Rekürren Aftöz Stomatitin Periodontal Hastalıklar ve Helikobakter Pilori Enfeksiyonu ile İlişkisi
Abstract
Recurrent aphthous stomatitis (RAS), characterised by recurrent ulceration, is one of the most common disease of the oral mucosa. Its etiology is unknown but suggested it develops multifactorially. This comparative, controlled and prospective clinical trial was designed to test the hypothesis that H.pylori can play a role in developing RAS and periodontal disease. The dental plaque H.pylori colonisation of 38 patients with RAS and 43 healthy individuals as control were examined. The determination of H.pylori was made according to change in the color of rapid urease test kit which caused the dental plaque isolated with periodontal examination. The periodontal status of patient and control groups was detected with periodontal clinical parameters consisted of periodontal pocket depth, plaque index, gingival index and clinical attachment loss. No any statistically significant difference was found in mean periodontal pocket depth, plaque index, gingival index and clinical attachment loss between patient and control groups ( p >0.05, for all). The rapid urease test results were positive in 34(89.5%) of 38 patients and in 24 (55.8%) of 43 controls. There was statistically significant difference in rapid urease test results between two groups (p>0.002). In both patient and control groups, the mean periodontal pocket depth, plaque index, gingival index and clinical attachment loss values were higher in positive rapid urease test groups compared with negative ones. The difference in periodontal clinical parameters between rapid urease test positive and negative groups was significant in controls (p<0.05). but nonsignificant in patients (p>0.05). With our study, it was demonstrated that H.pylori can be an etiological agent in RAS, additionally this microorganism can lead to periodontal diseases but there is no associatian with periodontal diseases and H.pylori colonisation.