Dosya Biçimi"Bilimsel Araştırma Projeleri KB" Biyomühendislik için listeleme
Toplam kayıt 29, listelenen: 1-20
-
Adenozin Tayinine Yönelik Optik Temelli Nanosensörlerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2022-01)In this thesis, a novel measurement method is proposed to measure the level of adenosine nucleoside which is a significant molecule utilized as a direct or indirect indicator to detect diseases such as neurodegenerative ... -
Akciğer Havayolu Modellemesine Yönelik Oluşturulan Deselülerize Doku İskeleleri ile 3b Hücre Kültür Sistemlerinin Kurulması
(Fen Bilimleri Enstitüsü, 2021)The lungs have the task of providing the necessary oxygen for the cells and carrying out the carbon dioxide formed as a result of metabolic events. During this process, which we call breathing, the lungs encounter many ... -
Anti-Her2 SCFV Antikor Fragmanının Escherichia coli Bakterisinde Üretim Bölgesinin Optimizasyonu
(Fen Bilimleri Enstitüsü, 2022)Antibodies and antibody fragments are used in the diagnosis, imaging, and target-specific treatments of various diseases such as cancer and viral infections. It also has an important place in combating infectious diseases. ... -
Fotostimülasyonun 2 ve 3 Boyutlu in vitro Hiperglisemik Modellerde İnsan Dermal Fibroblast, Keratinosit ve Endotel Hücreleri Üzerindeki Etkinliğinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2024)This study is supported by the Scientific Research Projects Coordination Unit (BAP) of Hacettepe University as part of the comprehensive research project titled "Investigation of the Effectiveness of Photostimulation in ... -
Geliştirilen Üç Boyutlu Böbrek Proksimal Tübül Modelinde Nefrotoksisite Değerlendirmesi
(Fen Bilimleri Enstitüsü, 2023)Acute kidney injury (AKI) is an important health problem causes the death of 2 million people worldwide every year with high morbidity and mortality. One of the important causes of AKI is drug-induced nephrotoxicity. After ... -
Hasarlı Omurilik Onarımı İçin Hücre Destekli Enjekte Edilebilir İpek Fibroin Mikrotaşıyıcıların Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023-09)According to the data of the World Health Organization (WHO), spinal cord injuries affect between 250,000 and 500,000 people every year. In current clinical practice, there is no treatment method that can completely ... -
Havayolu Modellemesi Amaçlı Tasarlanan Mühendislik Ürünü 3B Hücre Kültür Sistemlerinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2022-06)Chronic airway diseases have a complex set of mechanisms in which environmental and genetic factors play a role. It is very important to study the molecular pathologies of these diseases and to establish suitable cellular ... -
Hücre Ölüm Yolaklarının Tespiti İçin Kağıt Tabanlı Biyosensör Tasarımı
(Fen Bilimleri Enstitüsü, 2021)The aim of the presented thesis, a paper-based biosensor design has been designed to be used in the detection of early (extrinsic pathway) and late (instrinsic pathway) stages of apoptosis. In the study, in order to ... -
İlaç Araştırmaları İçin 3-Boyutlu Mikroakışkan Damar Modelinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)There is a need for a 3-dimensional (3D) vessel model that can be used to simulate in vivo vessel physiology, anatomy, and blood flow-induced fluid tension force that can be used in the investigation of vascular diseases, ... -
Kemik Tümörlerinde Lipozomal Kannabinoidlerin Reseptör Aracılı Antiproliferatif ve Apoptotik Etkilerinin Araştırılması
(Fen Bilimleri Enstitüsü, 2022-12-30)Primary osteosarcoma is the most common osteogenic tumor in children and adolescents, known with its rapid metastasis. The limitations of the treatment approaches applied in the clinic and the side effects observed in ... -
Kompozit İnterferans Vidaların Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2020)The anterior cruciate ligament is one of the structures that connect the femur and tibia bones in the knee joint. This ligament, which is very important for the normal functioning of the knee, is the most important structure ... -
Konkanavalin A Baskılanmış Yüzey Plazmon Rezonans Temelli Biyosensörün Hazırlanması
(Fen Bilimleri Enstitüsü, 2022)Within the scope of this thesis, a Concanavalin A imprinted surface plasmon resonance (SPR) biosensor was prepared for the determination of Concanavalin A. At the beginning, the surface of the SPR biosensor chip was modified ... -
Kontrollü Bor Salan Biyobozunur Yara Örtülerinin Geliştirilmesi ve Dermal/Mukozal Rejenerasyonda Kullanımlarının Araştırılması
(Fen Bilimleri Enstitüsü, 2022)The following thesis presents the development of fiber matrices containing boron (B), which has therapeutic effects in wound healing, and montmorillonite (MMT) as nanoclay. These are specifically used in the treatment of ... -
Kornea Doku Mühendisliği İçin Hibrit Biyomateryal Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)The cornea is a transparent structure that covers 1/6 of the eye, has a convex shape, has the task of focusing light and protecting the eye from external influences, and has a major role in vision. Corneal blindness; It ... -
Kurkumin Tayinine Yönelik Yüzey Plazmon Rezonans Temelli Nanosensörlerin Hazırlanması
(Fen Bilimleri Enstitüsü, 2021-12)Herbal ingredients are among the most used products in alternative and complementary medicine. Curcumin, which is obtained from Curcuma longa plant known as Indian saffron or turmeric, has become quite popular in recent ... -
Kurkumin Yüklü Üç Boyutlu Poli(ε-kaprolakton)/Kitosan Nanofibröz Yara Örtü Malzemelerinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023-01)This study was financially supported by Hacettepe University Scientific Research Projects Coordination Unit with a career initiation project titled “Development of Curcumin Loaded Macroporous Antibacterial Three-Dimensional ... -
Menisküs Doku Mühendisliği İçin Hibrit Doku İskelelerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021)Treatment of meniscal tears that occur as aging, injuries, and various traumas is one of the most performed in orthopedic surgery. The increasing rate of meniscal injuries indicates the urgent need to develop an effective ... -
MOLEKÜLER BASKILANMIŞ KRİYOJEL DİSKLERDEN KURKUMİNİN KONTROLLÜ SALIMI
(Fen Bilimleri Enstitüsü, 2021-07)In the drug research area, the way these drugs are administered to patients is as important as developing new molecules for the treatment of diseases. In recent years, controlled drug release systems have been developed ... -
Nanotopografik Fiber Matrikslerin Doku İskelesi Olarak Üretimi ve İn-Vitro Etkinliklerinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2022)This study was funded by Hacettepe University Scientific Research Projects Coordination Unit (BAP) graduate project entitled "Production Of Nanotopographic Fiber Matrices As Tissue Scaffold And Investigation Of Their ... -
Nog Gen İfadesi Susturulmuş Hücrelerin Oluşturulması ve İpek Doku İskeleleri Üzerinde Osteojenik Farklılaşmalarının İncelenmesi
(Fen Bilimleri Enstitüsü, 2020-12-01)This study was funded by Hacettepe University Scientific Research Projects Coordination Unit (BAP) graduate project entitled "Generation of Nog Knockout Cells by CRISPR/Cas9 Mediated Genome Editing and Examination of Their ...
