Bölüm "Eczacılık Temel Bilimleri" Eczacılık Fakültesi için listeleme
Toplam kayıt 30, listelenen: 1-20
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Activation and Regioselectivity of Five-Membered Cyclic Thionocarbamates to Nucleophilic Attack
(Royal Soc Chemistry, 2013)The cyclic thionocarbamate of alaninol undergoes nucleophilic attack by sulfur nucleophiles at 5-C to give 1-thiopropyl-2-amine derivatives when derivatised on nitrogen with a Boc group. Iodide under microwave conditions ... -
Akut Miyeloblastik Lösemilerde Gen Temelli Kanser Biyobelirteçlerin Tespiti Aracılığıyla İlaç Duyarlılığı Altgruplarının Belirlenmesi ve Prognoz Ve Tedaviye Cevabın Öngörülmesi
(Sağlık Bilimleri Enstitüsü, 2018-12-18)The aim of this study is to determine the gene-based homogeneous subgroups of acute myeloblastic leukemias using the gene expression profiles of renin angiotensin system, the determination of biomarker potentially genes ... -
Antioxidant and Cytotoxic Effects of Moltkia Aurea Boiss
(Acg Publications, 2012)The water extract of M. aurea exhibited strong scavenging effect on 2,2-diphenyl-1-picrylhydrazil (DPPH), nitric oxide (NO) and superoxide (SO) radicals. The free radical scavenging effect of the extract was found comparable ... -
Asetilsalisilik Asidin Amino Asitler Ve Amino Alkollerle Yeni Türevlerinin Sentezi
(Sağlık Bilimleri Enstitüsü, 2018-07-11)Dönmez, B. Synthesis of New Acetylsalicyclic Acid Derivatives Via Amino Acids and Amıno Alcohols, Hacettepe University Health Sciences Institute M.Sci. Thesis in Basic Pharmaceutical Sciences, Ankara, 2018. In this study, ... -
Betametazon sodyum fosfat ve betametazon dipropiyonat’ın bozunma ürünlerinin varlığında yüksek basınçlı sıvı kromatografisi ile aynı anda analizleri
(Sağlık Bilimleri Enstitüsü, 2023-01)Betamethasone Sodium Phosphate and Betamethasone Dipropionate active ingredients and preservatives were analyzed in the presence of degradation products by HPLC method. -
Biyobozunur Poliüretan Bazlı Sert Doku Malzemelerinin Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)It is important to develop hard tissue support products and innovative biomaterials for bone injuries. In this thesis, it is aimed to develop biodegradable polyurethane based bone regenerative films as hard tissue ... -
Cationic Pegylated Polycaprolactone Nanoparticles Carrying Post-Operation Docetaxel For Glioma Treatment
(2017)Background: Brain tumors are the most common tumors among adolescents. Although some chemotherapeutics are known to be effective against brain tumors based on cell culture studies, the same effect is not observed in clinical ... -
Comparison Of Pharmaceutical Pricing And Reimbursement Systems In Turkey And Certain Eu Countries
(2016)Recently, the need for health care services has increased gradually and the limitations in sources allocated for this area have been recognized. Moving from this fact, it has gained a supreme importance to determine what ... -
Dihidropiridin Türevlerinin Sentezi ve L-/T-Tipi Kalsiyum Kanal Bloke Edici Aktiviteleri
(Sağlık Bilimleri Enstitüsü, 2022-07-19)1,4- Dihydropyridines (DHPs) are the most well known inhibitors of L-type calcium channels and have important therapeutic value against cardiovascular diseases. Since they target different calcium channel subtypes, they ... -
Gadoterat Meglumin’in Bozunma Ürünlerinin Varlığında Yüksek Basınçlı Sıvı Kromatografisi ile Analizleri
(Sağlık Bilimleri Enstitüsü, 2023)Gadolinium contrast agents are chemicals used in magnetic resonance imaging. When injected into the body, gadolinium contrast agent enhances and improves the quality of magnetic resonance imaging. These substances are ... -
HepG2, Caco-2 ve HT-29 Kanser Hücrelerinde 2D Jel Elektroforez ve MALDI-TOF/TOF-MS) ile Ankaferd Hemostat’ ın İn-Vitro Antineoplastik Etkisinin Proteomik Açıdan Araştırılması
(Sağlık Bilimleri Enstitüsü, 2019)One of the breakthroughs in life sciences has been accomplished through the completion of the human genome project. However, the compose of the entire genome map has also brought a tough task for scientists. This task is ... -
In Silico Toksikoloji Yöntemleri ve Uygulamaları Üzerine Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2024)The use of computer-assisted toxicology methods (in silico toxicology, computer-based toxicology etc.) in predicting preclinical toxicological endpoints, clinical side effects, and the metabolism of pharmaceutical ... -
Misincorporation Of Free M-Tyrosine Cytotoxic Mechanism For Oxidized A Into Cellular Proteins: A Potential Amino Acids
(Portland Press Ltd, 2006)In vitro studies demonstrate that the hydroxyl radical converts L-phenylalanine into in-tyrosine, an unnatural isomer of L-tyrosine. Quantification of m-tyrosine has been widely used as an index of oxidative damage in ... -
Monitoring The Perturbation Of Soil And Groundwater Microbial Communities Due To Pig Production Activities
(Amer Soc Microbiology, 2013)This study aimed to determine if biotic contaminants originating from pig production farms are disseminated into soil and groundwater microbial communities. A spatial and temporal sampling of soil and groundwater in proximity ... -
Morphologic And Mechanical Characteristics Of Engineered Bovine Arteries
(Mosby-Elsevier, 2001)Objective: The ideal small-caliber arterial graft remains elusive despite several decades of intense research. A novel approach to the development of small-caliber arterial prostheses with a biomimetic system for in vitro ... -
Nonsteroidal Antiinflarmatur İlaçların Toksikolojisi
(Hacettepe Üniversitesi, 2010)Zehirlenmeler yetişkin ve çocuk acil servisleri başta olmak üzere sık karşılaşılan klinik durumlardan biridir. Zehirlenme tedavisinde zamanında ve uygun müdahalenin önemi büyüktür. Zehirlenmeler içerisinde ilaca bağlı ... -
Organik Stereokimya
(Hacettepe Üniversitesi Yayınları, 2014)Stereokimya, farklı bir bilim değil kimya biliminin bir alt alanıdır. Bu alan organik kimya kitaplarında oldukça uygun bir biçimde ayrı bir bölüm olarak bulunmaktadır. Stereokimya, organik kimya içinden doğduğu ve organik ... -
Otomotiv Sanayisi Çalışanlarında Olası Genotoksik Hasarın Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2024-08-31)A lot of people have been employed in the automotive production sector worldwide and our country. Automotive production consists of many steps, at which there are different levels of exposure to welding fumes, paint, ...