Browsing Eczacılık Teknolojisi Bölümü Makale Koleksiyonu by Issue Date
Now showing items 1-20 of 35
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Estimation Of Aqueous Distributional Spaces In The Dual Perfused Rat Liver
(Cambridge Univ Press, 2000)1. The aim of this study was to estimate the aqueous distributional spaces of the liver as a function of the route of input: portal vein (PV) versus hepatic artery (HA). 2. Studies were performed in the in situ single (PV) ... -
High-Performance Liquid Chromatographic Determination Of Amphotericin B In A Liposomal Pharmaceutical Product And Validation Of The Assay
(Preston Publications Inc, 2000) -
Thrombus Localization By Using Streptokinase Containing Vesicular Systems
(Taylor & Francis Ltd, 2006)Our research focused on the preparation of vesicular drug delivery systems, such as liposomes, noisomes, and sphingosomes, for achieving slow release of entrapped proteins in the circulation to increase half-life, to mask ... -
Development Of A Peptide-Containing Chewing Gum As A Sustained Release Antiplaque Antimicrobial Delivery System
(Springer, 2007)The objective of this study was to characterize the stability of KSL-W, an antimicrobial decapeptide shown to inhibit the growth of oral bacterial strains associated with caries development and plaque formation, and its ... -
Preparation and in Vitro Evaluation Of Bfgf-Loaded Chitosan Nanoparticles
(Taylor & Francis Inc, 2007)The objective of our study was to prepare and characterize basic fibroblast growth factor (bFGF)-loaded nanoparticles. Protein-loaded chitosan nanoparticles were obtained by ionotropic gelation process based on the interaction ... -
The Operational Multiple Dosing Half-Life: A Key To Defining Drug Accumulation In Patients And To Designing Extended Release Dosage Forms
(Springer/Plenum Publishers, 2008)Half-life (t (1/2)) is the oldest but least well understood pharmacokinetic parameter, because most definitions are related to hypothetical 1-compartment body models that don't describe most drugs in humans. Alternatively, ... -
Preparation and Characterization of Salmon Calcitonin-Biotin Conjugates
(Springer, 2008)This study was performed to prepare and characterize the biotinylated Salmon calcitonin (sCT) for oral delivery and evaluate the hypocalcemic effect of biotinylated-sCTs in rats. Biotinylated sCTs was characterized by using ... -
A Quadruped Study on Chitosan Microspheres Containing Atorvastatin Calcium: Preparation, Characterization, Quantification And In-Vivo Application
(Pharmaceutical Soc Japan, 2010)Atorvastatin is commonly used as a cholesterol lowering agent in patients. Recently, the neuroprotective effects of atorvastatin became the focus of many research studies. In this study, we have formulated chitosan ... -
Design And Characterization Of Nanocrystal Formulations Containing Ezetimibe
(Pharmaceutical Soc Japan, 2011)Ezetimibe is a lipid-lowering compound that selectively inhibits the absorption of cholesterol and related phytosterols from the intestine As ezetimibe is almost Insoluble in water, its bioavailability is too low to be ... -
Two Percent Chitosan Mouthwash: A Microbiological And Clinical Comparative Study
(Elsevier Taiwan, 2012)Background/purpose: The aim of this study was to evaluate the microbiological and clinical effects of a chitosan (CH) mouth rinse on plaque inhibition. Materials and methods: Thirty-six healthy participants were recruited. ... -
Long-Circulating Peg-Pe Micelles Co-Loaded with Paclitaxel and Elacridar (Gg918) Overcome Multidrug Resistance
(Taylor & Francis Ltd, 2012)Overexpression of drug efflux pump P-gp is one of the major reasons to cause multidrug resistance (MDR). To overcome P-gp mediated MDR, modulators, so called P-gp inhibitors, can be used to block efflux pump activity. ... -
Preparation and In Vitro/In Vivo Evaluation of Microparticle Formulations Containing Meloxicam
(Springer, 2012)In this study, we have formulated chitosan-coated sodium alginate microparticles containing meloxicam (MLX) and aimed to investigate the correlation between in vitro release and in vivo absorbed percentages of meloxicam. ... -
An Overview on Dry Eye Treatment: Approaches for Cyclosporin A Delivery
(2012)Dry eye syndrome (DES, Keratoconjunctivitis sicca) is a common disorder of the tear film caused by decreased tear production or increased evaporation. Changes in tear composition also promote inflammation on the ocular ... -
Characterization Of Protein And Peptide Binding To Nanogels Formed By Differently Charged Chitosan Derivatives
(2013)Chitosan (Chi) is a natural biodegradable cationic polymer with remarkable potency as a vehicle for drug or vaccine delivery. Chi possesses multiple groups, which can be used both for Chi derivatization and for particle ... -
Dendrimeric Systems And Their Applications In Ocular Drug Delivery
(2013)Ophthalmic drug delivery is one of the most attractive and challenging research area for pharmaceutical scientists and ophthalmologists. Absorption of an ophthalmic drug in conventional dosage forms is seriously limited ... -
Effect of Locally Applied Transforming Growth Factor Beta3 on Wound Healing and Stenosis Development in Tracheal Surgery
(Daedalus Enterprises Inc, 2014)BACKGROUND: Tracheal stenosis constitutes one of the most frequently seen problems in thoracic surgery. Although many treatment modalities to prevent fibroblast proliferation, angiogenesis, or inflammation that causes ... -
Effect of Topically Applied Sildenafil Citrate on Wound Healing: Experimental Study
(Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, 2014)Wound healing is a complex process that necessitates organization of different cell types and several signalling molecules. The aim of this study is to evaluate the effect of different concentrations of sildenafil citrate, ... -
Determination Of Regional Intestinal Permeability Of Diclofenac And Metoprolol Using A Newly-Developed And Validated High Performance Liquid Chromatographic Method
(Pharmacotherapy Group, 2015)Purpose: To develop a simple and rapid reversed-phase high performance liquid chromatographic (HPLC) method with UV detection for the simultaneous determination of diclofenac, metoprolol tartrate, phenol red and propyl ...
