Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Investigation show that glutathione and related enzymes are often overexpressed in tumor cells ...

In this thesis study, the molecularly imprinted glassy carbon and quartz crystal microbalance (QCM) nanosensors were developed for the determination of tobramycin. For QCM nanosensor, firstly the modification of gold surface ...

In this study, in order to investigate roles of certain genes and expression levels of these genes in apoptosis, MCF-7 (breast), HEPG2 (liver) cancer cells and HEK293 embryonic kidney cells were treated with increasing ...

To investigate effects of statins on cholinesterases, Butyrylcholinesterase (BChE; E.C.3.1.1.8 ) was purified from human plasma through acid dialysis, DEAE-Tris Acryl M ion exchange and Procainamide-Sepharose 4B chromatography ...

Development and Validation of an Ultra-Performance Liquid Chromatographic-Tandem Mass Spectrometry (UPLC-MS/MS) Method for Determination of Betamethasone or Dexamethasone in Pharmaceutical Preparations, Hacettepe University, ...

Signal trunsduction pathways play crucial roles in breast cancer pathogenesis. mTOR, which plays a central role in cell proliferation and interacts with several cell components, is selected as a target in MDA-MB- 231 ...

In various acute and chronic renal diseases, tissue damage occurs and platelet activation is observed. Recent studies suggest that some factors released from activated platelets may participate in inflammation and fibrosis ...

Acetylcholinesterase (AChE) in the serum of fetal bovine is a tetrameric enzyme. The related enzyme, butyrylcholinesterase (BChE), in the sera of humans and horse requires polyproline peptides for assembly into tetramers. ...

Cancer is one of the most dangerous fatal diseases threating the human being both economically and socially. Therefore, the studies are performed on molecular level to understand cancer on molecular level and prevent the ...

Raloxifene is selective estrogen modulator (SERM) drug which is used in the treatment of postmenopausal osteoporosis in women and used for doping in men. A new gas chromatography-mass spectrometry (GC-MS) method was developed ...