Browsing Temel Tıp Bilimleri Bölümü Tez Koleksiyonu by Title
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Çocukluk Dönemi Steroide Dirençli Nefrotik Sendroma Sebep Olan Yeni Genlerin Bulunması
(Sağlık Bilimleri Enstitüsü, 2012)Steroid resistant nephrotic syndrome (SRNS), despite being a rare disease, is the second most common cause of end stage kidney failure in childhood and early adulthood. However the heterogeneity and rarity (<1%) of disease ... -
Çok İlaca Dirençli İnvaziv Acinetobacter Baumannii İzolatlarında Biyofilm Yapımının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Multidrug resistant Acinetobacter baumannii isolates lead to epidemics and loss of patients in the hospital setting. In addition to diverse resistance mechanisms, some A. baumannii strains have biofilm producing capacity, ... -
Çok Kategorili Hastalık Durumlarında Tanısal Modele Yeni Bir Belirteç Eklenmesinin Tanı Performansındaki Değişime Etkisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2019-07-23)Accurate assessment of the risks in the field of health, which are derived from diagnostic prediction models is important in identifying patients and healthy people. In some cases, classifications may consist of more ... -
Çoklu Doğrusal Regresyon Çözümlemesinde Farklı Korelasyon Yapılarında %80 Güç İçin Örneklem Büyüklüğünün Belirlenmesi
(Sağlık Bilimleri Enstitüsü, 2019-02-06)Parmaksız, A., Determination of Sample Size for 80% Power in Different Correlation Structures in Multiple Linear Regression Analysis, Hacettepe University Graduate School of Health Scıences Doctor of Philosophy Thesis in ... -
Çoklu Tedavi Etkinliğinin Karşılaştırılmasında Propensıty Skor Ağırlıklandırması
(Sağlık Bilimleri Enstitüsü, 2015-10-14)ABSTRACT Demir, O. Propensity Score Weighting For The Comparison of Multiple Treatment Effects. Hacettepe University, Institute of Sciences, Ph.D. Thesis, Ankara, 2015. In non-randomized quasi-experimental or observational ... -
Çubuk İlçesi’ndeki Devlet Okullarında 2018-2019 Eğitim Öğretim Yılında Öğrenim Gören 4. Sınıf Öğrencilerinde Florürlü Vernik Uygulama Sıklığı ve Ebeveynlerinin Ağız Diş Sağlığı Bilgi ve Uygulamaları
(Sağlık Bilimleri Enstitüsü, 2021-03)Kara M. The Prevalance of Fluoride Varnish Application Among the 4th Grade Students in Public Schools of Çubuk District during 2018-2019 Academic Year and their Parents' Knowledge and Practice Concerning Oral and Dental ... -
Deneysel Hayvan Modelinde Ekstemitelerde Terleme Tedavilerinin Mikroskobik Olarak Değerlendirilmesi
(Tıp Fakültesi, 2020)İsmayilov.T. Microscopic Evaluation of The Treatment of Sweating Therapies In Experimental Animal Model. Hacettepe University, Graduate School of Health Sciences, Ph.D. Thesis in Anatomy, Ankara, 2019. In this study, in ... -
Deneysel Parkinson Hastalığı Modelinde Obezitenin Motor Becerilere Etkisi ve Beyin Tirozin Hidroksilaz Düzeyi, Dopaminerjik Reseptörler ve Leptin Reseptörleri ile İlişkisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023-03)Excessive increase in body weight, which has already become a public health problem, is also associated with many diseases. On the other hand, prolonged life expectancy also increases the incidence of neurodegenerative ... -
Desma Mutant Zebra Balığı Modelinde Tedavi Amaçlı Xmu-Mp-1 Uygulaması
(Sağlık Bilimleri Enstitüsü, 2021)In this thesis, the application of XMU-MP-1 drug candidate molecule which is a MST1 / 2 kinase inhibitor and selectively inhibits the Hippo pathway was performed by mixing the drug with zebrafish embryo egg water or adult ... -
Desma ve Desmb Knockout Zebra Balığı Modellerinde Desmin İfadesinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2017)Desmin, a basic intermediate filament protein specific to muscle tissue, facilitates the transmission of force during muscle contraction and relaxation by forming a large network structure that allows the myofibrils to ... -
Desmin Geni C.1289-2a>G Mutasyonunun Desmin Proteinine Etkisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2012)Autosomal recessive limb girdle muscular dystrophy (LGMD2) is clinically and genetically heterogeneous group of diseases that are characterized by progressive atrophy and weakness of proximal muscles. Two siblings of a ... -
Desmin ve Lamin B Etkileşiminin Zebra Balığında Araştırılması
(Sağlık Bilimleri Enstitüsü, 2017)In this thesis the interaction between desmin, an intermediate filament protein located in cytoplasm and lamin B, intermediate filament protein of the nucleus was investigated using wild type AB zebrafish as a model ... -
Desminin çekirdeğe taşınımının potansiyel mekanizmalarının araştırılması
(Sağlık Bilimleri Enstitüsü, 2024)Kural Mangıt E., Investigation of Potential Mechanisms for Nuclear Transport of Desmin. Hacettepe University, Graduate School of Health Sciences, Ph.D. Thesis in Medical Biology, Ankara, 2024. Studies have shown that ... -
Determination of Lipid Metabolism Alterations and Their Association with Disease Pathogenesis in Sickle Cell Disease
(Sağlık Bilimleri Enstitüsü, 2020-07-07)Sickle cell disease (SCD) is a hemoglobinopathy that causes severe anemia and is characterized by lipid abnormalities, oxidative stress and chronic inflammation. It is caused by a single point-mutation in the beta globin ... -
Development and Application of Novel Machine Learning Approaches for Rna-Seq Data Classification
(Sağlık Bilimleri Enstitüsü, 2015)RNA-Seq is a recent and efficient technique that uses the capabilities of next-generation sequencing technology in characterizing and quantifying transcriptomes. This technique has revolutionized the gene-expression profiling ... -
Diş Hekimliği Öğrencilerinin İletişim Becerileri Eğitimine Yönelik Tutumlarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022-10-11)Communication with patients and their relatives plays a key role for health professionals. It has been reported that effective communication between the patient and the physician increases the patient's satisfaction and ... -
Diyabet Hastalarında Mineral Trioksit Agregat/1α,25-Dihidroksivitamin D3 Kombinasyonu İle Dental Pulpa Kök Hücrelerinde Odontojenik Farklılaşmanın Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021-01-15)Dental treatments in diabetic patients have been reported to fail in the long term and these patients have more tooth extraction. It is aimed to investigate the odonto/osteogenic differentiation potential of the combination ... -
Doğrusal Olmayan Kanonik Korelasyon Analizi ve Türkiye Sağlık Araştırması Verilerine Uygulanması
(Sağlık Bilimleri Enstitüsü, 2023)In this study, it was aimed to examine "Nonlinear Canonical Correlation Analysis (NCCA)", which is defined as a multivariate statistical method that analyzes the relationships between two or more variable sets, including ... -
Doksorubisin Uygulanan Üçlü Negatif Meme Kanserinde Taurinin Tümör Büyüklüğü ve Metastaz Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2023)Gedikli, E., The Effect of Taurine on Tumor Size and Metastasis in Triple Negative Breast Cancer Treated With Doxorubicin, Hacettepe University Graduate School of Health Sciences Physiology Program PhD Thesis, Ankara, 2023. ... -
Doksorubisinin Luminal A ve Üçlü Negatif Meme Kanseri Hücrelerinde p53 Apoptoz Yolağı ve Çoklu İlaç Direnci Üzerinde Farklı Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2017-11-23)Breast cancer is the most common diagnosed cancer type amongst women. Although it is known that cell signaling pathways such as apoptosis, necrosis, and regulation cell cycle are known to be influental on breast cancer ...