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    • 1-FENİL-2-(1H-İMİDAZOL-1-İL)ETANON OKSİM ESTERLERİNİN SENTEZİ VE BİYOLOJİK ETKİLERİ ÜZERİNDE ÇALIŞMALAR 

      YURTOĞLU, SİBEL (Sağlık Bilimleri Enstitüsü, 2020-02-19)
      Yurtoglu, S., Studies on Synthesis and Biological Effects of 1-Phenyl-2-(1H-imidazol-1-yl) ethanone oxime esters , Hacettepe University, Institute of Health Sciences, MS Thesis in Pharmaceutical Chemistry, Ankara, 2020. ...

    • 18O-Assisted Dynamic Metabolomics for Individualized Diagnostics and Treatment of Human Diseases 

      Nemutlu, Emirhan; Zhang, Song; Juranic, Nenad O.; Terzic, Andre; Macura, Slobodan; Dzeja, Petras (2012)
      Technological innovations and translation of basic discoveries to clinical practice drive advances in medicine. Today's innovative technologies enable comprehensive screening of the genome, transcriptome, proteome, and ...

    • 18Th European Symposium On Radiopharmacy And Radiopharmaceuticals 

      Radchenko, V.; Engle, J. W.; Roy, C.; Griswold, J.; Nortier, M. F.; Birnbaum, E. R.; Brugh, M.; Mirzadeh, S.; John, K. D.; Fassbender, M. E.; Zhai, Chuangyan; Franssen, Gerben M.; Petrik, Milos; Laverman, Peter; Decristoforo, Clemens; Samia, Ait-Mohand; Véronique, Dumulon-Perreault; Brigitte, Guérin; Summer, D.; Kroess, A.; Rangger, C.; Haas, H.; Laverman, P.; Gerben, F.; von Guggenberg, E.; Decristoforo, C.; Bolzati, Cristina; Salvarese, Nicola; Refosco, Fiorenzo; Meléndez-Alafort, Laura; Carpanese, Debora; Rosato, Antonio; Saviano, Michele; Del Gatto, Annarita; Comegna, Daniela; Zaccaro, Laura; Billaud, Emilie; Ahamed, Muneer; Cleeren, Frederik; Shahbazali, Elnaz; Noël, Tim; Hessel, Volker; Verbruggen, Alfons; Bormans, Guy; Cleeren, F.; Lecina, J.; Koole, M.; Verbruggen, A.; Bormans, G.; Lugatoa, B.; Stucchia, S.; Turollaa, E. A.; Giulianoa, L.; Toddea, S.; Ferraboschib, P.; Klok, R. P.; Mooijer, M. P. J.; Hendrikse, N. H.; Windhorst, A. D.; Collet, C.; Petry, N.; Chrétien, F.; Karcher, G.; Pellegrini-Moïse, N.; Lamandé-Langle, S.; Pfaff, Sarah; Philippe, Cecile; Mitterhauser, Markus; Hacker, Marcus; Wadsak, Wolfgang; Guérard, François; Lee, Yong-Sok; Gouard, Sébastien; Baidoo, Kwamena; Alliot, Cyrille; Chérel, Michel; Brechbiel, Martin W.; Gestin, Jean-François; Lam, K.; Chan, C.; Reilly, R. M.; Paillas, Salomé; Marshall, John; Pouget, Jean-Pierre; Sosabowski, Jane; Briard, Emmanuelle; Auberson, Yves P.; Reilly, John; Healy, Mark; Sykes, David; Paulus, Andreas; Lichtenbelt, Wouter van Marken; Mottaghy, Felix; Bauwens, Matthias; Baranski, Ann-Christin; Schäfer, Martin; Bauder-Wüst, Ulrike; Haberkorn, Uwe; Eder, Matthias; Kopka, Klaus; Chaussard, M.; Hosten, B.; Vignal, N.; Tsoupko-Sitnikov, V.; Hernio, N.; Hontonnou, F.; Merlet, P.; Poyet, J. L.; Sarda-Mantel, L.; Rizzo-Padoin, N.; Cardinale, J.; Schäfer, M.; Benešová, M.; Bauder-Wüst, U.; Seibert, O.; Giesel, F.; Haberkorn, U.; Eder, M.; Kopka, K.; Nematallah, Mansour; Michel, Paquette; Samia, Ait-Mohand; Véronique, Dumulon-Perreault; Roger, Lecomte; Brigitte, Guérin; Fernandez-Maza, L.; Rivera-Marrero, S.; Capote, A. Prats; Parrado-Gallego, A.; Fernandez-Gomez, I.; Balcerzyk, M.; Sablon-Carrazana, M.; Perera-Pintado, A.; Merceron-Martinez, D.; Acosta-Medina, E.; Rodriguez-Tanty, C.; Attili, Bala; Ahamed, Muneer; Bormans, Guy; Philippe, C.; Zeilinger, M.; Scherer, T.; Fürnsinn, C.; Dumanic, M.; Wadsak, W.; Hacker, M.; Mitterhauser, M.; Janssen, B.; Vugts, D. J.; Molenaar, G.T. T.; Funke, U.; Kruijer, P. S.; Dollé, F.; Bormans, G.; Lammertsma, A. A.; Windhorst, A. D.; Vermeulen, Koen; Ahamed, Muneer; Schnekenburger, Michael; Froeyen, Mathy; Olberg, Dag Erlend; Diederich, Marc; Bormansa, Guy; Raaphorst, R. M.; Luurtsema, G.; Lammertsma, A. A.; Elsinga, P. H.; Windhorst, A D.; Rotteveel, Lonneke; Funke, Uta; ten Dijke, Peter; Bogaard, Harm Jan; Lammertsma, Adriaan A.; Windhorst, Albert D.; Song, Lei; Able, Sarah; Falzone, Nadia; Kersemans, Veerle; Vallis, Katherine; Carta, Davide; Salvarese, Nicola; Sihver, Wiebke; Gao, Feng; Pietzsch, Hans Jürgen; Biondi, Barbara; Ruzza, Paolo; Refosco, Fiorenzo; Bolzati, Cristina; Haubner, Roland; Finkensted, Armin; Stegmair, Armin; Rangger, Christine; Decristoforo, Clemens; Zoller, Heinz; Virgolini, Irene J.; Pooters, Ivo; Lotz, Maartje; Wierts, Roel; Mottaghy, Felix; Bauwens, Matthias; Forsback, Sarita; Jörgen, Bergman; Riikka, Kivelä; Karageorgou, M.; Radović, M.; Tsoukalas, C.; Antic, B.; Gazouli, M.; Paravatou-Petsotas, M.; Xanthopouls, S.; Calamiotou, M.; Stamopoulos, D.; Vranješ-Durić, S.; Bouziotis, P.; Lunev, A. S.; Larenkov, A. A.; Petrosova, K. A.; Klementyeva, O. E.; Kodina, G. E.; Kvernenes, O. H.; Adamsen, T. C. H.; Martin, René; Weidlich, Sebastian; Zerges, Anna-Maria; Gameiro, Cristiana; Lazarova, Neva; Müllera, Marco; Luurtsema, Gert; de Vries, Michèl; Ghyoot, Michel; van der Woude, Gina; Zijlma, Rolf; Dierckx, Rudi; Boersma, Hendrikus H.; Elsinga, Philip H.; Lambrecht, Fatma Yurt; Er, Ozge; Ince, Mine; Avci, Cıgır Biray; Gunduz, Cumhur; Sarı, Fatma Aslihan; Ocakoglu, Kasim; Er, Ozge; Ersoz, Onur Alp; Lambrecht, Fatma Yurt; Ince, Mine; Kayabasi, Cagla; Gunduz, Cumhur; Kniess, Torsten; Meister, Sebastian; Fischer, Steffen; Steinbach, Jörg; Ashfaq, Rabia; Iqbal, Saeed; ullah Khan, Irfan; Iglesias-Jerez, R.; Martín-Banderas, L.; Perera-Pintado, A.; Borrego-Dorado, I.; Farinha-Antunes, Ines; Kwizera, Chantal; Lacivita, Enza; Lucente, Ermelinda; Niso, Mauro; De Giorgio, Paola; Perrone, Roberto; Colabufo, Nicola A.; Elsinga, Philip H.; Leopoldo, Marcello; Vaulina, V. V.; Fedorova, O. S.; Orlovskaja, V. V.; Chen, ?�. L.; Li, G. Y.; Meng, F. C.; Liu, R. S.; Wang, H. E.; Krasikova, R. N.; Meléndez-Alafort, Laura; Abozeid, Mohamed; Ferro-Flores, Guillermina; Negri, Anna; Bello, Michele; Uzunov, Nikolay; Paiusco, Martha; Esposito, Juan; Rosato, Antonio; Meléndez-Alafort, Laura; Bolzati, Cristina; Ferro-Flores, Guillermina; Salvarese, Nicola; Carpanese, Debora; Abozeid, Mohamed; Rosato, Antonio; Uzunov, Nikolay; Palmieri, L.; Verbrugghen, T.; Glassner, M.; Hoogenboom, R.; Staelens, S.; Wyffels, L.; Orlovskaja, V. V.; Kuznetsova, O. F.; Fedorova, O. S.; Maleev, V. I.; Belokon, Yu. N.; Geolchanyan, A.; Saghyan, A. S.; Mu, L.; Schibli, R.; Ametamey, S. M.; Krasikova, R. N.; Revunov, Evgeny; Malmquist, Jonas; Johnström, Peter; Van Valkenburgh, Juno; Steele, Dalton; Halldin, Christer; Schou, Magnus; Osati, Samira; Paquette, Michel; Beaudoin, Simon; Ali, Hasrat; Guerin, Brigitte; Leyton, Jeffrey V.; van Lier, Johan E.; Di Iorio, V; Iori, M.; Donati, C.; Lanzetta, V.; Capponi, P. C.; Rubagotti, S.; Dreger, T.; Kunkel, F.; Asti, M.; Zhai, Chuangyan; Rangger, Christine; Summer, Dominik; Haas, Hubertus; Decristoforo, Clemens; Kijprayoon, Suphansa; Ruangma, Ananya; Ngokpol, Suthatip; Tuamputsha, Samart; Filp, Ulrike; Pees, Anna; Taddei, Carlotta; Pekošak, Aleksandra; Gee, Antony D.; Poot, Alex J.; Windhorst, Albert D.; Gunay, Mine Silindir; Ozer, A. Yekta; Erdogan, Suna; Baysal, Ipek; Guilloteau, Denis; Chalon, Sylvie; Galli, Filippo; Artico, Marco; Taurone, Samanta; Bianchi, Enrica; Weintraub, Bruce D.; Skudlinski, Mariusz; Signore, Alberto; Lepareur, Nicolas; Noiret, Nicolas; Hindré, François; Lacœuille, Franck; Benoist, Eric; Garin, Etienne; Trejo-Ballado, F.; Zamora-Romo, E.; Manrique-Arias, J. C.; Gama-Romero, H M; Contreras-Castañon, G.; Tecuapetla-Chantes, R. G.; Avila-Rodriguez, M. A.; Kvaternik, H.; Hausberger, D.; Zink, C.; Rumpf, B.; Aigner, R. M.; Kvaternik, H.; Hausberger, D.; Rumpf, B.; Aigner, R. M.; Janković, Drina; Lakić, Mladen; Savić, Aleksandar; Ristić, Slavica; Nikolić, Nadežda; Vukadinović, Aleksandar; Sabo, Tibor J.; Vranješ-Đurić, Sanja; Vranješ-Đurić, S.; Radović, M.; Janković, D.; Nikolić, N.; Goya, G. F.; Calatayud, P.; Spasojević, V.; Antić, B.; Goblet, David; Gameiro, Cristiana; Lazarova, Neva; Gameiro, Cristiana; Oxley, Ian; Abrunhosa, Antero; Kramer, Vasko; Vosjan, Maria; Spaans, Arnold; Vats, Kusum; Satpati, Drishty; Sarma, Haladhar D.; Banerjee, Sharmila; Wojdowska, W.; Pawlak, D. W.; Parus, L. J.; Garnuszek, P.; Mikołajczak, R.; Pijarowska-Kruszyna, J.; Jaron, A.; Kachniarz, A.; Malkowski, B.; Garnuszek, P.; Mikolajczak, R.; Ilem-Ozdemir, Derya; Caglayan-Orumlu, Oya; Asikoglu, Makbule; Ilem-Ozdemir, Derya; Caglayan-Orumlu, Oya; Asikoglu, Makbule; Eveliina, Arponen; Semi, Helin; Timo, Saarinen; Simo, Vauhkala; Esa, Kokkomäki; Pertti, Lehikoinen; De Simone, Mariarosaria; Pascali, Giancarlo; Carzoli, Ludovica; Quaglierini, Mauro; Telleschi, Mauro; Salvadori, Piero A.; Lam, Phoebe; Aistleitner, Martina; Eichinger, Reinhard; Artner, Christoph; Nakka, Surendra; MC, Hemantha Kumara; Al-Qahtani, Mohammed; Al-Qahtani, Mohammed; Al-Malki, Yousif; Mambilima, N.; Rubow, S. M.; Berroterán-Infante, N.; Hacker, M.; Mitterhauser, M.; Wadsak, W.; Funke, Uta; Cleeren, Frederik; Lecina, Joan; Gallardo, Rodrigo; Verbruggen, Alfons M.; Bormans, Guy; Ramos-Membrive, Rocío; Brotons, Ana; Quincoces, Gemma; Inchaurraga, Laura; de Redín, Inés Luis; Morán, Verónica; García-García, Berta; Irache, Juan Manuel; Peñuelas, Iván; Trabelsi, M.; Cooper, M. S.; Abella, Alejandra; Fuente, Teodomiro; Montellano, Antonio Jesús; Martínez, Teresa; Rabadan, Ruben; Meseguer-Olmo, Luis; Lehtiniemi, P.; Yim, C.; Mikkola, K.; Nuutila, P.; Solin, O.; von Guggenberg, E.; Rangger, C.; Mair, C.; Balogh, L.; Pöstényi, Z.; Pawlak, D.; Mikołajczak, R.; Socan, A.; Peitl, P. Kolenc; Krošelj, M.; Rangger, C.; Decristoforo, C.; Collet, C.; Remy, S.; Didier, R.; Vergote, T.; Karcher, G.; Véran, N.; Pawlak, D.; Maurin, M.; Garnuszek, P.; Karczmarczyk, U.; Mikołajczak, R.; Fredericia, Pil; Severin, Gregory; Groesser, Torsten; Köster, Ulli; Jensen, Mikael; Leonte, R.; Puicea, F. D.; Raicu, A.; Min, E. A.; Serban, R.; Manda, G.; Niculae, D.; Zerna, Marion; Schieferstein, Hanno; Müller, Andre; Berndt, Mathias; Yim, Cheng-Bin; Mikkola, Kirsi; Nuutila, Pirjo; Solin, Olof; Seifert, D.; Ráliš, J.; Lebeda, O.; Selivanova, Svetlana V.; Senta, Helena; Lavallée, Éric; Caouette, Lyne; Turcotte, Éric; Lecomte, Roger; Kochovska, Marina Zdraveska; Ivanovska, Emilija Janjevik; Jokic, Vesna Spasic; Ackova, Darinka Gjorgieva; Smilkov, Katarina; Makreski, Petre; Stafilov, Trajče; Janevik-Ivanovska, Emilija; Alemu, Aschalew; Muchira, Joel Munene; Wanjeh, David Mwanza; Janevik-Ivanovska, Emilija; Janevik-Ivanovska, Emilija; Zdravev, Zoran; Bhonsle, Uday; Alberto, Osso Júnior João; Duatti, Adriano; Angelovska, Bistra; Stojanovska, Zdenka; Sarafinovska, Zorica Arsova; Bosnakovski, Darko; Gorgieva-Ackova, Darinka; Smilkov, Katarina; Drakalska, Elena; Venkatesh, Meera; Gulaboski, Rubin; Colin, Didier J.; Inkster, James A. H.; Germain, Stéphane; Seimbille, Yann (2016)
      OP03 Selective extraction of medically-related radionuclides from proton-irradiated thorium targets, V. Radchenko, J.W. Engle, C. Roy, J. Griswold, M.F. Nortier, E.R. Birnbaum, M. Brugh, S. Mirzadeh, K. D. John, M.E. ...

    • 2,2,7,7-Tetra­Methyl-1,2,3,4,5,6,7,8-Octa­Hydro­Acridine-1,8-Dione 

      Öztürk Yildirim, Sema; Butcher, Ray J.; Şimsek, Rahime; El-Khouly, Ahmed; Şafak, Cihat (2012)
      The whole molecule of the title compound, C17H21NO2, is generated by twofold rotational symmetry. The N atom and the C and H atoms in position 4 of the pyridine ring lie on the twofold axis. The cyclohexene ring has a sofa ...

    • 2-(Imidazol-1-Yl)-1-(2-Naphthyl)Ethanone Oxime 

      Kendi, E; Özbey, S; Karakurt, A; Dalkara, S. (1998)

    • 2-Pirazolin Yapisindaki Yeni Bir Bileşiğin Sentezi, Moleküler Modellemesi Ve Monoaminoksidaz Inhibitörü Etkisinin Araştirilmasi 

      Evranos-Aksöz, B; Uçar, G; Yelekçi, K. (2018)

    • 3,3,6,6-Tetra­Methyl-9-(1-Methyl-1H-Indol-2-Yl)-1,2,3,4,5,6,7,8,9,10-Deca­Hydro­Acridine-1,8-Dione 

      Öztürk Yildirim, Sema; Butcher, Ray J.; El-Khouly, Ahmed; Safak, Cihat; Şimsek, Rahime (2012)
      In the acridine system of the title mol­ecule, C26H30N2O2, both cyclo­hex-2-enone rings adopt sofa conformations. The indole ring system is essentially planar, with a maximum deviation of 0.017 (2) Å for a bridgehead C ...

    • 3,7-Dimethylguanine, A New Purine From A Philippine Sponge Zyzzya Fuliginosa 

      Taşdemir, Deniz; Mangalindan, Gina C; Concepcion, Gisela P; Harper, Mary Kay; Irelanda, Chris M (Pharmaceutical Soc Japan, 2001)
      A new purine 3,7-dimethylguanine (1) has been isolated from the marine sponge Zyzzya fuliginosa, along with the known metabolites. makaluvamines A, C, K (2-4), 4-hydroxyphenylacetic acid (5), methyl ester of 4-hydroxyphenylacetic ...

    • (5-Chloro-1,3-Benzoxazol-2-Ylthio)Acetonitrile 

      ERGIN, O; SILLANPAA, R; SAFAK, C; CALIS, I (Munksgaard Int Publ Ltd, 1994)
      (5-Chloro-1,3-benzoxazol-2-ylthio)acetonitrile, C9H5-ClN2OS, was obtained by the reaction of chloro-acetonitrile with 5-chloro-2-mercaptobenzoxazole. The structure of the title compound was indicated by IR, H-1 NMR and ...

    • 5-Sübstitüe-2-metilbenzensülfonamit Türevlerinin Sentezi ve Farmakolojik Aktivite Çalışmaları 

      Zengin, Merve (Sağlık Bilimleri Enstitüsü, 2024)
      The discovery of dual-target compounds aimed at two different molecular mechanisms has become a popular approach in anticancer drug development studies. In this regard, carbonic anhydrase IX enzyme and vascular endothelial ...

    • 9-(5-Bromo-1H-Indol-3-yl)-1,2,3,4,5,6,7,8,9,10-Deca­hydro­acridine-1,8-Dione Dimethyl Sulfoxide Monosolvate 

      El-Khouly, Ahmed; Öztürk Yildirim, Sema; Butcher, Ray J.; Şimsek, Rahime; Şafak, Cihat (2012)
      In the title compound, C21H19BrN2O2·C2H6OS, the indole ring system is essentially planar, with a maximum deviation of 0.050 (3) Å for the non-bridgehead C atom adjacent to the N atom. The two cyclo­hex-2-enone rings adopt ...

    • A Comparison of Hair and Serum Trace Elements in Patients with Alzheimer Disease and Healthy Participants 

      Koc, Emine Rabia; Ilhan, Atilla; Ayturk, Zubeyde; Acar, Burcu; Gurler, Mukaddes; Altuntas, Aynur; Karapirli, Mustafa; Bodur, Abdurrahman Said (Tubitak Scientific & Technical Research Council Turkey, 2015)
      Background/aim: To determine whether there was a difference between serum and hair trace elements' concentrations in patients with Alzheimer disease (AD) and healthy participants. Materials and methods: Hair and serum ...

    • A Method to Determination of Lead Ions In Aqueous Samples: Ultrasound-Assisted Dispersive Liquid-Liquid Microextraction Method Based on Solidification of Floating Organic Drop and Back-Extraction Followed By Faas 

      Arpa, Çiğdem; Aridaşir, Itır (2018)
      Ultrasound-assisted dispersive liquid-liquid microextraction method based on solidification of floating organic drop and back-extraction (UA-DLLME-SFO-BE) technique was proposed for preconcentration of lead ions. In this ...

    • A New Flavonol Glycoside from the Aerial Parts of Astragalus Vulneraria 

      Bedir, Erdal; Calıs, İhsan; Piacente, Sonia; Pizza, Cosima; Khan, I.A. (2000)

    • A New Generation Of Dihydropyridine Calcium Channel Blockers: Photostabilization Of Liquid Formulations Using Nonionic Surfactants 

      Ioele, Giuseppina; Gündüz, Miyase Gözde; Spatari, Claudia; De Luca, Michele; Grande, Fedora; Ragno, Gaetano (2019)
      The stability profile of a new 1,4-dihydropyridine derivative (DHP), representative of a series with a hexahydroquinoline ring, was studied to design light-stable liquid formulations. This molecule, named M3, has been shown ...

    • A New Perspective On Evaluation Of Medicinal Plant Biological Activities: The Correlation Between Phytomics And Matrix Metalloproteinases Activities Of Some Medicinal Plants 

      Gonulalan, Ekrem-Murat; Nemutlu, Emirhan; Demirezer, Lutfiye-Omur (2019)
      Phytomics or metabolomics is analysis of large-scale primary and secondary metabolites of plant extracts and provides very meaningful data to monitor or evaluate cellular function or systems biology. The activity of plant ...

    • A New Phenylethanoid Glycoside From Phlomis Pungens Willd. Var. Pungens 

      Saraçoğlu, I; Kojima, K; Sebnem Harput, U; Ogihara, Y. (1998)

    • A New Species of Acantholimon Boiss. (Plumbaginaceae) from Ankara, Turkey 

      Dogan, M; Akaydin, G (Wiley-Blackwell, 2002)
      Acantholimon anatolicum Dogan & Akaydin sp. nov. (Plumbaginaceae) is described and illustrated. The species grows on deep gypsum-rich sandy soil on eroded mountain slopes between Cayirhan and Nallihan in Ankara. Diagnostic ...

    • A Novel Alternative for the Treatment of Diabetic Foot Wounds: A Three Dimensional Porous Dermal Matrix 

      Gokce, E.H; Tanriverdi, S.T; Eroglu, I; Tsapis, N; Gokce, G; Fattal, E; Ozer, O. (2017)

    • A Quadruped Study on Chitosan Microspheres Containing Atorvastatin Calcium: Preparation, Characterization, Quantification And In-Vivo Application 

      Eroglu, Hakan; Nemutlu, Emirhan; Turkoglu, Omer Faruk; Nacar, Osman; Bodur, Ebru; Sargon, Mustafa Fevzi; Beskonakli, Etem; Oner, Levent (Pharmaceutical Soc Japan, 2010)
      Atorvastatin is commonly used as a cholesterol lowering agent in patients. Recently, the neuroprotective effects of atorvastatin became the focus of many research studies. In this study, we have formulated chitosan ...