Browsing Biyomühendislik Bölümü by Issue Date
Now showing items 1-20 of 101
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Model Bir Yeşil Flöresan Protein İçin Aptamer Üretiminin ve Optik Biyosensörlerde Uygulanmasının Araştırılması
(Fen Bilimleri Enstitüsü, 2013)The purpose of this research is identification of the target molecule-aptamer complex model that can be used as a model system to establish a measurement standard for increasing the efficiency of the analytic performance ... -
Işık-Etkili Kemik Doku Mühendisliği
(Fen Bilimleri Enstitüsü, 2013)The purpose of this in vitro study is to investigate the biomodulatory effects of plasma arc welding (700-2500 nm, 650 W, 10-4 W cm2) on three-dimensional (3D) cell cultures and to evaluate the results for bone tissue ... -
Bir Lokal Anestezik Madde Olan Lidokain'in (2-Dıethylamıno-N-(2,6 Dımethylphenyl) Acetamıde) Etki Süresini Uzatmak için Poli Akrilat Bazlı Hidrojel Mikrokürelerin Kullanımı ve Denenmesi
(Fen Bilimleri Enstitüsü, 2013)Local anaesthetics are used in many space, especially surgial operation in small areas. However, their effect time is short, they need to be repeated continuously and this may cause toxicity that results in many problems. ... -
İlaç Salımı İçin Moleküler Baskılanmış Kriyojel Membranlar
(Fen Bilimleri Enstitüsü, 2013)The aim of the controlled drug delivery is to release drug with a therapeutic dose to the defined part of the body. Besides that, decreasing the side effects, providing a minimum dose usage and prolonging the pharmacological ... -
Üreteral Stentlerde Enfeksiyon Önleyici Antibakteriyel Fırça Tipi Polimer Aşılamanın Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2013)Ureteral stent aids the flow of urine and is profoundly used in the treatment of patients with urological disorders including obstructive uropathy (urological encrustation), ureteric injury, primary or malignant carcinomas, ... -
Nanopartiküller Kullanılarak Rf ile Hipertermi
(Fen Bilimleri Enstitüsü, 2013)Cancer is a one of the most important diseases of human being. Although a lot of progress have been achieved in the diagnosis and treatment of cancer, their current levels are not fully satisfying (Greenlee, Hill Harmon ... -
Biyomimetik Yöntemle Bor Katkılı Doku İskelelerinin Geliştirilmesi ve Kemik Doku Mühendisliğindeki Etkinliklerinin Araştırılması
(Fen Bilimleri Enstitüsü, 2013)This thesis was prepared with the support of TÜBİTAK Project, entitled Mikrodalga desteği ile Biyomimetik Hidroksiapatit (HAp)-Bor Katkılı HAp Oluşumu ve Kitosan-HAp Kemik Doku İskelelerinin Geliştirilmesi with the code ... -
Β-Estradiol Yüklü Doku İskeleleri ile In-Vitro Kemik Doku Mühendisliği
(Fen Bilimleri Enstitüsü, 2013)The aim of the present study was to develop a system of 17-β estradiol (E2) loaded poly (lactic-co-glycolic acid) PLGA nanoparticles-chitosan/hydroxyapatite (HA) tissue scaffold and to investigate the in-vitro effectiveness ... -
Pva Kopolimer-G-Pla Organik Kil Agno3 Nanokompozitlerinin ve Nanoliflerinin Sentezi, Karakterizasyonu ve Antibakteriyel Özellikleri
(Fen Bilimleri Enstitüsü, 2013)Recently, the different methods were developed for the fabrication of nanostructures, especially polymer nanofibers and application in bioengineering and tissue regeneration. Nanoscale images of polymer nanosystems and ... -
Kanser Hücrelerinin Aptamer ve Antibadi Taşıyan Manyetik Nanopartiküller ile Hedeflenmesi
(Fen Bilimleri Enstitüsü, 2014)Within the context of this thesis, developing of an early diagnosis nanoparticular system in order to detect and image human breast cancer cell line of MDA MB 231 is aimed. In this regard, gold coated superparamagnetic ... -
Development of Bacteriophage Nanoparticles for Glycomics Analysis by Genetic Engineering
(Fen Bilimleri Enstitüsü, 2014)The study is significant because it has overcome the current bottlenecks in glycan array construction and provide a relatively inexpensive, specific and stable glycan representation method, as well as introduce a simplified ... -
Yüzey Zenginleştirilmiş Raman Spektroskopisi (Sers) için Nano-Yaklaşım Temelli Platformların Geliştirilmesi ve Tanı Amaçlı Uygulanması
(Fen Bilimleri Enstitüsü, 2014)Surface-Enhanced Raman Spectroscopy (SERS) has attracted increasing interest as a powerful analytical tool for the detection of chemical and biological molecules since its discovery. In SERS studies, the enhancement of ... -
Biyofiziksel ve Biyokimyasal Uyaranlarla Desteklenmiş Doku İskeleleri ile Mezenkimal Kök Hücrelerin Osteojenik Farklılaşmasının İncelenmesi
(Fen Bilimleri Enstitüsü, 2014)The aim of this study is to investigate the osteogenic differentiation potential of mesenchymal stem cells in the presence of biophysical and biochemical stimulants by using different biomaterials. For this purpose, ... -
Cytochrome C Purıfıcatıon with Surface Imprinted Bacterial Cellulose Nanofibers
(Fen Bilimleri Enstitüsü, 2014)In the present study, cytochrome c imprinted bacterial cellulose (Cyt c-MIP)nanofibers were prepared for the purification and recognition of cytochrome c viasurface imprinting approach. N-methacryloyl-L-histidine methyl ... -
Kolon Kanser Hücreleri İçin Altın Kaplı Manyetik Yüklü Transfeksiyon Ajanlarının Kullanılması
(Fen Bilimleri Enstitüsü, 2014)Cancer is still one of the most important problems of mankind s health that cause to death. There is a significant portion of spendings in the health sector. The early diagnosis and treatment of cancer and the budgets spent ... -
İnsan Dermal Fibroblast ve Keratinositlerini İçeren Kitosan-Jelatin Fibrin Yapıştırıcı Esaslı İki Tabakalı Yapay Deri Sisteminin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2014)In this study, we aimed to obtain an artificial bilayer skin substitute by combining human dermal fibroblasts (Detroit 551) cultured on chitosan-gelatin superporous hydrogels (SPHs) as a dermal layer and human keratinocytes ... -
Nanopartiküller ile Modifiye Edilmiş Karbon Elektrotlarla Elektrokimyasal Tanı
(Fen Bilimleri Enstitüsü, 2015)In this study, new surfaces for pencil graphite electrodes with high stability, high surface area and highly catalytic activity were developed by coating them firstly with polydopamine, then with gold and silver nanoparticles. ... -
Mikrobiyal Hava Toplayıcı ve Okuyucu Sistemi Tasarımı ve Prototip Üretimi
(Fen Bilimleri Enstitüsü, 2015)The detection of air purifier or air pollution is very important step to take necessary precautions to prevent infections. Nowadays, partical measuring and passive air sampling methods are widely used to detect air pollution ... -
Kemik Doku Implant Malzemeleri: Osseointegrasyon ve Antibakteriyel Etkinlik
(Fen Bilimleri Enstitüsü, 2015)This study aims to improve antibacterial titanium coating which enhanced osseointegration at the same time. Titanium (Ti) substrates covered with antibacterial polyethylene oxide (PEO) fibers which have functionalized with ... -
Ccp Antikorlarının Tayini için Yüzey Plazmon Rezonans Temelli Biyosensörlerin Hazırlanması
(Fen Bilimleri Enstitüsü, 2015)Rheumatoid arthritis (RA) suffers up to 1% of the world's population, affecting females to a greater extent (3–5 fold) than males. RA mainly affects joints, also has systematic effects on body. The most commonly performed ...
