Dil "en" Kanser Enstitüsü için listeleme
Toplam kayıt 62, listelenen: 1-20
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3′End Maturation of Human Telomerase Rna Component (Terc) and Its Effects on Telomere Dynamics
(Sağlık Bilimleri Enstitüsü, 2017-09-15)Telomerase RNA Component (TERC) is the non-coding RNA template and scaffold of the telomerase holoenzyme. TERC level has been shown to be a limiting factor for telomerase activity, lower levels resulting in telomere diseases ... -
Akciğer Kanser Hücrelerinden Salınan Eksozomların Makrofaj Polarizasyonuna ve Fonksiyonlarına Etkisinin Araştırılması
(Kanser Enstitüsü, 2021)Lung cancer has the highest mortality rate in both men and women worldwide. With our developing technology and knowledge, the research of methods in cancer targeted treatments have turned to target such as tumor microenvironment, ... -
Cancer Associated Fibroblasts Have Phenotypic and Functional Characteristics Similar To The Fibrocytes That Represent A Novel Mdsc Subset
(Taylor & Francis Inc, 2015)Circulating fibrocytes were reported to represent a novel myeloid-derived suppressor cell (MDSC) subset and they were also proposed to be involved in the tumor immune escape. This novel fibrocyte subset had a surface ... -
Cancer Burden In Four Countries Of The Middle East Cancer Consortium (Cyprus; Jordan; Israel; Izmir (Turkey)) With Comparison To The United States Surveillance; Epidemiology And End Results Program
(Elsevier Sci Ltd, 2016)It is important that population-based cancer registries provide accurate and reliable data for public health purposes. These data are essential data for planning of cancer control and prevention. In this study, we examined ... -
Cancer Trends and Incidence and Mortality Patterns in Turkey
(Oxford Univ Press, 2011)Cancer incidence and mortality rates have been increasing in Turkey as most of the developing countries. Besides socioeconomic factors, one of the most prominent attributes of developing countries is the dissimilarity of ... -
Comparatıve Analysıs of Myeloıd-Derıved Suppressor Cells From Blood and Spleen in Gastrıc and Pancreatıc Cancer
(Sağlık Bilimleri Enstitüsü, 2022-07-29)Under physiological conditions, development and maturation of the myeloid cells take place in the bone marrow. In case of chronic inflammatory disorders such as cancer, production of chemokines, growth factors, and cytokines ... -
Cytoreductive Surgery For Intestinal Cancer Patients Metastatic To Ovaries Presenting As Primary Ovarian Cancer
(Akad Doktorlar Yayınevi, 2016)Colorectal cancer accounts for one third of non-genital tumors metastasize to the ovaries. We aimed to investigate the role of cytoreductive surgery in colon and small intestinal cancer patients with adnexal metastases, ... -
Deep Vein Thrombosis Following Non-Myeloablative Allogeneic Stem Cell Transplantation: Presentation of Three Cases and Literature Review
(Galenos Yayınevi, 2013)The incidence of deep vein thrombosis (DVT) after non-myeloablative (NMA) allogeneic stem cell transplantation (allo-SCT) is unknown. In addition, very few studies on the predisposing factors for DVT post SCT have been ... -
Determinants of New-Onset Atrial Fibrillation in Patients Receiving Crt Mechanistic Insights From Speckle Tracking Imaging
(Elsevier Science Inc, 2016)OBJECTIVES The aim of this study was to investigate the factors associated with the development of atrial fibrillation (AF) and to examine the impact of these factors for long-term outcome after cardiac resynchronization ... -
Effect of Calcıum Carbonate Encapsulatıon on the Oral Actıvıty of Cpg Olıgodeoxynucleotıdes and Assessment of the Response of Human Monocytes to Tlr Lıgands
(Sağlık Bilimleri Enstitüsü, 2018-03)Toll-like receptor (TLR) ligands modulate immune responses and have been used in immunotherapy. Clinical trials designed to evaluate the utility of CpG ODN, a synthetic TLR9 ligand, relied on parenteral routes of administration. ... -
Effect of Zoledronic Acid on Rats' Tissue Sdf-1 Expression
(Akad Doktorlar Yayınevi, 2016)Zoledronic acid has been shown to inhibit cancer cell proliferation, metastasis and induce cancer cell apoptosis. Stromal Derived Factor-1 (SDF-1) is a chemokine that has been reported to be expressed markedly high in the ... -
Efficacy of Adjuvant Aromatase Inhibitor In Hormone Receptor-Positive Postmenopausal Breast Cancer Patients According To The Body Mass Index
(Cancer Research UK, 2012)Background: Increased adiposity may trigger signalling pathways that induce aromatase expression. As aromatase inhibitors exert their effects by blocking the aromatase enzyme, higher body mass index (BMI) can reduce the ... -
Efficacy of Sorafenib In Advanced Differentiated and Medullary Thyroid Cancer: Experience In A Turkish Population
(Dovepress, 2014)Purpose: Chronic otitis media with effusion (OME) is the leading cause of hearing loss during childhood. In bacterial etiology of OME, the most frequent pathogens responsible are Haemophilus influenzae followed by Streptococcus ... -
Evaluation of Metadherin Expression in Breast Cancer
(Sağlık Bilimleri Enstitüsü, 2018)Metadherin gene (MTDH/ AEG-1/ Lyric) encodes a 582- aminoacid protein, metadherin (MTDH), which is almost undetectable by immunohistochemistry in normal breast tissue. MTDH expression is markedly increased in breast cancer ... -
Evaluation of T Cell Responses In The Co-Cultures Establıshed Wıth Neutrophıls, Monocytes, and Lung Adenocarcınoma Cells
(Kanser Enstitüsü, 2019)CD4+ and CD8+ T cells are critical mediators in anti-tumor immunity. Together with neutrophils, they have been shown to dominate the immune landscape of the non-small cell lung cancer (NSCLC). A number of studies have ... -
Expression and Functional Analysis of Ccrl2 Atypical Chemokine Receptor Variants on Breast Cancer Cells
(Kanser Enstitüsü, 2014)The complex network of chemokines and chemokine receptors is regulated by atypical (decoy) chemokine receptors. Atypical chemokine receptors play role in the termination of inflammatory responses and CCRL2 is the newest ... -
Expression of Toll Like Receptors in Lung Cancer and Investigating Their Effect on Apoptosis
(Kanser Enstitüsü, 2014)Members of the Toll like receptors (TLRs) family play key roles in both innate and adoptive immune responses. TLRs proteins enable host to recognize a large number of pathogen associated molecular patterns such as bacterial ... -
Functions of the Activation Induced Cytidine Deaminase (AID) and Toll-like Receptors (TLR) on Regulation of the Central B cell Tolerance Checkpoint
(Sağlık Bilimleri Enstitüsü, 2022-09)Çakan, E., Functions of the Activation Induced Cytidine Deaminase (AID) and Toll-Like Receptors (TLR) on Regulation of the Central B Cell Tolerance Checkpoint, Hacettepe University Graduate School Health Sciences Program ... -
Good Outcomes Of Patients With Stage Ib Endometrial Cancer With Surgery Alone
(Asian Pacific Organization Cancer Prevention, 2014)Background: Most patients with endometrial cancer have stage I disease. Adjuvant therapy in stage IB (formerly IC) endometrial cancer is controversial, treatment options including observation or brachytherapy/radiotherapy ... -
Higher Ki67 Expression Is Associates With Unfavorable Prognostic Factors and Shorter Survival in Breast Cancer
(Asian Pacific Organization Cancer Prevention, 2014)Background: The prognostic value of the Ki67 expression level is yet unclear in breast cancer. The aim of this study was to investigate the association between Ki67 expression levels and prognostic factors such as grade, ...
