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Toplam kayıt 7, listelenen: 1-7
Hücre Tabaka Mühendisliği ile Göbek Kordonu Perisitlerinden Üç Boyutlu Damar Grefti Eldesi
(Sağlık Bilimleri Enstitüsü, 2018-01-25)
In the case of limited accessibility of the autologous vessels and the disadvantages of synthetic scaffolds, small-diameter vascular grafts (SDVG) made from cellularized natural scaffolds are needed for the treatment of ...
Değişik Kaynaklı MKH’lerin Detaylı Karakterizasyonu, Lenfohematopoezi Destekleyici Özellikleri ve İzolasyonunda CD271 Antijeninin Önemi
(Sağlık Bilimleri Enstitüsü, 2018)
Mesenchymal Stem Cells (MSCs) are multipotent cells with self-renewal ability and form the basis for regenerative treatments. CD271 antigen is an effective marker for isolation of pure populations of MSCs from bone marrow ...
Eritropoetin Uygulamasının Mezenkimal Kök Hücre Gen ifade Profiline Etkisi
(Sağlık Bilimleri Enstitüsü, 2018)
Mesenchymal Stem Cells (MSC) have therapeutic importance because of their multipotency and immune modulation potentials. Erythropoietin is responsible for erytropoesis. However, EPO treatment of cells including mesenchymal ...
Griscelli Sendromu Uyarılmış Pluripotent Kök Hücre Geliştirilmesi, Karakterizasyonu ve İn Vitro Hematopoetik Farklılaşması
(Sağlık Bilimleri Enstitüsü, 2018-04-04)
Griscelli type 2 Syndrome (GS-2) is a rare, autosomal recessive
immune deficiency syndrome. The RAB27A gene mutation in GS-2 patients results in
the loss of function of T and NK cells. Induced pluripotent stem cells ...
İn Vitro Kültür Ortamında Kemik İliği Nişi Modellenmesine Yönelik Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2018)
Mesenchymal stem cells (MSC) are the widely used stem cell type in preclinical research, clinical studies and investigational new drug applications. Isolation of MSC can be provided from bone marrow and adipose tissue, and ...
Mezenkimal Kök Hücrelerin Diamond Blackfan Anemisi Hastalığındaki Rolünün Aydınlatılması
(Sağlık Bilimleri Enstitüsü, 2018-07)
In this thesis, the molecular etiology of Diamond Blackfan Anemia is tried to be enlightened. For this purpose, bone marrow mesenchymal and hematopoietic stem cells from the patients were comparatively analyzed with healthy ...
Hox and Tale Transcrıptıon Factors in Fanconı Anemıa Bone-Marrow Mesenchymal Stem Cells: Gene Expressıon and Proteın Interactıons
(Sağlık Bilimleri Enstitüsü, 2018)
HOX/TALE proteins maintain tissue identity and their altered expression is seen in many cancers. The main aim of this thesis is to evaluate whether HOX/TALE gene expression changes due to genomic instability. To answer ...