Browsing Eczacılık Meslek Bilimleri Bölümü by Title
Now showing items 190-209 of 335
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Lavandula stoechas L. subsp. stoechas Üzerinde Biyolojik Aktivite Rehberli Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2023)Lavandula stoechas L. subsp. stoechas known as “karabaş otu” is used for diabetes and central nervous system disorders. This thesis focuses on scientifically validating the traditional usage of L. stoechas subsp. stoechas ... -
Leadership and Healthcare Services
(Intech Europe, 2017)The reasons why organizations make changes in various fields, especially in their structure, include various changing situations such as globalization, increasing awareness in human rights and employee rights, developments ... -
Low Dose Simvastatin Induces Compositional, Structural and Dynamic Changes in Rat Skeletal Extensor Digitorum Longus Muscle Tissue
(Portland Press Ltd, 2010)Statins are commonly used drugs in the treatment of hypercholesterolaemia. There are many adverse effects of statins on skeletal muscle, but the underlying mechanisms remain unclear. In the present study, the effects of ... -
Low Doses Of Selenium Specifically Stimulate The Repair Of Oxidative Dna Damage In Lncap Prostate Cancer Cells
(Informa Healthcare, 2012)Epidemiological studies have demonstrated an inverse relationship between selenium (Se) intake and cancer incidence and/or mortality. However, the molecular mechanisms underlying the cancer chemopreventive activity of Se ... -
Luddin Type Anthraquinone Glycosides from Putoria Calabrica
(Pharmaceutical Soc Japan, 2002)Two new lucidin type anthraquinone glycosides, putorinoside A (1) and putorinoside B (2) were isolated from Putoria calabrica, in addition to two known anthraquinone glycosides, lucidin 3-O-beta-glucopyranoside (3) and ... -
Lycopene Restores Trace Element Levels in Ochratoxin A-Treated Rats
(Inst Medical Research & Occupational Health, 2017)This study was designed to investigate the in vivo effects of ochratoxin A (OTA) and/or lycopene on the levels of selenium, zinc, and copper in the liver, kidneys, and testes of male Sprague-Dawley rats. The rats were ... -
Medikal Onkoloji Polikliniğinde Tedavi Alan Hastalarda Hedefe Yönelik Tedavi ile İlgili Sorunların Belirlenmesi ve Önlenmesinde Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2016)Cancer is defined as uncontrolled growth of cells, which can invade and spread to other organs and tissues of the body. The primary goal in cancer treatment is to eradicate the cancer. Cancer treatments can be classified ... -
Melazma tedavisinde yeni yaklaşımlar ve olası toksik etkilerinin in vitro olarak değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2023)Melasma is a chronic, acquired disease that results in the accumulation of brown or gray-brown melanin pigment in the epidermis layer and/or dermis layer, especially in areas where the body is more exposed to sunlight, ... -
Mermer İşçilerinde Genotoksik Etki Mekanizmalarının ve Oksidatif Stres ile İlişkili Değişikliklerin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Workers working in marble processing plants are exposed to high levels of respirable marble dust (<10 μm) in processes such as cutting, polishing, shaping. Marble dust is mainly composed of calcium carbonate and contains ... -
Metal Geri Dönüşüm Sektörü Çalışanlarında Kurşun Maruziyetinin Neopterin Düzeylerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2023)Muhammetli S., The Effect of Lead Exposure on Neopterin Levels in Metal Recycling Industry Workers, Hacettepe University Graduate School of Health Sciences Pharmacy Department of Pharmaceutical Toxicology Program Master of ... -
Metforminin Bazı Kemoterapötik İlaçlarla Etkileşmesinin İn Vitro Olarak Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2016-12-29)Metformin is an oral antidiabetic drug widely used in the treatment of type 2 diabetes mellitus. It is stated that diabetes patients have a higher risk of developing different pathologies including cancer than healthy ... -
Metforminin Sitotoksik, Apoptotik ve Genotoksik Etkilerinin İn Vitro Değerlendirilmesi.
(Sağlık Bilimleri Enstitüsü, 2018)Metformin is a biguanide derivative widely used in the treatment of diabetes mellitus. Recent studies have shown the anticancer properties of metformin. The possible mechanisms of anticancer effects of metformin have ... -
Microwave-Assisted Synthesis Of Condensed 1,4-Dihydropyridines As Potential Calcium Channel Modulators
(Scientific Technical Research Council Turkey-Tubitak, 2015)This study reports the design, synthesis, and calcium channel modulatory activity evaluation of a series of 14 novel fused 1,4-dihydropyridine derivatives. The molecular design of the compounds was based on modifications ... -
Modulation Of The Poly (Adp-Ribose) Polymerase Inhibitor Response And Dna Recombination In Breast Cancer Cells By Drugs Affecting Endogenous Wild-Type P53
(Oxford Univ Press, 2014)Synthetic lethal interactions between poly (ADP-ribose) polymerase (PARP) and homologous recombination (HR) repair pathways have been exploited for the development of novel mono-and combination cancer therapies. The tumor ... -
Molecular Modeling-Based Delivery System Enhances Everolimus-Induced Apoptosis In Caco-2 Cells
(2019), Several studies have shown that the mammalian target of rapamycin (mTOR) inhibitor; everolimus (EV) improves patient survival in several types of cancer. However, the meaningful efficacy of EV as a single agent for the ... -
Monoamin Oksidaz İnhibitörü Etki Göstermesi Beklenen Yeni Hidrazon Bileşiklerinin Sentezi, Moleküler Modellemesi ve MAO-A /MAO-B Seçiciliklerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2022-02-11)In this study, 16 compounds were synthesized as 2 compounds (Compound 1 and 2) of N'-substitutedbenzylidene-2-(5-chloro-2-benzoxazolinon-3-yl)acetohydrazide, 6 compounds (Compounds 3-8) of 3-(substituted ...