Dosya Biçimi"Yok" Eczacılık Fakültesi için listeleme
Toplam kayıt 69, listelenen: 1-20
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1-FENİL-2-(1H-İMİDAZOL-1-İL)ETANON OKSİM ESTERLERİNİN SENTEZİ VE BİYOLOJİK ETKİLERİ ÜZERİNDE ÇALIŞMALAR
(Sağlık Bilimleri Enstitüsü, 2020-02-19)Yurtoglu, S., Studies on Synthesis and Biological Effects of 1-Phenyl-2-(1H-imidazol-1-yl) ethanone oxime esters , Hacettepe University, Institute of Health Sciences, MS Thesis in Pharmaceutical Chemistry, Ankara, 2020. ... -
Akrilamid ve 5-Hidroksimetilfurfural'in Olası Genotoksik Etkilerinin Tek Hücre Jel Elektroforez Yöntemi ile İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)The cooking processes of foods containing carbohydrates forms acrylamide and 5-hydroxymethylfurfural (HMF) as a result of Maillard reaction. According to previous in vivo and in vitro tests, these two substances ... -
Alkol Esteri Yapısındaki Yeni Azol Türevlerinin Sentezi, Biyolojik Aktiviteleri, Moleküler Modelleme Çalışmaları ve Yapı-Etki İlişkileri
(Sağlık Bilimleri Enstitüsü, 2023)In this study, various carboxylic acid esters of 1-aryl-2-(1H-imidazol-1-yl/1H-1,2,4-triazol-1-yl)ethanol was synthesized in order to discovery new organic compounds with antimicrobial and anticholinesterase effects; ... -
Alkole Bağlı Olmayan Karaciğer Yağlanması Tedavisinde Nano-Enkapsüle İlaçların Etkinliğinin Lc/Q-Tof Ms ile Gerçekleştirilen Metabolomik ve Lipidomik Çalışmalarla İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)In this thesis, the efficacy of vitamin E loaded nanoparticles developed using Human Serum Albumin (ISA) nanoparticles in the treatment of non-alcoholic fatty liver disease (NAFLD) was investigated by LC/Q-TOF MS-based ... -
Antimikobakteriyel Aktivite Göstermesi Beklenen Bazı 2,3-Disübstitüe-5-Metil-4-Tiyazolidinon Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2019-09-07)Ekinci, A. S., Studies on Some 2,3-Disubstituted-5-Methyl-4-Thiazolidinone Derivatives Expected to Show Antimycobacterial Activity, Hacettepe University Graduate School of Health Sciences, MS Thesis in Pharmaceutical ... -
Antineoplastik İlaçların DNA ile Etkileşmelerinin UV-Görünür Bölge Spektroskopisi ile İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2020)Atmaca, L., Investigation of Interactions of Antineoplastic Drugs with DNA by UV-Visible Region Spectroscopy, Hacettepe University Graduate School of Health Sciences Department of Analytical Chemistry Master’s Thesis, ... -
ANTİMİKROBİYAL TEDAVİDE İNTRAVENÖZDEN ORALE GEÇİŞ PROTOKOLÜ GELİŞTİRİLMESİ VE UYGULAMASININ GEÇİŞE ETKİSİ VE KLİNİK ECZACININ ROLÜ
(Sağlık Bilimleri Enstitüsü, 2024)In antimicrobial treatment, it is recommended to switch from intravenous to oral therapy in eligible patients to reduce complications and ensure pharmacoeconomic treatment. In this study, we evaluated the effect of a ... -
Assessment Of Genotoxic Effects Of Pendimethalin In Chinese Hamster Over Cells By The Single Cell Gel Electrophoresis (Comet) Assay
(Turkish Pharmacists Association, 2017)Objectives: Pendimethalin (N-(1-ethylpropyl)-3,4-dimethyl-2,6-dinitrobenzeneamine) is a dinitroaniline herbicide compound which selectively controls weeds. It is a cell division and growth inhibitor. It descends plants in ... -
Azol Halkası Taşıyan COX İnhibitörlerinin Sentezi ve Antimikrobiyal Aktivitelerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2024-01)Nonsteroidal anti-inflammatory drugs (NSAIDs) are the group of drugs that show their effects by inhibiting cyclooxygenase (COX) enzymes and are frequently used in the treatment of pain and inflammation. In addition to these ... -
Bazı 2-Sübstitüe-4-(Furan-2-İlmetil)-6-MetilPiridazin-3(2H)-on Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2021-07-08)In this study, 16 new compounds, 2-[5-(furan-2-ylmethyl)-3-methyl-6-oxopyridazin-1(6H)-yl]-N-(aryl)acetamide (5a-j) and 4-(furan-2-ylmethyl)-6-methyl-2-[2-oxo-2-(4-arylpiperazin-1-yl)ethyl]pyridazin-3(2H)-one (6a-f), which ... -
Benzoksazolinon-hidrazon farmakoforu taşıyan dual etkili mao-aromataz inhibitörlerinin tasarımı ve sentezi: in siliko ve in vitro çalışmalar
(Sağlık Bilimleri Enstitüsü, 2022)Taşçi, N., Design and synthesis of dual MAO-Aromatase inhibitors containing benzoxazolinone-hydrazone pharmacophore: In silico and in vitro studies, Hacettepe University, Graduate School of Health Sciences PhD Thesis in ... -
Betametazon sodyum fosfat ve betametazon dipropiyonat’ın bozunma ürünlerinin varlığında yüksek basınçlı sıvı kromatografisi ile aynı anda analizleri
(Sağlık Bilimleri Enstitüsü, 2023-01)Betamethasone Sodium Phosphate and Betamethasone Dipropionate active ingredients and preservatives were analyzed in the presence of degradation products by HPLC method. -
Böbrek Görüntüleme Amacıyla Kullanılan Teknesyum-99m (Tc-99m) ve Galyum-68 (Ga-68) İşaretli Radyofarmasötiklerin Etkinliklerinin Karşılaştırılması
(Sağlık Bilimleri Enstitüsü, 2022-03-25)PET and SPECT has an obvious diagnostic advantage over anatomical techniques such as classical BT and MR in determining biochemical changes which mainly occurs before anatomical changes. Most powerful sides of PET are ... -
Çocuklar ve ebeveynleri için kullanılacak ‘ilaç tedavisine uyunç’ ve ‘ilaca ilişkin hasta/hasta yakını yaklaşımı’ ölçeklerinin geliştirilmesi ve değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)It is known that the prescription rate of psychotropic drugs in adolescents is increasing, and medication adherence is lower in children and adolescents compared to adults. The effectiveness of psychotropic drugs is very ... -
Development of Anticancer Drug Loaded Nanoparticle and In-Vitro Evaluation
(Sağlık Bilimleri Enstitüsü, 2023-03-14)Development of Anticancer Drug Loaded Nanoparticle and In-Vitro Evaluation, Hacettepe University Graduate School of Health Sciences Pharmaceutical Technology Master of Science Thesis, Ankara 2023. Colorectal cancer is the ... -
Development of Radiopharmaceutical Formulations for Imaging of Non Hodgkin's lymphoma
(Sağlık Bilimleri Enstitüsü, 2022-03-22)Non Hodgkin's Lymphoma (NHL) is the most common subtype of lymphoma, which consists of tumour cells originating from B lymphocyte cells. Burkitt's lymphoma is one of the most common subtypes of NHL, and it is one of the ... -
Dibutil Ftalatın İnsan Akciğer Hücre Hattına Toksik Etkilerinin Değerlendirilmesi ve Askorbik Asit ve N-Asetilsisteinin Olası Koruyucu Etkileri
(Sağlık Bilimleri Enstitüsü, 2020)Endocrine disruptings are chemical substances which are generally produced by humans that disrupt the normal functioning of the body by imitating or blocking hormones. The mostly studied phthalate derivative is ... -
Dihidropiridin Türevlerinin Sentezi ve L-/T-Tipi Kalsiyum Kanal Bloke Edici Aktiviteleri
(Sağlık Bilimleri Enstitüsü, 2022-07-19)1,4- Dihydropyridines (DHPs) are the most well known inhibitors of L-type calcium channels and have important therapeutic value against cardiovascular diseases. Since they target different calcium channel subtypes, they ... -
Dünyada Yeni Aşı Üretiminde Uygulanan Toksikolojik Değerlendirmelerin Karşılaştırılması
(Sağlık Bilimleri Enstitüsü, 2023)Vaccines are complex biological medicinal products containing components such as antigens, adjuvants, and preservatives. They prevent diseasesby stimulating the immune system and providing active immunity. In the last ... -
Dıscovery of New Indoleamıne 2,3-Dıoxygenase 1 (Ido1) Inhıbıtors Through Vırtual Screenıng
(Sağlık Bilimleri Enstitüsü, 2024-01-04)Cancer, a leading global cause of deaths, utilizes mechanisms and pathways to evade the immune system, one of which is the kynurenine (Kyn) pathway, responsible for degrading amino acid L-tryptophan (Trp). Overexpression ...
