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Development And Characterisation Of Magnetically Responsive And Active Agent Loaded Alginate Based Microspheres To Be Used In The Treatment Of Hepatocellular Carcinoma (Hcc)
(Fen Bilimleri Enstitüsü, 2019)
Today, cancer is the foremost common and deadly disease in the world. One of the most important cancer types is liver cancer and occurs either by being directly involved with liver cells resulting in primary liver cancers, ...
3 Boyutlu Yazıcı ile Metakrilatlanmış Jelatin/PRP Hidrojel ve Mezenkimal Kök Hücre İçeren Osteokondral Gradyan Sistemlerin Hazırlanması ve in-Vitro Etkinliklerinin Belirlenmesi
(Fen Bilimleri Enstitüsü, 2019)
The aim of the presented doctoral thesis is to develop a gradient hydrogel system which loaded adipos tissue derived stem cells (AdMSCs) by using photoactivated platelet-rich plasma (PRP) gradient and 3D bioprinting method ...
Hücre Tabakası Mühendisliğinde Kalınlık ve Vaskülerizasyon Problemlerine Yönelik Stratejilerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)
In the context of tissue engineering studies, various biomaterials, cells and biosignal
molecules have been used to repair and replace diverse tissues either alone or in
combination, namely to produce tissue-engineered ...
E. coli Tayini İçin Altın Selüloz Nanofibril Materyal Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)
In this thesis, a method for the detection of Escherichia coli (E. coli) bacteria was developed using Raman techniques and Raman mapping methods. Firstly, gold nanorod particles were synthesized and subsequently surface ...
Nerve Guidance Conduit Application Of Magnesium Alloys
(Fen Bilimleri Enstitüsü, 2019)
Surgery is insufficient for peripheral nerve injuries larger than 5 mm. Function loss and scar formation occur as a result of slow healing rate and inflammation cells filling the damaged gap. Therefore, isolation of damaged ...
Adipoz Kökenli Mezenkimal Kök Hücrelerin Polietilenglikol Dimetakrilat Hidrojellerde Kahverengi ve Beyaz Adipoz Dokuya Farklılaşmalarının İncelenmesi
(Fen Bilimleri Enstitüsü, 2019-02)
This study was financially supported by Hacettepe University Scientific Research Projects Coordination Unit with a graduate project entitled “Investigation of Brown and White Adipose Tissue Differentiation of Adipose Derived ...
Karaciğer Tümörlerinin Tedavisinde Uygulanacak Y-90 Mikrokürelerin Aktivite Miktarlarının Hastaya Özgü Modelleme İle Belirlenmesi İçin Yöntem Geliştirilmesi ve Yöntemin Standardize Edilmesi
(Fen Bilimleri Enstitüsü, 2019)
Yttrium-90 (Y-90) microsphere treatment is the internal radionuclide treatment through administration of Y-90 loaded microspheres to the tumor microcirculation via the relevant branch of the hepatic artery feeding the ...
Poli(Poliol)Sebakat Bazlı Biyobozunur Elastomerlerin Sentezi ve Jiro Eğrilmiş Fiber Destekli Hidrojel Doku İskelelerinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)
Poly(polyol) sebacate (PPS) based polymers are promising polymers in biomedical and tissue engineering field, thanks to tunable mechanical properties and having biodegradable and biocompatible features. However, difficult ...
Hücrelerinden Arındırılmış Miyokardiyal Doku İle Hücre Tabakası Destekli Kalp Yaması Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019-02)
The aim of this thesis is to produce a heart patch by combining cardiovascular cell sheet and decellularized myocardial extracellular matrix (ECM). In the study, two innovative approaches of tissue engineering, ‘‘cell sheet ...
Kemik Çimentolarında Yumurta Kabuğu Zarı Proteininin Kullanımı
(Fen Bilimleri Enstitüsü, 2019-10-07)
Within the scope of the presented thesis, it is thought that protein doped bone cements promise potential in terms of biodegradability and strength. Therefore, by adding protein to calcium sulphate based bone cements (CSC), ...