Tür "info:eu-repo/semantics/masterThesis" Eczacılık Meslek Bilimleri Bölümü Tez Koleksiyonu için listeleme
Toplam kayıt 78, listelenen: 21-40
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Deneysel Alerjik Astım Modelinde Mitokondri Hedefli Hidrojen Sülfür Donörü AP39 Tedavisinin Etkisinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2023)In this thesis, the effect of AP39, which is a mitochondria targeted slow releasing hydrogen sulfide (H2S) donor, were investigated in a mouse model of ovalbumin (OVA)-induced allergic asthma. In this model, experimental ... -
Dibutil Ftalatın İnsan Akciğer Hücre Hattına Toksik Etkilerinin Değerlendirilmesi ve Askorbik Asit ve N-Asetilsisteinin Olası Koruyucu Etkileri
(Sağlık Bilimleri Enstitüsü, 2020)Endocrine disruptings are chemical substances which are generally produced by humans that disrupt the normal functioning of the body by imitating or blocking hormones. The mostly studied phthalate derivative is ... -
Dihidropiridin Türevlerinin Sentezi ve L-/T-Tipi Kalsiyum Kanal Bloke Edici Aktiviteleri
(Sağlık Bilimleri Enstitüsü, 2022-07-19)1,4- Dihydropyridines (DHPs) are the most well known inhibitors of L-type calcium channels and have important therapeutic value against cardiovascular diseases. Since they target different calcium channel subtypes, they ... -
Eroinin glutatyon metabolizması üzerindeki etkisinin metabolomik düzeyde araştırılması
(Sağlık Bilimleri Enstitüsü, 2023)Heroin is a substance that is a synthetic opioid derivative with a high addictive potential. Serious toxic effects may occur due to heroin use. Although many different mechanisms are effective in the emergence of these ... -
Evaluation of Cytotoxic and Genotoxic Properties of Sinapic Acid
(Sağlık Bilimleri Enstitüsü, 2014)Phenolic compounds, one of the most widely occurring groups of phytochemicals, play an important role in the growth and reproduction of plants, providing protection against pathogens and predators, also contributing towards ... -
Evaluation of Cytotoxicity and Genotoxicity of Eugenol in Lymphocytes
(Sağlık Bilimleri Enstitüsü, 2014)Eugenol is a volatile phenolic constituent of clove essential oil obtained from Eugenia Caryophyllata buds and leaves. It is a functional ingredient in numerous products. It has been used in the pharmaceutical and cosmetics ... -
Febril Nötropeni Gelişim Riski Olan ve Granülosit Koloni Stimüle Edici Faktör (G-Csf) Kullanan Kanser Hastalarının Patıent Rısk Score (Prs) ile Takibi ve Yan Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-06)Febrile neutropenia is the most important dose-limiting side effect of chemotherapy. Although the international treatment guidelines recommend prophylactic use of G-CSF in chemotherapy protocols with a risk of febrile ... -
Gentiana olivieri Griseb.’in Nöroprotektif Etkisi
(Sağlık Bilimleri Enstitüsü, 2024-06-25)The genus Gentiana has 400 species in the world and 12 species in Türkiye, and plants belonging to this genus have had a wide range of uses in folk medicine for many years. Gentiana olivieri Griseb. used in Southeastern ... -
Geriatri Polikliniği Ve Huzurevi Hastalarının STOPP/START ve MAI Kriterleri ile Değerlendirilmesi ve Müdahalelerin Yapılmasında Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2017-07-13)In this thesis, second version of "Screening Tool of Older People’s Potentially Inappropriate Prescriptions (STOPP)” and " Screening Tool to Alert Doctors to Right Treatment (START)” criteria have been used to determine ... -
Hashimoto Tiroiditinde Selenyum ve Selenoprotein Düzeyleri ile Oksidatif Stres Biyogöstergelerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)Hashimoto's thyroiditis (HT) is an autoimmune disease of thyroid gland. In the course of the disease, thyroid gland is attacked by a variety of cell- and antibody-mediated immune processes. It is reported that high iodine ... -
Hepatit B ve C Virüsü ile Enfekte Hastaların Tedavisinde İlaç Kaynaklı Sorunlar
(Sağlık Bilimleri Enstitüsü, 2018)Hepatitis B and C are the leading cause of cirrhosis and hepatocellular carcinoma. A low diagnosis rate and poor access to clinical care are a major risks in hepatitis B and C‐related morbidity and mortality. Lack of ... -
İç Hastalıkları Servislerinde Yatan Hastalarda Uygun Olmayan Endikasyonlarda Oral Proton Pompası İnhibitörleri Kullanımının Tespit Edilmesi ve Hasta Uyuncunun Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2017)The use of unnecessary proton pump inhibitors (PPIs) is very common in the world and in our country also. This situation increases the risk of many adverse reactions and drug interactions. For this reason, in order to ... -
İnme Geçiren Hastalarda Yaşam Kalitesi ve Tedaviye Uyunç Üzerine Klinik Eczacının Katkısı
(Sağlık Bilimleri Enstitüsü, 2019)Stroke is defined as the sudden onset of a focal neurological problem lasting more than 24 hours, is one of the leading causes of repetitive and disability, affecting the quality of life of the patients negatively, causing ... -
İnsan Kolostrum Sütünde Neopterin ve Kinürenin Düzeylerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)Deliveli, S., Examining the amounts of neopterin and kynurenine in human colostrum milk, Hacettepe University Graduate School of Health Sciences, Pharmaceutical Toxicology Program, Master Thesis, Ankara, 2021. Colostrum ... -
İnsan Nöroblastoma Hücre Kültüründe Amiloid Beta ile Oluşturulan Alzheimer Hastalığı Modelinde Atorvastatinin Sestrin-2, Sirtuin-1, TPP1 ve LC3B Ekspresyonuna Etkisi.
(Sağlık Bilimleri Enstitüsü, 2019-02)Çelik, H. The Effect of Atorvastatin on Sestrin-2, Sirtuin-1, TPP1 and LC3B in Amyloid Beta Induced Alzheimer’s Disease Model in Human Neuroblastoma Cell Culture. Hacettepe University Graduate School of Health Sciences, ... -
Kanser Hastalarında Tromboz Riskinin ve Antikoagülan Tedavinin Rehbere Uygunluğunun Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020-01-15)Cancer patients are at high risk for venous thromboembolism (VTE) and cancer-associated VTE is a major health problem due to its effects on deterioration of disease prognosis, increased treatment costs and delayed cancer ... -
Kanser Hastalarının Opioid Analjezik Kullanımına İlişkin Görüşlerinin Değerlendirilmesi ve Hasta Eğitiminde Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2020)Pain is a common syndrome among cancer patients that has a negative impact on the physiological functions, psychological well-being, quality of life of patients, and that also requires a good management. Patients and their ... -
Kojik Asit Türevi Bileşiklerin Tasarımı, Sentezi ve Melanoma Hücresine Karşı Sitotoksisiteleri ile Tirozinaz İnhibisyonu Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)Tyrosinase is an enzyme that acts as a catalyst in the biosynthesis of melanin pigment, which is found in fungi, in plants and in animals. Overproduction and accumulation of this pigment causes hyperpigmentation, post ... -
Kondanse 1,4-Dihidropiridin Türevlerinin Sentezi ile Antimikrobiyal ve Antioksidan Etkileri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2019)BAYDAR, E. The Studies on Synthesis of Condensed 1,4-Dihydropyridine Derivatives and Their Antimicrobial and Antioxidant activities, Hacettepe University, Graduate School of Health Sciences, Master Thesis in Pharmaceutical ... -
Kondanse 1,4-Dihidropiridin Türevlerinin Sentezi ve L-/T-Tipi Kalsiyum Kanalları Üzerine Etkileri
(Sağlık Bilimleri Enstitüsü, 2019)1,4-Dihydropyridines (DHPs) are crucial blockers of different calcium channel subtypes and have great therapeutic value against cardiovascular and neurophysiologic conditions. In this thesis, the design and the synthesis ...