• Bilateral Temporal Bone Xanthomas in Type II Hypercholesterolemia 

      Türk, Cezmi; Bilginer, Burçak; Benli, Kemal; Yavuz, Kıvılcım; Sağlam, Arzu; Ziyal, İbrahim M. (Turkish Neurosurgical Soc, 2010)
      We present a very rare case of intracranial xanthoma with bilateral temporal bone involvement. The lesion caused destruction and remodelling in mastoid air cells. On the right side, cerebellar compression was obvious. The ...
    • Improving Microcirculatory Reperfusion Reduces Parenchymal Oxygen Radical Formation And Provides Neuroprotection 

      Taşkıran, Aslıhan; Yemişçi Özkan, Müge; Özdemir, Yasemin; Erdener, Sefik Evren; Karataş, Hülya; Yüce, Deniz; Dalkara, Turgay (Lippincott Williams & Wilkins, 2018)
      Background and Purpose-Reperfusion is the most significant determinant of good outcome after ischemic stroke. However, complete reperfusion often cannot be achieved, despite satisfactory recanalization. We hypothesized ...
    • Inadequate Brain Glycogen Or Sleep Increases Spreading Depression Susceptibility 

      Kılıç, Kıvılcım; Karataş, Hülya; Dönmez Demir, Buket; Eren Koçak, Emine; Gürsoy Özdemir, Yasemin; Can, Alp; Petit, Jean-Marie; Magistretti, Pierre J.; Dalkara, Turgay (Wiley, 2018)
      Objective: Glycogen in astrocyte processes contributes to maintenance of low extracellular glutamate and K+ concentrations around excitatory synapses. Sleep deprivation (SD), a common migraine trigger, induces transcriptional ...
    • Inhibiting 12/15-Lipoxygenase To Treat Acute Stroke In Permanent And Tpa Induced Thrombolysis Models 

      Karataş, Hülya; Leyen, Klaus van; |Jung, Joo Eun; Lo, E. H. (Elsevier Science Bv, 2018)
      12/15-Lipoxygenase (12/15-LOX) contributes to the brain damage after middle cerebral artery occlusion (MCAO) in the acute phase of stroke. The aim of this study was to investigate the effects of a 12/15-LOX inhibitor, ...
    • Thrombotic Distal Middle Cerebral Artery Occlusion Produced By Topical Fecl3 Application: A Novel Model Suitable For Intravital Microscopy And Thrombolysis Studies 

      Karataş, Hülya; Erdener, Şefik Evren; Gürsoy Özdemir, Yasemin; Gürer, Günfer; Söylemezoğlu, Figen; Dunn, Andrew K.; Dalkara, Turgay (Nature Publishing Group, 2011)
      Intravital or multiphoton microscopy and laser-speckle imaging have become popular because they allow live monitoring of several processes during cerebral ischemia. Available rodent models have limitations for these ...
    • What is a Pericyte? 

      Mishra, Anusha; Attwell, David; Hall, Catherine N.; O'Farrell, Fergus; Dalkara, Turgay (International Society for Cerebral Blood Flow & Metabolism, 2016)
      Pericytes, spatially-isolated contractile cells on capillaries, have been reported to control cerebral blood flow physiologically, and to limit blood flow after ischaemia by constricting capillaries and then dying. ...