Browsing Temel Tıp Bilimleri Bölümü Tez Koleksiyonu by Department "Fizyoloji"
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Büyüme Çağındaki Sıçanlarda Oral Kaprilik Asit Uygulamasının Açil Ghrelin ve Büyüme Hormonu Düzeyleri ile Anksiyete Üzerine Etkisi
(Tıp Fakültesi, 2022)Caprylic acid is a medium chain fatty acid containing 8 carbons. Caprylic acid is necessary for the conversion of ghrelin which is known as the hunger hormone, to its active form acyl ghrelin. In addition to its functions ... -
Deneysel Parkinson Hastalığı Modelinde Mitokondri Transplantasyonu ve Egzersizin Etkilerinin Karşılaştırılması
(Sağlık Bilimleri Enstitüsü, 2024-10-11)Parkinson's disease (PD) is associated with degeneration of dopamine-secreting neurons in the brain. PD manifests itself with impaired locomotor and spontaneous activities, such as difficulty initiating movement, tremors, ... -
Deneysel Parkinson Hastalığı Modelinde Obezitenin Motor Becerilere Etkisi ve Beyin Tirozin Hidroksilaz Düzeyi, Dopaminerjik Reseptörler ve Leptin Reseptörleri ile İlişkisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023-03)Excessive increase in body weight, which has already become a public health problem, is also associated with many diseases. On the other hand, prolonged life expectancy also increases the incidence of neurodegenerative ... -
Doksorubisin Uygulanan Üçlü Negatif Meme Kanserinde Taurinin Tümör Büyüklüğü ve Metastaz Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2023)Gedikli, E., The Effect of Taurine on Tumor Size and Metastasis in Triple Negative Breast Cancer Treated With Doxorubicin, Hacettepe University Graduate School of Health Sciences Physiology Program PhD Thesis, Ankara, 2023. ... -
Empagliflozinin Sıçanlarda Doksorubisin ile Oluşturulan Kardiyomiyopati Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2021-07-12)Barış V.Ö. Empagliflozin’s Effect on Doxorubicin induced Cardiyomyopathy in Rats Hacettepe University Graduate School of Health Sciences, Doctor of Philosophy Thesis for Physiology, Ankara, 2021 Empagliflozin is an ... -
Farklı Dozlarda ve Sükrozla Birlikte Uygulanan Kakaonun (Theobroma Cacao) Sıçanlar Üzerindeki Anksiyolitik Etkisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023)Anxiety disorder is a common condition. The effectiveness of current pharmacological treatments is delayed and their side effects negatively impact patients. Therefore, patients turn to different products. Cocoa is a ... -
Fokal Serebellar Enfarktlı Fare Hayvan Modelinde Rho-Kinaz İnhibitörlerinin Etkinliği
(Sağlık Bilimleri Enstitüsü, 2018-07-10)According to AHA 2015, stroke is the fifth leading cause of death and is a major cause of serious and long term disability. Cerebellar strokes are account for 3% of all strokes. Early diagnosis and treatment of strokes ... -
Glikoprotein Non-Metastatik Melanoma Protein B (GPNMB), Kan Glukoz Düzeyi ve Karaciğer Yağlanması Arasındaki İlişkinin İncelenmesi
(Tıp Fakültesi, 2023)Although the functions and role of GPNMB, which has been shown to be secreted from the liver and accepted as a hepatokine, and its role in energy balance are not yet known, it is thought to play a role in the ... -
Görme Engelliler İçin Yapay Zeka Destekli Yapay Görme Sistemi
(Tıp Fakültesi, 2021)Artificial intelligence assisted artificial vision system for blind individuals The main purpose of this study is to develop an artificial vision system that has a similar effect to visual perception by using receptive ... -
Hidrojen Peroksite Maruz Kalan Fare Miyoblast Hücre Hattında Oluşan Atrofiye, Melatonin Uygulanmasının Kalpain-1 İfadelenmesine ve Atrofik Morfolojiye Etkisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2018)KARIMISAKHVIDI, N., Investigation of the effect of melatonin administration on calpain-1 expression and atrophic morphology on atrophy of mouse Myoblast cell line exposed to hydrogen peroxide, Hacettepe Graduate School of ... -
Hücre Kültüründe Aromataz/Sirtuin-1 Etkileşiminin miRNA İfade Düzeyine Olan Etkisinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)Kartal, Y. Evaluation of the Relationship Between Aromatase/Sirtuin-1 Interaction and miRNA Expression in Human Neuroblastoma Cells, Hacettepe University Graduate School of Health Sciences Physiology Programme Doctor of ... -
Kadmiyuma Maruz Kalan Sıçanlarda Davranışsal, Biyokimyasal ve Metabolomik Parametrelerde Gözlenen Değişikliklere Karvakrolün Etkisi
(Sağlık Bilimleri Enstitüsü, 24-05-22)Cadmium (Cd) is one of the toxic and carcinogenic heavy metals that can be found in the environment through activities such as industry and agriculture. Carvacrol (CAR) is a phenol found in various aromatic plants. CAR is ... -
Kafein Ve Glikoz Tüketiminin Prefrontal Korteks Aktivitesi ve Bilişsel Performans Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2024-02-05)Caffeine is a psychoactive drug used to improve cognitive functions and is found in coffee, chocolate, various drinks and many medical treatments. Glucose is the most common dietary sugar in mammalian metabolism. Caffeine ... -
L-arjinin ve Agmatinin İnsan NCI-H716 Hücrelerinde GLP-1 ve PYY Salgısı Üzerine Etkisi: Kalsiyum Algılayan Reseptörlerin Rolü
(Sağlık Bilimleri Enstitüsü, 2023-08-14)Agmatine is a natural polyamine produced from L-arginine by arginine decarboxylase and is abundant in foods. One of the most significant effects of glucagon like peptide-1 (GLP1) and peptide YY (PYY) hormones released ... -
Optical Monitoring of Cerebral Blood Flow and Metabolism During Carotid Endarterectomy
(Sağlık Bilimleri Enstitüsü, 2023)Carotid endarterectomy (CEA) is a surgical operation to eliminate plaque in the carotid bifurcation where patients are at risk of embolic stroke. CEA requires crossclamping of carotid arteries (common, internal, and external) ... -
Paklitaksel/Usnik Asit Kombinasyonunun Meme Kanseri Hücre Hatları Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2017)Breast Cancer was the second common cancer worldwide in 2012. Using combination of multiple drugs for treatment has been proven to be more affective by research. Paclitaxel is a chemotherapy medication used to treat a ... -
Parkinson Hastalığı Sıçan Modelinde Motor Aktivite ve İnflamatuvar Sürecin Epigallokateşin Gallat ile Modülasyonu
(Sağlık Bilimleri Enstitüsü, 2023)Parkinson's disease (PD) is a common degenerative disease of the central nervous system. As, there is no cure for the disease currently, and the drugs used for symptomatic improvement neither prevent the progression of ... -
Propriyosepsiyon ve Denge Kontrolü ile El İkinci ve Dördüncü Parmakların Uzunluk Oranı Arasındaki İlişkinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023-07-03)Prenatal exposure to testosterone is known to play an important role in the development of the fetal nervous system, genitourinary system and finger length. Specifically, prenatal testosterone exposure leads to an increase ... -
Salvıa Heldreıchıana’nın (Ayaklı Şalba Ada Çayı) Tek ve Tekrarlayan Dozda Sıçanlar Üzerindeki Anksiyolitik Etkisi
(Tıp Fakültesi, 2023)There is a need for treatment options with a rapid onset of action and fewer side effects that can be used in the acute treatment of anxiety disorders. To meet this need, the anxiolytic-like effect of Salvia heldreichiana, ... -
Santral Puberte Prekoks Tanısı İle İzlenen Kız Çocuklarında Serum Obestatin ve Ghrelin Düzeylerinin İncelenmesi
(Tıp Fakültesi, 2022)It has been observed in recent years that the age of onset of puberty has shifted earlier, particularly in girls. Although obesity is regarded as one of the factors contributing to this situation, the link between prepubertal ...