Preeklampsi Olan Annelerin Bebeklerinde Ortalama Trombosit Hacmi Değerleri ve Morbiditeler ile Ilişkisi

Abstract

Preeclampsia causes maternal and neonatal morbidities and mortalities as an incompletely solved and understood pregnancy complication. There are many of ongoing and finished studies which are trying to identify the pathogenesis of preeclampsia. Utero-placental dysfunction could be the reason of fetal and neonatal complications in preeclampsia, however the wonder about the etiology and pathogenesis of the disease motive us for evaluating preeclamptic mothers' babies. Recently it is known that mean platelet volume (MPV) in preeclamptic patients is higher nevertheless there are few studies related with this subject on preeclamptic mothers' babies. Preeclampsia is a systemic enflamatuar disease thus this study may guide us through the aspects of this enflamatuar structure whether positive or negative on fetal and neonatal systems. That retrospective study was held in Neonatal Intensive Care Unit of our hospital and consisted of 148 preeclamptic mothers' babies with 147 babies that their mother was not preeclampsia as a control group. Medical records of the patients were retrieved from the hospital database. In preeclamptic mothers' babies MPV and haemoglobin values were significantly higher than the control group (p<0.0001, p: 0.032) whereas platelet and white blood cell counts were significantly lesser than the control group (p: 0.002, p: 0.011). On the other hand birth weights were lower in preeclamptic mothers' babies group (p: 0.001) and the number of small for gestation age (SGA) babies were much more in that group (p<0.0001). Despite these findings there was not a significant difference in babies with prematurity complications like respiratory distress syndrome (RDS), necrotising enterocolitis (NEC), intraventricular hemorrhage (IVH) and patent ductus arteriosus (PDA); additionally MPV values of the babies with these morbidities were not also significantly different than the babies without morbidities.