2-Hidroksiizokaproik asitin kök kanalından uzaklaştırılabilirliğinin ve MTA’nın bağlanma dayanımına etkisinin incelenmesi

Abstract

The aim of this study was to evaluate the removal of 2-Hydroxyisocaproic acid (HICA) from the root canal space and its effect on the bond strength of the mineral trioxide aggregate (MTA) in comparison with double antibiotic paste (DAP) and calcium hydroxide (CH). In this study, 126 single-canal teeth were selected. After decoranization of teeth, they were instrumented with ProTaper rotary system and #1 to #6 Peeso reamers in order to obtain a standard internal diameter and stimulate immature teeth model. Teeth were randomly divided into 3 experimental groups (n=108) that were treated with DAP, HICA, and CH. 18 teeth were used as a control group. After 3 weeks, 18 teeth from each experimental group (n=54) were examined within the scope of the removal of HICA from the root canal. The remaining intracanal medicaments were determined with Image J software using polygons and measured. 72 teeth (3 experimental groups and a control group) were used within the scope of the evaluation of the bond strength of the MTA. Following the removal of the intracanal medicaments, MTA was applied into the coronal 4 mm. The bond strength between MTA and dentin was measured by using push-out test. Moreover, failure types were also recorded. Data were statistically analysed. There was no statistically significant difference between HICA, DAP, and CH groups in terms of removability (p>0.05). Bond strength of the MTA had significantly less in the HICA group compared to other groups (p<0.05). There was a predominance of mix failures between root dentin and MTA. Acoording to the results of this study, DAP, HICA and CH could not be removed entirely from root canal space. HICA had significantly lower bond strength values than DAP and CH. Despite the high antibacterial properties of HICA and its low cytotoxic effect on pulp cells, the effect of reducing bond strength of the MTA should be considered while using HICA in regenerative treatments.