Eczacılık Meslek Bilimleri Bölümü Tez Koleksiyonu
Güncel Gönderiler
-
Fruktozla indüklenen hipertansif sıçan modelinde nöroinflamasyon ve artmış kan basıncı üzerine mikroglial inhibisyonun etkisi.
(Sağlık Bilimleri Enstitüsü, 2024)Neuroinflammation and increased sympathetic activity are at the forefront of the neurogenic etiology of hypertension. Microglia, the structural immune cells of the brain, plays a critical role in the inflammatory process ... -
MYRTUS COMMUNIS L. ÜZERİNE FARMASÖTİK BOTANİK ARAŞTIRMALAR
(Sağlık Bilimleri Enstitüsü, 2024-09-23)Myrtus communis L., a member of the Myrtaceae family, is a naturally growing, evergreen plant in our country. It is used internally in stress management, diabetes treatment, wound healing, cholesterol lowering, diarrhea ... -
Linaria corifolia Desf. Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2024-09-16)Linaria Mill. genus that is a member of the Plantaginaceae family is widely found in our country. There are approximately 200 species of Linaria in the world, 21 in Turkey, and 12 of them are endemic. Linaria species, ... -
ANTİMİKROBİYAL TEDAVİDE İNTRAVENÖZDEN ORALE GEÇİŞ PROTOKOLÜ GELİŞTİRİLMESİ VE UYGULAMASININ GEÇİŞE ETKİSİ VE KLİNİK ECZACININ ROLÜ
(Sağlık Bilimleri Enstitüsü, 2024)In antimicrobial treatment, it is recommended to switch from intravenous to oral therapy in eligible patients to reduce complications and ensure pharmacoeconomic treatment. In this study, we evaluated the effect of a ... -
DOĞAL VE SENTETİK ENDOKRİN BOZUCU KİMYASAL MADDELERİN 3T3- L1 HÜCRELERİNDE ADİPOJENEZLE İLGİLİ PROTEİNLER ÜZERİNDEKİ TOKSİK ETKİLERİNİN KARŞILAŞTIRMALI OLARAK DEĞERLENDİRİLMESİ
(Sağlık Bilimleri Enstitüsü, 2024)Bilinmiş, İ. Comparative Evaluation of the Toxic Effects of Natural and Synthetic Endocrine Disrupting Chemicals on Adipogenesis-Related Proteins in 3T3-L1 Cells, Hacettepe University Graduate School of Health Sciences ... -
In Silico Toksikoloji Yöntemleri ve Uygulamaları Üzerine Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2024)The use of computer-assisted toxicology methods (in silico toxicology, computer-based toxicology etc.) in predicting preclinical toxicological endpoints, clinical side effects, and the metabolism of pharmaceutical ... -
Endokannabinoid Metabolizmasının İnhibisyonunun Alerjik Solunum Yolu İnflamasyonunda Yeni Bir Tedavi Stratejisi Olarak İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2024-07-10)Endocannabinoids are biologically active endogeneous substances with a cannabinoid structure. Their degradation is primarily carried out by two enzymes: fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). ... -
Romatoloji Kliniğinde Takip Edilen Hastalarda Glukokortikoid Tedavisinin İzlemi
(Sağlık Bilimleri Enstitüsü, 2024)Glucocorticoid toxicity index (GTI) is an assessment tool that measures glucocorticoid-related toxicity and its change over time. This study aimed to assess the glucocorticoid therapy of patients in a rheumatology outpatient ... -
Overektomi Uygulanan Sıçanların Detrusor Düz Kasında Hücre İçi Kalsiyum Hareketleri Üzerinde Hidrojen Sülfürün Etkisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2024)Women experience incontinence during menopause, as a result of the decrease in estrogen levels due to aging. Hydrogen sulfide is an endogenous gasotransmitter which has relaxant effect on detrusor smooth muscle and estrogen ... -
Sıçanlarda Subakut Alkol Kullanımına Bağlı Gelişen Karaciğer Fibrozisinde İdebenon ve Koenzim Q10’un Etkisinin NLRP3 İnflamazom Aktivitesi Üzerinden İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2024-06-13)YOLADI, F.B., Investigation of the Effects of Idebenone and Coenzyme Q10 on Liver Fibrosis Due to Subacute Alcohol Use in Rats through NLRP3 Inflammasome Activity, Hacettepe University Graduate School of Health Sciences, ... -
Gentiana olivieri Griseb.’in Nöroprotektif Etkisi
(Sağlık Bilimleri Enstitüsü, 2024-06-25)The genus Gentiana has 400 species in the world and 12 species in Türkiye, and plants belonging to this genus have had a wide range of uses in folk medicine for many years. Gentiana olivieri Griseb. used in Southeastern ... -
Sıçan İzole Torasik Aortunda Perivasküler Adipoz Doku Fonksiyonundaki Yaşa Bağlı Değişimin In Vıtro ve In Vıvo Çalışmalarla Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2024)Perivascular adipose tissue (PVAT) is the layer of fat surrounding the outside of blood vessels and contributes to the control of vascular tone through the release of relaxing factors that exhibit anticontractile effects ... -
Elazığ Bölgesi Siyah Üzümünün (Vitis Vinifera L.) Endüstriyel Atıklarından Yüksek Saflıkta Resveratrol Elde Edilmesi
(Sağlık Bilimleri Enstitüsü, 2024)Akcan, A.Y., Obtaining High Purity Resveratrol from Industrial Wastes of Black Grapes (Vitis Vinifera L.), Hacettepe University, Graduate School of Health Sciences, Pharmacognosy Program, Master of Science Thesis, Ankara, ... -
Verbascum uschakense (Murb.) Hub.-Mor. Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2024)Mındız R.S., Pharmacognostical Researches on Verbascum uschakense (Murb.) Hub.-Mor. Hacettepe University, Graduate School of Health Sciences, Pharmacognosy Program, M. S. Thesis, Ankara, 2024. Verbascum L., the largest ... -
Son Dönem Böbrek Yetmezliği Hastalarında Olası Genotoksik Hasarın Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2024-02)Chronic kidney disease is a common progressive disease characterized by the permanent loss of functional nephrons. End-stage renal failure (ESRD) is known to be an irreversible disease. There is some debate as whether the ... -
Türkiye’de Yetiştirilen Bazı Arachis hypogaea L. (Yer Fıstığı) Çeşitlerinin Farklı Ekstrelerinde Trans-Resveratrol ve Polidatin Analizi
(Sağlık Bilimleri Enstitüsü, 2024)Arachis hypogaea L. is the only cultivated peanut species in the Fabaceae family. There are phytochemical analyses for various organs of peanut in the literature. As a result of these analyses, phytosterols, anthraquinones ... -
Azol Halkası Taşıyan COX İnhibitörlerinin Sentezi ve Antimikrobiyal Aktivitelerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2024-01)Nonsteroidal anti-inflammatory drugs (NSAIDs) are the group of drugs that show their effects by inhibiting cyclooxygenase (COX) enzymes and are frequently used in the treatment of pain and inflammation. In addition to these ... -
Pitavastatinin Sisplatin ile Birlikte Antikanserojen Etkilerinin İnsan Serviks Kanser Hücrelerinde Araştırılması
(Sağlık Bilimleri Enstitüsü, 2024-01-18)Cervical cancer is one of the most widespread malignant tumors in women around the world today. Pitavastatin is a 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitor widely used to treat hypercholesterolemia and ... -
Alzheimer Hastalığının in vitro Modellerinde Herpes Simpleks Proteinlerinin Kompleman Sistem, Sitokinler ve Epigenetik Değişiklikler Üzerindeki Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2023)Alzheimer's disease (AD) is characterized by decline in cognitive functions and dementia. Most cases are sporadic. However, some of these cases may develop from genetic or epigenetic origins. Additionally, it has been ... -
Investigation of Possible Protective Effects of Certain Xenobiotics on Aluminum Toxicity in SH-SY5Y Cell Line
(Sağlık Bilimleri Enstitüsü, 2023-11-16)Aluminum, a neurotoxic metal, is widely present in our daily lives, exposing us extensively. Aluminum exposure is a potential Alzheimer's risk factor, with no cure yet. Researchers are actively seeking new treatments or ...
RSS 1.0