Biyomühendislik Bölümü: Güncel gönderi
Toplam kayıt 101, listelenen: 41-60
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Development Of Beta-Tricalcium Phosphate Based Injectable Synthetic Bone Graft Materials
(Fen Bilimleri Enstitüsü, 2018)As the global population ages, the number of patients suffering from bone tissue loss due to trauma, degenerative diseases, or surgical intervention increases. To meet the demand for bone graft materials, synthetic substitutes ... -
Dejeneratif Kıkırdak Hasarlarına Yönelik Enjekte Edilebilir Hidrojel Sistemlerinin Geliştirilmesi ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2018)Cartilage degeneration is a pathology that develops over time, beginning with the softening of the cartilaginous gland and then completely disappearing. It may be due to trauma, as well as diseases such as osteoarthritis, ... -
Sklera Hasarlarının Rekonstruksiyonunda Otojenik, Allojenik Ve Zenojenik Greftlerin Karşılaştırılması: Yeni Bir Otolog Yaklaşım “Trombositten Zengin Fibrin Membran”
(Fen Bilimleri Enstitüsü, 2018)The purpose of the presented thesis was to compare the effects of xenogenic, allogenic and autogenic graft materials on scleral healing in the repair of scleral tissue damage. For this purpose, scleral tissue damage model ... -
Doku Mühendisliğinde Malzemeye Ve Hücresel Özelliklere Ait İmgelerin Görüntü İşleme Teknikleri İle Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2018)Image processing techniques are frequently used to obtain quantitative information from images of various imaging techniques. Image analysis in tissue engineering and cell biology is a time-consuming and specialized process. ... -
Kütle Spektrometrisi Uygulamalarında Fosfopeptitlerin Hassas Tayini İçin Yeni Stratejilerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2018)Most of the proteins may at some time be phosphorylated on serine, threonine or tyrosine aminoacids when they perform a certain function. Phosphoprotein is protein that contain phosphate group in structure. The smaller ... -
Sferoid Yüklü Ecm-Mimetik Peptit Amfifil Hidrojellerle Çip-Üstü-Karaciğer Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2018-06-28)This study was financially supported by Hacettepe University Scientific Research Projects Coordination Unit with a project entitled “Development of the liver-on-chip to be used in determining the toxicity of drugs” (project ... -
Bor İçeren Nano Hidroksiapatit Kompozitlerin Kemik Hücrelerindeki Moleküler Etki Mekanizmasının Araştırılması
(Fen Bilimleri Enstitüsü, 2018)The structure of the bone and the self-renewal capacity are damaged by metabolic diseases and damages. The trace elements and hydroxyapatite crystals in the bone are important in the development of biomaterials to support ... -
Yüzeylerin Titanyum Nanoçubuklar Ve Onların Altın/Gümüş İle Modifiye Formları İle Nanodesenlenmesi Ve Farklı Alanlarda Kullanılabilirliklerinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2018)Nanoscience and nanotechnology transform the material science into a wide range, providing the continuous development of new nanostructured materials. A comprehensive examination of physicochemical phenomena at the nanoscale ... -
Fenilketonüri Tanısı İçin Kağıt-Tabanlı Mikroakışkan Analitik Cihaz Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2018-10)Phenylketonuria (PKU), is a disease caused by the failure of phenylalanine metabolization and resulting accumulation at blood and other body fluids causing brain damage. Despite periodic phenylalanine monitoring is a ... -
Salinomisin ve BnHAp Yüklü Doku İskelelerinin Antikanserojen ve Antibakteriyel Etkinliğinin Araştırılması
(Fen Bilimleri Enstitüsü, 2018)In the scope of the thesis, it is aimed to investigate the synergistic effect of an anticancer drug, salinomycin, loaded poly (lactic-co-glycolic acid) (PLGA 65:35) nanoparticles with the boron doped nanohydroxyapatite ... -
Nefes Figürü Yaklaşımı ile Sentezlenmiş Gözenekli Poliüretan Filmlerin Hazırlanması, Karakterizasyonu ve Biyouyumluluklarının Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2017)Most of the biomaterials used nowadays are inspired by nature, so enhanced through biomimicing. Materials entegrated to biological systems should be provide morphological and chemical properties of them. Having porous ... -
Aljinat-Halloysit Biyokompozitlere Ciprofloxacin Yüklenmesi, Salımı Ve Adsorpsiyonunun İncelenmesi
(Fen Bilimleri Enstitüsü, 2018)In this thesis, biocomposite HLT-ALJ is loaded with ciprofloxacin (CIP) antibiotic by adding halloysite (HLT) and alginate (ALJ) HLT. HLT nanotubes are naturally occurring clay minerals. HLT located between the layers and ... -
Serpınb1 Ve Serpınb2 Proteaz İnhibitörlerinin Bronş Epitel Hücrelerindeki İnflamatuvar Cevaptaki Rolü
(Fen Bilimleri Enstitüsü, 2018)Asthma is a serious health problem affecting nearly 300 million people worldwide. Asthma frequency varies based on countries and even based on regions of same country. For example, Australia and New Zealand have a frequency ... -
Amoksisilin Baskılanmış Yüzey Plazmon Rezonans Nanosensörler
(Fen Bilimleri Enstitüsü, 2018-01-05)Antibiotics are a type of antimicrobial drug used in the treatment and prevention of bacterial infections. They may either kill or inhibit the growth of bacteria. AMOXicillin (AMOX) is also an antibiotic for the treatment ... -
Bone Tissue Engineering With Mesenchymal Stem Cell Seeded Scaffold Assisted Perfusion Bioreactors
(Fen Bilimleri Enstitüsü, 2017)This study was financially supported by Turkish Scientific and Research Council (Tübitak) Project no: 214M100. In the present thesis study, it was aimed to investigate the potential of proliferation and osteogenic ... -
Poliüretan Tabanlı Kemik Yapıştırıcısı Formülasyonları
(Fen Bilimleri Enstitüsü, 2018)Millions of people are in need of bone injury treatment for many reasons such as traffic accidents, daily injuries, sports injuries. For the stabilization of bone fractures in the health field; plastering, external ... -
Tendon Doku Mühendisliği İçin Poli(Gliserol-Sebakat) (Pgs) Tabanlı Elastomerik Matrisler
(Fen Bilimleri Enstitüsü, 2018)Tendon have an important function in transferring force from muscle to bone. Tendon metabolism can change the structural properties according to the applied mechanical forces.. The natural healing mechanism after the ... -
Manyetik Silika Bazlı Borat Afinite Kromatografisi Sorbentlerinin Sentezi Ve Kromatografik Performanslarının İncelenmesi
(Fen Bilimleri Enstitüsü, 2018-06)In this study, β-nicotinamide adenine dinucleotide (β-NAD) was molecularly imprinted onto plain and magnetic silica microspheres in the monodisperse-porous form, by core-shell polymerization method. For this purpose, ... -
KANSER TEDAVİSİNDE KULLANILAN RESVERATROLÜN İLAÇ TAŞIYICI SİSTEM OLARAK KİTOSAN-ALJİNAT KOMPOZİT BİYOJELLERE YÜKLENMESİ VE SALIMININ İNCELENMESİ
(Fen Bilimleri Enstitüsü, 2018-06-07)In this thesis, Ca - Alginate spheres, Alginate - Chitosan hybrid spheres and resveratrol cross - linked chitosan nanoparticles were synthesized. By using chitosan and alginate biopolymers, biocomposite spheres were ... -
SURFACE IMPRINTED SILICA PARTICLES FOR CONCANAVALIN A PURIFICATION
(Fen Bilimleri Enstitüsü, 2018-02)ABSTRACT SURFACE IMPRINTED SILICA PARTICLES FOR CONCANAVALIN A PURIFICATION Galiya RAZYM Master of Science, Department of Bioengineering Supervisor: Prof. Dr. Handan Yavuz Alagöz January 2018, 65 pages ...