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dc.contributor.advisorAydın, Halil Murat
dc.contributor.authorBüyükuysal, Orhan Gökalp
dc.date.accessioned2023-12-12T11:48:21Z
dc.date.issued2023
dc.date.submitted2023-08-25
dc.identifier.urihttps://hdl.handle.net/11655/34285
dc.description.abstractWithin the scope of this master's thesis, conductive and flexible films based on Poly (3,4-ethylene dioxide thiophene):Poly(styrene sulfonate) (PEDOT:PSS) and Poly (3,4-ethylene dioxidethiophene):Heparin (PEHE) were studied. PEDOT:PSS is one of the most successful conductive polymers in the literature. PEDOT:Heparin is one of the promising conductive polymers today. Both offer relatively easy film forming, good conductivity and satisfactory stretchability. PEDOT:PSS and PEDOT:Heparin were synthesized and combined in different proportions using Glycerol and Bis(trifluoromethane) sulfonimide lithium salt as chemical additives. Films were formed by pouring PDMS and PLLA polymers into a mold with a special electronic design printed with a 3D printer. Afterwards, the film channels were coated with conductive polymers by dip coating method and 1.1 mm thick composite films with channels 0.4 mm wide, 62.8 mm long and 0.1 mm deep were obtained. The prepared films were characterized physically, chemically and mechanically, and their cell culture behavior was investigated using the L929 cell line.tr_TR
dc.description.abstractWithin the scope of this master's thesis, conductive and flexible films based on Poly (3,4-ethylene dioxide thiophene):Poly(styrene sulfonate) (PEDOT:PSS) and Poly (3,4-ethylene dioxidethiophene):Heparin (PEHE) were studied. PEDOT:PSS is one of the most successful conductive polymers in the literature. PEDOT:Heparin is one of the promising conductive polymers today. Both offer relatively easy film forming, good conductivity and satisfactory stretchability. PEDOT:PSS and PEDOT:Heparin were synthesized and combined in different proportions using Glycerol and Bis(trifluoromethane) sulfonimide lithium salt as chemical additives. Films were formed by pouring PDMS and PLLA polymers into a mold with a special electronic design printed with a 3D printer. Afterwards, the film channels were coated with conductive polymers by dip coating method and 1.1 mm thick composite films with channels 0.4 mm wide, 62.8 mm long and 0.1 mm deep were obtained. The prepared films were characterized physically, chemically and mechanically, and their cell culture behavior was investigated using the L929 cell line.tr_TR
dc.language.isoturtr_TR
dc.publisherFen Bilimleri Enstitüsütr_TR
dc.rightsinfo:eu-repo/semantics/openAccesstr_TR
dc.subjectSinir Doku Mühendisliğitr_TR
dc.subjectPEDOT:PSStr_TR
dc.subjectPEDOT:Heparintr_TR
dc.subjectPDMStr_TR
dc.subjectİyon değişimitr_TR
dc.subjectİletken ve esnek polimerlertr_TR
dc.subjectLiyofilizasyontr_TR
dc.subjectHücre Kültürütr_TR
dc.subject.lcshMühendisliktr_TR
dc.titleSinir Doku İskelesi Olarak Modifiye Edilmiş Pedot:Pss ve Pedot:Heparin Kaplanmış Kanallar İçeren Pdms Temelli Esnek ve İletken Kompozit Filmlerin Geliştirilmesitr_TR
dc.typeinfo:eu-repo/semantics/masterThesistr_TR
dc.description.ozetBu yüksek lisans tezi kapsamında Poli (3,4-etilen dioksitiyofen):Poli(stiren sülfonat) (PEDOT:PSS) ve Poli (3,4-etilen dioksitiyofen):Heparin (PEHE) temelli iletken ve esnek filmler çalışılmıştır. PEDOT:PSS, literatürde en başarılı olan iletken polimerlerden biridir. PEDOT:Heparin de günümüzde gelecek vaat eden iletken polimerlerdendir. İkisi de görece kolay film oluşturma, iyi iletkenlik ve gerilebilirlik sunmaktadır. PEDOT:PSS ve PEDOT:Heparin sentezlenmiş, kimyasal katkı maddeleri olarak Gliserol ve Bis(triflorometan) sülfonimid lityum tuzu kullanılarak farklı oranlarda birleştirilmiştir. 3B yazıcı ile basılmış özel elektronik tasarıma sahip kalıba PDMS ve PLLA polimerleri dökülerek filmler oluşturulmuştur. Sonrasında film kanalları dip coating yöntemi ile iletken polimerler ile kaplanarak 0,4 mm genişliğinde, 62,8 mm uzunluğunda ve 0,1 mm derinliğinde kanallara sahip 1,1 mm kalınlığındaki kompozit filmler elde edilmiştir. Hazırlanan filmler fiziksel, kimyasal ve mekanik olarak karakterize edilmiş, L929 hücre hattı kullanılarak hücre kültür davranışları incelenmiştir.tr_TR
dc.contributor.departmentBiyomühendisliktr_TR
dc.embargo.termsAcik erisimtr_TR
dc.embargo.lift2023-12-12T11:48:21Z
dc.fundingYoktr_TR


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