Browsing Eczacılık Fakültesi by Subtype "project"
Now showing items 1-11 of 11
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Akciğer Kanserine Yönelik siRNA Taşıyıcı Polimerik Nanopartiküllerin Geliştirilmesi ve Etkinliklerinin İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022). Lung cancer, one of the most common type of cancers, has the highest mortality rate among all types of cancer, The low effectiveness of current therapies and serious side and toxic effects lead researchers to develop ... -
Akrilamid ve 5-Hidroksimetilfurfural'in Olası Genotoksik Etkilerinin Tek Hücre Jel Elektroforez Yöntemi ile İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)The cooking processes of foods containing carbohydrates forms acrylamide and 5-hydroxymethylfurfural (HMF) as a result of Maillard reaction. According to previous in vivo and in vitro tests, these two substances ... -
Aşılarda Kullanılan Koruyucu ve Adjuvan Maddelerin Olası Toksik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)The World Health Organization defines vaccines as “pharmaceutical products that enable our immune system to recognize and fight pathogens such as viruses and bacteria and protect our body against the diseases caused by ... -
Beyı̇ne Hedeflendı̇rı̇Lmı̇Ş Bevası̇ Zumab YüKlü Nanopartı̇KüLer İLaç TaşIyıcı Sı̇Stemlerı̇N Hazırlanması Ve Etkı̇nlı̇Klerı̇nin Değerlendı̇rı̇Lmesı̇
(Sağlık Bilimleri Enstitüsü, 2020)In this study, in order to target Bevacizumab to the brain, PLGA-PEG nanoparticles conjugated with Anti-CD71 antibodies that bind specifically to transferrin receptors known to be expressed in the blood-brain endothelium ... -
Development of Anticancer Drug Loaded Nanoparticle and In-Vitro Evaluation
(Sağlık Bilimleri Enstitüsü, 2023-03-14)Development of Anticancer Drug Loaded Nanoparticle and In-Vitro Evaluation, Hacettepe University Graduate School of Health Sciences Pharmaceutical Technology Master of Science Thesis, Ankara 2023. Colorectal cancer is the ... -
Erken Adölesan ve Adölesan Dönemde Ftalat Maruziyetinin Epigenetik Mekanizmalar ve Metabolik Profil Üzerindeki Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2021-07-08)Di (2-ethyl hexyl) phthalate (DEHP) is a chemical that has endocrine disrupting properties and is widely used in many customer products. Studies on DEHP show that toxicity specifically targets the male reproductive system. ... -
Gadoterat Meglumin’in Bozunma Ürünlerinin Varlığında Yüksek Basınçlı Sıvı Kromatografisi ile Analizleri
(Sağlık Bilimleri Enstitüsü, 2023)Gadolinium contrast agents are chemicals used in magnetic resonance imaging. When injected into the body, gadolinium contrast agent enhances and improves the quality of magnetic resonance imaging. These substances are ... -
Genisteinin Dna Hasarı Üzerindeki Etkilerinin Kolon Kanseri Hücrelerinde Tek Hücre Jel Elektroforez (Comet) Yöntemiyle Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Çal Doğan, T., Evaluation of The Effects of Genistein on DNA Damage by Single Cell Gel Electrophoresis (Comet) in Colon Cancer Cells, Hacettepe University Institute of Health Sciences Doctor of Philosophy Thesis on ... -
Kuzey Kıbrıs Türk Cumhuriyeti’nde Tüketilen Süt Örneklerinde Aflatoksin M1 Düzeylerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)AFM1 is the hydroxylated metabolite of AFB1, and it is formed in the liver by cytochrome P450 enzymes and can be secreted into the urine, feces and milk of mammals. Since AFM1 is a carcinogenic, cytotoxic, teratogenic, ... -
Potentilla Speciosa Willd. Var. Speciosa Willd. ve Sekonder Metabolitlerinin Α-Glukozidaz ve Tirosinaz İnhibitör Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)Özgünseven, A., Investigation of α-glucosidase and tyrosinase inhibitory effects of Potentilla speciosa Willd. var. speciosa Willd. and its secondary metabolites, Hacettepe University, Graduate School Health Sciences, ... -
The Role and Importance of Dorsal And Ventral Hıppocampal Catecholamınergıc Innervatıons in Socıal Memory of Rats
(Sağlık Bilimleri Enstitüsü, 2022)This study aims to investigate the role and importance of the catecholaminergic innervations in the dorsal (DH) and ventral hippocampus (VH) in social memory of rats. Female Wistar rats were injected bilaterally with ...
