widely exposed to this compound by oral, inhalation and dermal routes in daily life. It is known to ...