Başlık için Temel Tıp Bilimleri Bölümü Tez Koleksiyonu listeleme
Toplam kayıt 289, listelenen: 112-131
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Investigating the Effects of Neurometabolic Disease-Causing Genes on Synapse Function in Drosophila melanogaster
(Sağlık Bilimleri Enstitüsü, 2022)Our group has identified several patients that harbor mutations in genes that hold the potential for being important players of synapse function, UNC79 and MBOAT7 being two of them. UNC79 is one of the accessory ... -
Investigation of the Role of LAP1B in Transcriptional Regulation of Muscle Cells
(Sağlık Bilimleri Enstitüsü, 2021-01-20)The loss-of-function of the inner nuclear membrane protein LAP1B (lamina-associated polypeptide 1, isoform B) causes muscular dystrophy and cardiomyopathy in humans. The function of LAP1B in muscle is still unknown. The ... -
Investıgatıon of The In Vıtro And In Vıvo Effects of Telomere-Targeted New Drug Candıdate Compounds on Dıfferent Cancer Cell Lınes
(Sağlık Bilimleri Enstitüsü, 2023)Cancer, characterized by its heterogeneity, metastatic character, and limited treatability, stands as a leading global cause of mortality. Cancer cells elongate their telomeres through the activity of the telomerase enzyme, ... -
İkinci Trimesterde Sağlıklı Ve Kromozomal Anomalili Gebeliklerde Fetal Nazal Kemik, Ense Katlantısı, Böbrek, Karaciğer, Barsak, Plasenta ve Maternal Uterus Kas Tabakasının B-Mod Histogram ve Shear Wave Elastogram Yöntemleri ile İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023)B-mode ultrasonography is utilized in fetal screening of chromosomal abnormalities like Down Syndrome. Presence of soft markers such as hyperechogenic bowel, renal pelviectasis, hypoplastic nasal bone and increased nuchal ... -
İlaç Yeniden Konumlandırma Yaklaşımı ile Alfa Tübülin Asetilasyonunu Arttırabilecek Bileşiklerin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2020)Drug repurposing approach is used to identify new indications of drugs outside the scope of their original indications. This approach has been used to identify effective compounds for neurodegenerative diseases. Axonal ... -
İleri Yaşam Desteği Simülasyonunun Tıp Fakültesi Son Sınıf Öğrencilerinin Özyeterlik Algısına Etkisinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Evaluation Of The Effect Of Advanced Life Support Simulation On Final-Year Medical Students' Self-Efficacy Perceptions, Hacettepe University, Graduate School of Health Sciences, Medical Education Doctoral Thesis, Ankara, ... -
İnflamasyon İle İlişkili Nöromüsküler Hastalıklarda Dolaşımdaki Mitokondriyal DNA'nın Araştırılması
(Sağlık Bilimleri Enstitüsü, 2019)Neuromuscular diseases, mostly being among the rare genetic diseases, include a wide range of syndromes and diseases in which directly or indirectly skeletal muscle structure and function are affected. Recent scientific ... -
İnflamatuvar Hücre Göçü Sürecinde Pyrin ve Aktin İle Ilişkili Proteinlerin Moleküler Analizi
(Sağlık Bilimleri Enstitüsü, 2014)MEFV gene, encodes Pyrin protein, cause familial Mediterranean fever (FMF). Pyrin which is primarily expressed in neutrophils and monocytes, appears to be a regulator of inflammation, but its exact role on FMF pathophysiology ... -
İnsan Granüloza Hücresi Mitokondriyon Fonksiyonu ile AMH ve Östrojen İlişkisi
(Tıp Fakültesi, 2021)Anti-Müllerian Hormone (AMH) and estrogen are essential hormones in human ovarian folliculogenesis. AMH and estrogen are produced by granulosa cells. It is known that mitochondria in human granulosa cells are important for ... -
İnsan Kaynaklı Kistik Ekinokokkozis'in Moleküler Epidemiyolojisi
(Sağlık Bilimleri Enstitüsü, 2017)Cystic Echinococcosis (CE) is a zoonotic disease caused by larval forms of parasites of the genus Echinococcus in humans. CE is one of the most common zoonotic diseases in the world, particularly in regions where the local ... -
İnsan Serebral Mikrovasküler Endotel Hücrelerinin T Hücre Ko-İnhibisyonuna Etkisi
(Sağlık Bilimleri Enstitüsü, 2022)With continuous stimulation, naive T helper cells (Th) convert into effector and exhausted Th cells with low cytokine production and proliferation capacity. In addition, during this differentiation process, there are ... -
İnsan Serum Bütirilkolinesterazının Olası Lipolitik Aktivitesi-Lipid Metabolizması ile İlişkisi.
(Sağlık Bilimleri Enstitüsü, 2021-01-21)Cholinesterases (AChE and BChE) terminate acetylcholine-induced neurotransmission at cholinergic synapses in muscle-nerve junctions. We previously showed BChE expression is regulated by essential fatty acids. The similarity ... -
İnterstisyel Akciğer Hastalığı Tanısı ile İzlenen Hastaların İmmünolojik Özelliklerinin Değerlendirilmesi
(Çocuk Sağlığı Enstitüsü, 2024)Childhood Interstitial Lung Diseases (chILD) are a heterogeneous group of chronic respiratory diseases with usually no identifiable etiology. This disease group is rare and exhibits heterogeneous characteristics, showing ... -
İntörn Hekimlerin Tükenmişlik Durumları, Akademik Başarıları, Eğitim Ortamı Algıları ve Öğrenme Yaklaşımlarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2023)In this study we aimed to determine the relation between the burnout status and sosciodemographical factors in the students beginning to the sixth year of education in Zonguldak Bülent Ecevit University School of Medicine ... -
İnvasiv Duktal Meme Karsinoması ile İlişkili Yanlış Anlamlı Mutasyonların Olası Yapısal ve Fonksiyonel Etkilerinin In Silico Tahmini ve Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Invasive Ductal Breast Carcinoma is an important problem in our country as it is in all over the world. For in situ breast cancer patients, the five-year survival rate is 52%, while for metastatic breast cancer patients ... -
İstanbul İli ve Çevresinde Toplanan Kenelerde, Nairo, Flebo ve Flavivirusların Araştırılması
(Sağlık Bilimleri Enstitüsü, 2020)Emanet, N., Investigation of Nairo, Phlebo and Flavivirus in Ticks Collected around Istanbul Province Hacettepe University Graduate School Health Scıences, MSc, thesis in Microbiology, Ankara, 2020. In this study, we ... -
İşyeri Sağlık Personeli Derneği Üyelerinin Çalışma Koşullarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021-02)Oruç, S., Evaluation of the Working Conditions of the Workplace Health Staff Association Members, Hacettepe University Graduate School of Health Sciences Occupational Health Master Thesis, Ankara, 2021. Workplace nurses ... -
İzlem Süresi İçerisinde Belirteçlerin Performanslarını Değerlendirmede Zamana Bağlı Roc Eğrisinin Kullanımı
(Sağlık Bilimleri Enstitüsü, 2015)The ROC (Receiver Operating Characteristic) method commonly used to evaluate the performance of biological markers which often used to help diagnosis and treatment. The performance of the marker should be evaluated with ... -
İzmir İtfaiyesi Çalışanlarının Pandemi Döneminde Meydana Gelen Seferihisar Depreminde COVID-19’un Deprem Yanıtına Etkisi ile İlgili Görüşlerinin ve COVID-19 Korkularının Saptanması
(Sağlık Bilimleri Enstitüsü, 2022)As of 2020, COVID-19, a viral infection, affected the world and caused disease all over the world. On the date (March 11, 2020) it was detected in Turkey, the disease was declared as a pandemic. The response to the ... -
İzole Edilmiş Sıçan Pankreas Adacık Hücrelerine in Vitro Trombospondinin Etkisi
(Sağlık Bilimleri Enstitüsü, 2013)Pancreas islet cells are very sensitive to hypoxic stress because of having small amount of anti-oxidant enzyme. Loss of islet cell viability due to hipoxic damage decreases success of transplantation. Islet- endothelial ...