Hacettepe Üniversitesi Açık Erişim Sistemi (HÜAES)

  • HÜAES, Hacettepe Üniversitesi bünyesinde üretilen kitap, makale, tez, bildiri, rapor gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, etkisini artırmak için telif haklarına uygun olarak Açık Erişime sunar.
 

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ARGÜMANTASYONA DAYALI SOSYOBİLİMSEL KONU TEMELLİ FEN ÖĞRETİMİNİN ETKİLİLİĞİNE YÖNELİK KARMA YÖNTEM ARAŞTIRMASI
(Eğitim Bilimleri Enstitüsü, 2026) Liman Suna; Matematik ve Fen Bilimleri
The main objective of this research is to examine the effects of argumentation-based socioscientific issue (SSI) based science teaching on middle school students' attitudes towards socioscientific issues, awareness, and critical thinking dispositions. Additionally, how this application affects students' argumentation skills and students' opinions regarding this process have been investigated. The study simultaneously employed an embedded mixed methods design, using a quasi-experimental pretest-posttest control group design and an observational case study. The research group consisted of a total of 103 seventh-grade students studying in Ankara during the 2024-2025 academic year, comprising 53 students in the experimental group and 50 in the control group. Quantitative data were collected using the Attitude towards Socioscientific Issues Scale, the Critical Thinking Disposition Scale, and the Socioscientific Awareness Scale, while qualitative data were obtained through focus group interviews, observation, and document analysis techniques. The quantitative findings of the research determined that the implemented teaching method significantly increased the critical thinking dispositions (p <.05) and attitudes towards socioscientific issues (p = .00) of the students in the experimental group. Although no statistically significant quantitative difference was found in awareness scores (p > .05), qualitative findings revealed that this approach provided a significant improvement in the quality and depth of students' awareness levels. Quantitative findings regarding argumentation competencies showed a significant increase in total scores (p <.01). Statistically significant improvements were observed in the Data, Reasoning, and Supportive components. However, no quantitatively significant improvement was observed in the refutative component, which is defined as the ability to refute opposing claims and is cognitively the most complex. Qualitative findings clearly indicated that students found the process generally fun and enjoyable, liked discussing, and expressed that their interest in and participation in science lessons increased.
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Hacettepe Üniversitesi İç Hastalıkları Yoğun Bakım Ünitesinde İzlenen Hastalarda Kronik Kritik Hastalık Ve Persistan İnflamasyon İmmünsüpresyon Ve Katabolizma Sendromu Prevalansının Araştırılması
(Tıp Fakültesi, 2025-10-14) Şahin Mehmet Ali; Halaçlı Burçin; İç Hastalıkları
Advances in intensive care have increased survival from the acute phase of critical illness. However, this has also led to a large and growing population of chronically ill patients who remain dependent on prolonged mechanical ventilation (MV) and other intensive care therapies, requiring multiple organ support. This condition, termed chronic critical illness (CCI), imposes a substantial burden on health systems (1). There is no universally accepted definition of CCI in the literature. Our study aimed to compare the prevalence and patient characteristics according to four commonly used CCI definitions among patients admitted to the Internal Medicine Intensive Care Unit at Hacettepe University. We also examined the characteristics of patients with Persistent Inflammation, Immunosuppression, and Catabolism Syndrome (PIICS), a subgroup within CCI. Between 10/01/2023 and 03/31/2025, of 1,074 patients admitted to the Internal Medicine ICU, 823 were included after excluding inter-hospital transfers (n=22) and readmissions (n=229). Patients were evaluated according to four previously defined CCI definitions and CCI prevalence rates were determined. The four CCI definitions were as follows: CCI-1: need for MV (≥6 hours/day) for ≥21 days (2); CCI-2: requirement for MV for 14–21 days or longer, or tracheostomy (3); CCI-3: ICU length of stay ≥8 days with at least one of the following: MV (≥96 hours in a single episode), tracheostomy, stroke, head trauma, sepsis, or major trauma (4); CCI-4: ICU stay ≥14 days and, on day 14, cardiovascular SOFA score ≥1 and/or other component scores ≥2 (5). PIICS diagnostic criteria: ICU length of stay ≥14 days; CRP >150 μg/dL; total lymphocyte count <0,80 ×10⁹/L; serum albumin <3,0 g/dL; prealbumin <10 mg/dL; creatinine increase index <80% (6). Of the 823 included patients, 460 (55.89%) were male. The median age was 67 years (IQR 54–77). CCI prevalence was: CCI-1, 5.47% (n=45); CCI-2, 9.36% (n=77); CCI-3, 24.18% (n=199); and CCI-4, 19.68% (n=162). PIICS prevalence was 8.26% (n=68). Among patients meeting CCI-4 criteria, the prevalence of PIICS was 41.97%. In multivariable and machine-learning analyses, the prominent parameters for CCI-3, CCI-4, and PIICS included APACHE II score, SOFA, endotracheal intubation within the first 24 hours, presence of neurological disease, hypoalbuminemia, CRP/procalcitonin, BUN/creatinine, PaCO₂, and elevated lactate. This study is the first to prospectively compare CCI definitions and prevalence and to evaluate PIICS prevalence in a medical ICU. The finding that different definitions yield different prevalence rates highlights the need for an ideal, easily applicable definition of CCI and underscores the necessity for further research focusing on PIICS.
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Kronik hava yolu hastalıklarında spirometrik ölçütlerin değerlendirilmesi
(Tıp Fakültesi, 2023) Maide Gözde İnam; Göğüs Hastalıkları
Spirometry is the most commonly used repeatable pulmonary function test in the diagnosis and monitoring of lung diseases. Forced expiratory volume in the first second (FEV1), forced vital capacity (FVC) and FEV1 / FVC ratio are parameters that can be measured by spirometry and provide information about airway diseases. International guidelines have published standardization criteria for evaluating spirometric parameters. However, the test performed is dependent on the patient's effort and requires the patient's compliance while performing the test. The aim of this study is to develop physiological parameters related to airway diseases using spirometry measurements and to compare these parameters with existing spirometric parameters. In our study, the data of 12,326 spirometry tests were analyzed using mathematical modeling and newly defined parameters were examined with ROC curves. In the model, the area under the curve (AUC) was found to be 0.988 (95% confidence interval (CI) 0.986-0.990), (sensitivity (Se) 95% and specificity (Sp) 95%) for t2; 0.986 (95% CI 0.984-0.988) (Se 97%, Sp 92%) for t3; 0.929 (95% CI 0.922-0.935) (Se 88%, Sp 84%) for t4; 0.881 (95% CI 0.872-0.890) (Se 78%, Sp 82%) for t1 geometric mean (gmean); 0.849 (95% CI 0.839-0.859) (Se 75%, Sp 79%) for tp gmean; 0.912 (95% CI 0.905-0.919) (Se 85%, Sp 82%) for tq gmean (p<0.001 for all measurements). The t2 and t3 parameters were found to be more specific and sensitive than the maximal mid-expiratory flow (MMEF25-75%) value in detecting airway obstruction. Our research has shown that these parameters have a strong relationship with airway obstruction.
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Ebeveynlerin Çocuk ihmal ve İstismarına Yönelik Farkındalık ve Biliş Düzeylerinin Değerlendirilmesi: Ordu İli Örneği
(Sosyal Bilimler Enstitüsü, 2026-01) Bulut Uçar Cansu; Sosyal Hizmet
The aim of this study is to examine the awareness and cognitive levels of parents with preschool children regarding child abuse and neglect in terms of various sociodemographic variables. The research was conducted using the relational survey model to determine the relationships among variables. The study was carried out on a sample consisting of parents with preschool children living in Ordu Province.The study group consisted of 300 parents residing in Ordu who had children aged 0–66 months between February and April 2025. The sample was determined using the convenience sampling method. As data collection tools, a Personal Information Form prepared by the researcher and two scales were used. One of the scales employed in the study is the Child Neglect and Abuse Awareness Scale for Parents (CNAASP) developed by Ünal and Boz (2017) to measure parents’ awareness levels regarding child neglect and abuse. The scale consists of 45 items and five subdimensions. The other measurement tool is the Cognitions about Child Abuse Scale (CCAS), developed to determine individuals’ misconceptions, prejudices, and cognitive levels related to child neglect and abuse. This scale consists of three subdimensions and a total of 18 items. The data were analyzed using Independent Samples T-Test, ANOVA, Kruskal–Wallis, and Mann–Whitney U tests. According to the findings, parents awareness levels differed significantly in terms of gender, age, and education level, while there were no significant differences in relation to number of children or economic status. However, education level, economic status, and number of children were found to create significant differences in parents misconceptions, prejudices, and cognitive levels regarding child abuse. These results indicate that parents awareness and cognition levels related to child abuse and neglect are closely associated with sociodemographic factors.
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BİREYSEL İŞ HUKUKUNDA GENEL İŞLEM KOŞULLARI VE DENETİMİ
(Sosyal Bilimler Enstitüsü, 2023-09-27) KARAKAŞ SAYAN, İLKNUR; ATEŞ, DERYA; Özel Hukuk
Contracts containing general terms, the use of which became widespread with the Industrial Revolution, not only facilitated the working life, but also revealed the need to protect the other party of the contract due to the power imbalances that exist between the contracting parties. The general terms are defined between Articles 20 to 25 of the Turkish Code of Obligations. These conditions are also applicable to all employment contracts. General labor terms refer to the application of general terms in the contractual sources of labor law. These contractual sources of labor law include collective bargaining agreements, employment agreements, type employment agreements, internal regulations, and workplace practices. It is important to regulate the general working conditions that are widely used in employee-employer relations in favor of employees. It is important to control the general labor terms, which are widely used in employee-employer relations, and to protect the worker against these terms. In this study, due to the fact that the general labor terms are regulated in a general law, the problem of compliance, use and supervision of its provisions with the purpose and spirit of the Labor Law is discussed.