Ara
Toplam kayıt 103, listelenen: 71-80
MEME KANSERİ HÜCRELERİNE mTOR ANTİSENS OLİGONÜKLEOTİTLERİNİ HEDEFLEYECEK TRANSFERRİN KAPLANMIŞ ALTIN NANOPARTİKÜLLERİN TASARIMI SENTEZİ VE UYGULANMASI
(Fen Bilimleri Enstitüsü, 2017-10)
Breast cancer is the most frequent cancer in women. The type and molecular characteristics of breast cancer determines prognosis and helps design effective therapy regimes. mTOR, the mammalian target of Rapamycin is one ...
Serpınb1 Ve Serpınb2 Proteaz İnhibitörlerinin Bronş Epitel Hücrelerindeki İnflamatuvar Cevaptaki Rolü
(Fen Bilimleri Enstitüsü, 2018)
Asthma is a serious health problem affecting nearly 300 million people worldwide.
Asthma frequency varies based on countries and even based on regions of same
country. For example, Australia and New Zealand have a frequency ...
Salinomisin ve BnHAp Yüklü Doku İskelelerinin Antikanserojen ve Antibakteriyel Etkinliğinin Araştırılması
(Fen Bilimleri Enstitüsü, 2018)
In the scope of the thesis, it is aimed to investigate the synergistic effect of an anticancer drug, salinomycin, loaded poly (lactic-co-glycolic acid) (PLGA 65:35) nanoparticles with the boron doped nanohydroxyapatite ...
Bor İçeren Nano Hidroksiapatit Kompozitlerin Kemik Hücrelerindeki Moleküler Etki Mekanizmasının Araştırılması
(Fen Bilimleri Enstitüsü, 2018)
The structure of the bone and the self-renewal capacity are damaged by metabolic diseases
and damages. The trace elements and hydroxyapatite crystals in the bone are important in
the development of biomaterials to support ...
Pva Kopolimer-G-Pla Organik Kil Agno3 Nanokompozitlerinin ve Nanoliflerinin Sentezi, Karakterizasyonu ve Antibakteriyel Özellikleri
(Fen Bilimleri Enstitüsü, 2013)
Recently, the different methods were developed for the fabrication of nanostructures, especially polymer nanofibers and application in bioengineering and tissue regeneration. Nanoscale images of polymer nanosystems and ...
İnsan Dermal Fibroblast ve Keratinositlerini İçeren Kitosan-Jelatin Fibrin Yapıştırıcı Esaslı İki Tabakalı Yapay Deri Sisteminin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2014)
In this study, we aimed to obtain an artificial bilayer skin substitute by combining human dermal fibroblasts (Detroit 551) cultured on chitosan-gelatin superporous hydrogels (SPHs) as a dermal layer and human keratinocytes ...
Sferoid Yüklü Ecm-Mimetik Peptit Amfifil Hidrojellerle Çip-Üstü-Karaciğer Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2018-06-28)
This study was financially supported by Hacettepe University Scientific Research Projects Coordination Unit with a project entitled “Development of the liver-on-chip to be used in determining the toxicity of drugs” (project ...
Manyetik Silika Bazlı Borat Afinite Kromatografisi Sorbentlerinin Sentezi Ve Kromatografik Performanslarının İncelenmesi
(Fen Bilimleri Enstitüsü, 2018-06)
In this study, β-nicotinamide adenine dinucleotide (β-NAD) was molecularly imprinted onto plain and magnetic silica microspheres in the monodisperse-porous form, by core-shell polymerization method. For this purpose, ...
Preparation and Investigation of Ph-Sensitive Hydrogels/ Nanopartıcles for Drug Delivery
(Fen Bilimleri Enstitüsü, 2018)
Oral administration of the drugs is considered as one of the most convenient and comfortable routes. However, an effective oral delivery of insulin still remains a challenging and elusive goal, due to bioavailability ...
MANYETİK VE MANYETİK OLMAYAN SİLİKA BAZLI SABİT FAZLAR KULLANAN DNA MİKROEKSTRAKSİYON SİSTEMLERİNİN GELİŞTİRİLMESİ
(Fen Bilimleri Enstitüsü, 2017)
Monodisperse-porous silica microspheres and their magnetic form were synthesized by a newly developed” staged shape templated hydrolysis and condensation protocol”. The human genomic DNA isolation capacity from whole blood ...