Kanser Enstitüsü: Recent submissions
Now showing items 61-80 of 111
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Cancer Trends and Incidence and Mortality Patterns in Turkey
(Oxford Univ Press, 2011)Cancer incidence and mortality rates have been increasing in Turkey as most of the developing countries. Besides socioeconomic factors, one of the most prominent attributes of developing countries is the dissimilarity of ... -
Cancer Burden In Four Countries Of The Middle East Cancer Consortium (Cyprus; Jordan; Israel; Izmir (Turkey)) With Comparison To The United States Surveillance; Epidemiology And End Results Program
(Elsevier Sci Ltd, 2016)It is important that population-based cancer registries provide accurate and reliable data for public health purposes. These data are essential data for planning of cancer control and prevention. In this study, we examined ... -
Lack of Association Between the Mthfr C677T Polymorphism and Lung Cancer in a Turkish Population
(Asian Pacific Organization Cancer Prevention, 2014)Background: In this case-control study, we aimed to investigate the relationship between the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and lung cancer. Materials and Methods: Total 200 individuals ... -
Lack of Any Relationship Between Abo and Rh Blood Groups and Clinicopathological Features in Patients with Gastrointestinal Stromal Tumors
(Asian Pacific Organization Cancer Prevention, 2012)Background: An association between the ABO blood group and the risk of certain malignancies, including pancreatic and gastric cancer, has been reported previously. However, it is unclear whether this association is valid ... -
Metastatic Medullary Thyroid Cancer: A Dramatic Response To A Systemic Chemotherapy (Temozolomide And Capecitabine) Regimen
(Dovepress, 2015)A 40-year-old male patient presented with increasing serum levels of calcitonin and CEA. He underwent potential curative surgery for medullary thyroid carcinoma, 3 years ago and then 7 months later he had metastasectomy ... -
Effect of Zoledronic Acid on Rats' Tissue Sdf-1 Expression
(Akad Doktorlar Yayınevi, 2016)Zoledronic acid has been shown to inhibit cancer cell proliferation, metastasis and induce cancer cell apoptosis. Stromal Derived Factor-1 (SDF-1) is a chemokine that has been reported to be expressed markedly high in the ... -
Is Plasma Caveolin-1 Level a Prognostic Biomarker in Metastatic Pancreatic Cancer?
(Wolters Kluwer - Medknow, 2017)Background/Aims: To evaluate the prognostic significance of plasma caveolin (CAV)-1 and its association with survival and treatment response rates in metastatic pancreatic cancer (MPC). Patients and Methods: Plasma samples ... -
Aml Hastalarında Nkp30 Ve B7-H6, Gal-3, Bag6 Ekspresyon Düzeyleri İle Nk Hücre Sitotoksitesi Arasındaki İlişki
(Kanser Enstitüsü, 2020-01-10)ABSTRACT Aydın,B. The relationship between NKp30 and B7-H6, Gal-3, BAG6 expression levels and NK cell cytotoxicity in AML patients. Master of Science Thesis of Hacettepe University Graduate School of Health Sciences ... -
Genişletilmiş Bilgisayarlı Tomografi Skalası Ve Metal Artefakt Azalımı Yöntemlerinin İmplantlı Hastalarda Doz Dağılımına Etkisinin Bireyselleştirilmiş Fantomlar Kullanılarak Analiz Edilmesi
(Kanser Enstitüsü, 2019-09)Analysis of The Effects of Extended Computed Tomography Scale and Metal Artefact Reduction Methods on Dose Distribution of Patient with Implant by Using Individualized Fantoms. Hacettepe University Graduated School of ... -
Interactıon Mechanısms Between Small Cell Lung Cancer Cells And T Lymphocytes
(Kanser Enstitüsü, 2019-08)Tumors are capable of reshaping their microenvironment to escape from immune destruction. For this purpose, tumor cells initiate an immune regulatory program that is typically used by the normal cells to mitigate ... -
Evaluation of T Cell Responses In The Co-Cultures Establıshed Wıth Neutrophıls, Monocytes, and Lung Adenocarcınoma Cells
(Kanser Enstitüsü, 2019)CD4+ and CD8+ T cells are critical mediators in anti-tumor immunity. Together with neutrophils, they have been shown to dominate the immune landscape of the non-small cell lung cancer (NSCLC). A number of studies have ... -
Prostat Kanserinde Tlr Agonistlerinin M1, M2 Makrofaj Polarizasyonunda Rolü
(Kanser Enstitüsü, 2019)It is well known that inflammation is effective in the development of prostate cancer. Macrophages in the tumor microenvironment are either anti-inflammatory M2-type that help tumor growth or pro-inflammatory M1-type that ... -
Çinko Katkılanmış Hidroksiapatit Nanoparçacıklarının Kanser Hücrelerinin Radyoduyarlılığına Etkisi
(Sağlık Bilimleri Enstitüsü, 2019-04-09)Yedekçi, F.Y., Effect Of Zinc Doped Hydroxyapatite Nanoparticles On Radiosensitivity Of Cancer Cells, Hacettepe University, Graduate School of Health Sciences, Radiation Therapy Physics, Doctor of Philosophy Thesis, Ankara, ... -
Meme Kanseri Hücreleri Tarafından Üretilen Fibronektinin Miyeloid Hücre Karakteri Üzerine Etkisi
(Kanser Enstitüsü, 2019)Basal-like breast cancer (BLBC) possess high capacity to regulate inflammation and identified with high-level myeloid cell infiltration. Extracellular matrix components produced by tumor cells, e.g. fibronectin (FN), can ... -
Cxcl Kemokı̇n ÖncüL Dı̇zelerı̇nden Türevlenen Küçük Peptı̇t MoleküLlerı̇nin İmmün Düzenleyı̇cı̇ Etkı̇sinin Değerlendirmesı̇
(Kanser Enstitüsü, 2019-03-12)Peptide structured small molecules function in the regulation of a variety of physiological processes and intercellular communication. In this study, precursor sequences of known 17 CXCL chemokine molecules were analyzed ... -
Kolorektal Kanserlerde Th17 İlişkili IL-17, IL-21 ve IL-22 Sitokinlerinin Ekspresyon Düzeylerinin Belirlenmesi
(Sağlık Bilimleri Enstitüsü, 2019)Immune system cells and released cytokines in tumor microenvironment have a very important role in cancer prognosis. Also, T-helper 17 (Th17) cells have been frequently found in many tumors microenvironment and their effects ... -
CyberKnife® Robotik Radyocerrahi Cihazında MAGIC Polimer Jel Dozimetre İle Küçük Alan Dozimetrisinin İncelenmesi
(Kanser Enstitüsü, 2018)ENKAVİ, M.F. Investigation of Small Field Dosimetry with MAGIC Polymer Gel Dosimeter in CyberKnife® Robotic Radiosurgery Device. Hacettepe University Institute of Health Sciences, MSc. Thesis in Radiotherapy Physics Program, ... -
Inhibition of Serum and Glucocortıcoıd Inducible Kinase 1 (Sgk1) in Triple Negative Breast Cancer
(Kanser Enstitüsü, 2018-07-18)Glucocorticoid receptor overexpression leads to poor prognosis in breast cancer, particularly in triple negative phenotype. This poor prognosis has been shown to be due to the activation of SGK1 (serum and glucocorticoid ... -
Meme Kanserinde, Normal Fibroblastlar ve Kanserle İlişkili Fibroblastların Monosit Çağrılması, Makrofaj Polarizasyonu ve İnvazyona Etkisi
(Kanser Enstitüsü, 2018)GÖK YAVUZ B., The Effect of Cancer Associated Fibroblasts and Normal Fibroblasts on Monocyte Recruitment, Macrophage Polarization and Invasion in Breast Cancer. Hacettepe University Institute of Health Sciences Ph.D Thesis ... -
Evaluation of Metadherin Expression in Breast Cancer
(Sağlık Bilimleri Enstitüsü, 2018)Metadherin gene (MTDH/ AEG-1/ Lyric) encodes a 582- aminoacid protein, metadherin (MTDH), which is almost undetectable by immunohistochemistry in normal breast tissue. MTDH expression is markedly increased in breast cancer ...
