Browsing Eczacılık Fakültesi by Rights "Attribution 4.0 United States"
Now showing items 1-20 of 54
-
A New Generation Of Dihydropyridine Calcium Channel Blockers: Photostabilization Of Liquid Formulations Using Nonionic Surfactants
(2019)The stability profile of a new 1,4-dihydropyridine derivative (DHP), representative of a series with a hexahydroquinoline ring, was studied to design light-stable liquid formulations. This molecule, named M3, has been shown ... -
A New Perspective On Evaluation Of Medicinal Plant Biological Activities: The Correlation Between Phytomics And Matrix Metalloproteinases Activities Of Some Medicinal Plants
(2019)Phytomics or metabolomics is analysis of large-scale primary and secondary metabolites of plant extracts and provides very meaningful data to monitor or evaluate cellular function or systems biology. The activity of plant ... -
Acetylcholinesterase Inhibitory Activities And Lc-Ms Analysis Of The Antioxidant Ferula Caspica M. Bieb. And F. Halophila Pesmen Extracts
(2019)The aim of the current study is to evaluate the biological activity of F. caspica M. Bieb. which is used for the treatment of diabetes in traditional Turkish medicine and to compare with F. halophila Pesmen. Antioxidant ... -
Alpha-Pyrone Glycosides From Scutellaria Salviifolia Benth
(2019)Scutellaria salviifolia Benth. is an endemic species growing in Turkey that belongs to the family Lamiaceae. As a result of a phytochemical study on the aerial parts of S. salviifolia Benth., two new and 10 known compounds ... -
Altered Hdl Particle In Sickle Cell Disease: Decreased Cholesterol Content Is Associated With Hemolysis, Whereas Decreased Apolipoprotein A1 Is Linked To Inflammation
(2019)Background Hypocholesterolemia is the most frequently encountered lipid abnormality in sickle cell disease (SCD). We enrolled pediatric patients to determine the relationships between lipid profile and parameters of ... -
An Exploratory Study Of Neopterin And Kynurenine Pathway In Pterygium
(2019)Pterygium is an inflammatory, vascular and degenerative disorder with unknown aetiology. The aim of this study was to evaluate the changes in neopterin levels, reflecting T-cell immunity, and the kynurenine pathway, the ... -
An In Vitro Study On The Cytotoxicity And Genotoxicity Of Silver Sulfide Quantum Dots Coated With Meso-2,3-Dimercaptosuccinic Acid
(2019)Objectives: Silver sulfide (Ag2S) quantum dots (QDs) are highly promising nanomaterials in bioimaging systems due to their high activities for both imaging and drug/gene delivery. There is insufficient research on the ... -
Analysis Of The Antiproliferative Effect Of Ankaferd Hemostat On Caco-2 Colon Cancer Cells Via Lc/Ms Shotgun Proteomics Approach
(2019)Ankaferd hemostat (ABS), a traditional herbal extract, is a hemostatic agent used for wound healing and bleeding treatment. A standardized form of plants contains many biomolecules. In recent years, previous studies have ... -
Antimicrobial Activity Of Three Scutellaria L. Species From Turkey
(2019)Plant-sourced antimicrobials are known for their therapeutic potency against multi-drug-resistant pathogens. The members of Scutellaria L. have been used to cure several diseases in East Asia, Europe, and North America. ... -
Antioxidants And Selenocompounds Inhibit 3,5-Dimethylaminophenol Toxicity To Human Urothelial Cells
(2019)Exposure to alkyl anilines may lead to bladder cancer, which is the second most frequent cancer of the urogenital tract. 3,5-dimethylaniline is highly used in industry. Studies on its primary' metabolite 3,5-dimethylaminophenol ... -
Bioactivity-Guided Isolation Of Anti-Inflammatory Principles From Cistus Parviflorus Lam.
(2019)Bioactivity-guided fractionation and purification of Cistus parvillorus led to the isolation of two flavan-3-ol derivatives; gallocatechin (1) and epigallocatechin (2) and two flavonoid glycosides; avicularin (3) and ... -
Bmprii Deficiency Impairs Apoptosis Via The Bmprii-Alk1-Bclx-Mediated Pathway In Pulmonary Arterial Hypertension
(2019)Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder characterized by the remodelling of pre-capillary pulmonary arteries. The vascular remodelling observed in PAH patients results from excessive ... -
Capecitabine Induced Hand-Foot Syndrome: A Systematic Review Of Case Reports
(2019)Objective: Capecitabine, a prodrug of 5-fluorouracil, is currently used in the treatment of metastatic colorectal and breast cancers. The aim of this study was to review the pharmacological mechanisms, treatment strategies, ... -
Correction To: Evaluation Of Hydrocar Efficiency For Simultaneous Removal Of Diclofenac And Ibuprofen From Aqueous System Using Surface Response Methodology (Environmental Science And Pollution Research, (2019), 10.1007/S11356-019-04359-Z)
(2019)The original publication of this paper contain typographical mistakes. The published paper had missed letter ‘H’ in some parts of text, references and figure captions. These changes does not affect the findings of paper. ... -
Data The Dehp Induced Changes On The Trace Element And Mineral Levels In The Brain And Testis Tissues Of Rats
(2019)Di (2-ethylhexyl) phthalate (DEHP) is used as plasticizer in the industry and belongs to the phthalate family which can induce tissue damage including kidney, liver, and testis as a result of elevated oxidative stress ... -
Determination Of N-Acetylcysteine In The Presence Of Ciprofloxacin Or Levofloxacin In Microparticulate Dry Powder Inhalers
(2019)A fast and easy method was validated for simultaneous determination of ciprofloxacin hydrochloride mono hydrate (CP), levofloxacin hemihydrate (LV), and N-acetylcysteine (NAC) in samples. The analysis was performed on a ... -
Development Of Dry Powder Inhaler Formulations For Drug Delivery Systems
(2019)Oral or parenteral administration of drugs to treat lung diseases is met with several challenges, including delivery of the active substance in insufficient amounts, inability to produce the desired effect at the target ... -
Direct Enantiomeric Resolution Of Seventeen Racemic 1,4-Dihydropyridine-Based Hexahydroquinoline Derivatives By Hplc
(2019)1,4-Dihydropyridine (DHP) scaffold holds an outstanding position with its versatile pharmacological properties among all heterocyclic compounds. Although most of the commercially available DHPs are marketed as a racemic ... -
Discovery And Characterisation Of Dual Inhibitors Of Tryptophan 2,3-Dioxygenase (Tdo2) And Indoleamine 2,3-Dioxygenase 1 (Ido1) Using Virtual Screening
(2019)Cancers express tryptophan catabolising enzymes indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO2) to produce immunosuppressive tryptophan metabolites that undermine patients’ immune systems, leading ...
