Hacettepe Üniversitesi Açık Erişim Sistemi (HÜAES)
- HÜAES, Hacettepe Üniversitesi bünyesinde üretilen kitap, makale, tez, bildiri, rapor gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, etkisini artırmak için telif haklarına uygun olarak Açık Erişime sunar.
Communities in DSpace
Select a community to browse its collections.
- Ankara State Conservatory
- Directorates
- Faculty of Dentistry
- Faculty of Pharmacy
- Faculty of Letters
Recent Submissions
Hacettepe Üniversitesi İç Hastalıkları Yoğun Bakım Ünitesinde İzlenen Hastalarda Kronik Kritik Hastalık Ve Persistan İnflamasyon İmmünsüpresyon Ve Katabolizma Sendromu Prevalansının Araştırılması
(Tıp Fakültesi, 2025-10-14) Şahin Mehmet Ali; Halaçlı Burçin; İç Hastalıkları
Advances in intensive care have increased survival from the acute phase of critical illness. However, this has also led to a large and growing population of chronically ill patients who remain dependent on prolonged mechanical ventilation (MV) and other intensive care therapies, requiring multiple organ support. This condition, termed chronic critical illness (CCI), imposes a substantial burden on health systems (1). There is no universally accepted definition of CCI in the literature. Our study aimed to compare the prevalence and patient characteristics according to four commonly used CCI definitions among patients admitted to the Internal Medicine Intensive Care Unit at Hacettepe University. We also examined the characteristics of patients with Persistent Inflammation, Immunosuppression, and Catabolism Syndrome (PIICS), a subgroup within CCI. Between 10/01/2023 and 03/31/2025, of 1,074 patients admitted to the Internal Medicine ICU, 823 were included after excluding inter-hospital transfers (n=22) and readmissions (n=229). Patients were evaluated according to four previously defined CCI definitions and CCI prevalence rates were determined. The four CCI definitions were as follows: CCI-1: need for MV (≥6 hours/day) for ≥21 days (2); CCI-2:
requirement for MV for 14–21 days or longer, or tracheostomy (3); CCI-3: ICU length of stay ≥8 days with at least one of the following: MV (≥96 hours in a single episode), tracheostomy, stroke, head trauma, sepsis, or major trauma (4); CCI-4: ICU stay ≥14 days and, on day 14, cardiovascular SOFA score ≥1 and/or other component scores ≥2 (5). PIICS diagnostic criteria: ICU length of stay ≥14 days; CRP >150 μg/dL; total lymphocyte count <0,80 ×10⁹/L; serum albumin <3,0 g/dL; prealbumin <10 mg/dL; creatinine increase index <80% (6). Of the 823 included patients, 460 (55.89%) were male. The median age was 67 years (IQR 54–77). CCI prevalence was: CCI-1, 5.47% (n=45); CCI-2, 9.36% (n=77); CCI-3, 24.18% (n=199); and CCI-4, 19.68% (n=162). PIICS prevalence was 8.26% (n=68). Among patients meeting CCI-4 criteria, the prevalence of PIICS was 41.97%. In multivariable and machine-learning analyses, the prominent parameters for CCI-3, CCI-4, and PIICS included APACHE II score, SOFA, endotracheal intubation within the first 24 hours, presence of neurological disease, hypoalbuminemia, CRP/procalcitonin, BUN/creatinine, PaCO₂, and elevated lactate. This study is the first to prospectively compare CCI definitions and prevalence
and to evaluate PIICS prevalence in a medical ICU. The finding that different definitions yield different prevalence rates highlights the need for an ideal, easily applicable definition of CCI and underscores the necessity for further research focusing on PIICS.
Kronik hava yolu hastalıklarında spirometrik ölçütlerin değerlendirilmesi
(Tıp Fakültesi, 2023) Maide Gözde İnam; Göğüs Hastalıkları
Spirometry is the most commonly used repeatable pulmonary function test in the diagnosis and monitoring of lung diseases. Forced expiratory volume in the first second (FEV1), forced vital capacity (FVC) and FEV1 / FVC ratio are parameters that can be measured by spirometry and provide information about airway diseases. International guidelines have published standardization criteria for evaluating spirometric parameters. However, the test performed is dependent on the patient's effort and requires the patient's compliance while performing the test. The aim of this study is to develop physiological parameters related to airway diseases using spirometry measurements and to compare these parameters with existing spirometric parameters. In our study, the data of 12,326 spirometry tests were analyzed using mathematical modeling and newly defined parameters were examined with ROC curves. In the model, the area under the curve (AUC) was found to be 0.988 (95% confidence interval (CI) 0.986-0.990), (sensitivity (Se) 95% and specificity (Sp) 95%) for t2; 0.986 (95% CI 0.984-0.988) (Se 97%, Sp 92%) for t3; 0.929 (95% CI 0.922-0.935) (Se 88%, Sp 84%) for t4; 0.881 (95% CI 0.872-0.890) (Se 78%, Sp 82%) for t1 geometric mean (gmean); 0.849 (95% CI 0.839-0.859) (Se 75%, Sp 79%) for tp gmean; 0.912 (95% CI 0.905-0.919) (Se 85%, Sp 82%) for tq gmean (p<0.001 for all measurements). The t2 and t3 parameters were found to be more specific and sensitive than the maximal mid-expiratory flow (MMEF25-75%) value in detecting airway obstruction. Our research has shown that these parameters have a strong relationship with airway obstruction.
Ebeveynlerin Çocuk ihmal ve İstismarına Yönelik Farkındalık ve Biliş Düzeylerinin Değerlendirilmesi: Ordu İli Örneği
(Sosyal Bilimler Enstitüsü, 2026-01) Bulut Uçar Cansu; Sosyal Hizmet
The aim of this study is to examine the awareness and cognitive levels of parents with preschool children regarding child abuse and neglect in terms of various sociodemographic variables. The research was conducted using the relational survey model to determine the relationships among variables. The study was carried out on a sample consisting of parents with preschool children living in Ordu Province.The study group consisted of 300 parents residing in Ordu who had children aged 0–66 months between February and April 2025. The sample was determined using the convenience sampling method. As data collection tools, a Personal Information Form prepared by the researcher and two scales were used. One of the scales employed in the study is the Child Neglect and Abuse Awareness Scale for Parents (CNAASP) developed by Ünal and Boz (2017) to measure parents’ awareness levels regarding child neglect and abuse. The scale consists of 45 items and five subdimensions. The other measurement tool is the Cognitions about Child Abuse Scale (CCAS), developed to determine individuals’ misconceptions, prejudices, and cognitive levels related to child neglect and abuse. This scale consists of three subdimensions and a total of 18 items. The data were analyzed using Independent Samples T-Test, ANOVA, Kruskal–Wallis, and Mann–Whitney U tests. According to the findings, parents awareness levels differed significantly in terms of gender, age, and education level, while there were no significant differences in relation to number of children or economic status. However, education level, economic status, and number of children were found to create significant differences in parents misconceptions, prejudices, and cognitive levels regarding child abuse. These results indicate that parents awareness and cognition levels related to child abuse and neglect are closely associated with sociodemographic factors.
BİREYSEL İŞ HUKUKUNDA GENEL İŞLEM KOŞULLARI VE DENETİMİ
(Sosyal Bilimler Enstitüsü, 2023-09-27) KARAKAŞ SAYAN, İLKNUR; ATEŞ, DERYA; Özel Hukuk
Contracts containing general terms, the use of which became widespread with the Industrial Revolution, not only facilitated the working life, but also revealed the need to protect the other party of the contract due to the power imbalances that exist between the contracting parties. The general terms are defined between Articles 20 to 25 of the Turkish Code of Obligations. These conditions are also applicable to all employment contracts. General labor terms refer to the application of general terms in the contractual sources of labor law. These contractual sources of labor law include collective bargaining agreements, employment agreements, type employment agreements, internal regulations, and workplace practices. It is important to regulate the general working conditions that are widely used in employee-employer relations in favor of employees. It is important to control the general labor terms, which are widely used in employee-employer relations, and to protect the worker against these terms. In this study, due to the fact that the general labor terms are regulated in a general law, the problem of compliance, use and supervision of its provisions with the purpose and spirit of the Labor Law is discussed.
The Experimental Study Examining the Effect of Subject Area Knowledge on Translation Quality
(Sosyal Bilimler Enstitüsü, 2023) Baydan, Utku; Antonova Ünlü, Elena; Mütercim-Tercümanlık
This thesis aims to contribute to the research on the effect of subject area knowledge on
the quality of translation focusing on a sports field: football. An experiment was
conducted with a sample of university students in which they were divided into two
groups: the experimental group and the control group. During the experiment, both groups
took a pre-test translation task. Then, the experimental group participated in a 4-week
special training program in the field of football. The control group continued their normal
education in the department. Following the training program, both groups took a post-test
translation task. Results were evaluated in terms of three categories: translation quality,
terminology, and accuracy. The result of the pre-test translation task shows that there were
no significant differences between the two groups. However, the result of the post-test
translation task shows that there were significant differences between the two groups and
also there were significant differences between the pre-test and post-test translation
results of the experimental group. It was observed that experimental group participants
who went through the training program performed better results compared to control
group participants. This thesis aims to help emphasize the importance of subject area
knowledge training in the translation process by focusing on football which to my
knowledge, has not been studied in translation studies in terms of the effect of subject
area knowledge.