Temel Eczacılık Bilimleri Bölümü: Güncel gönderi
Toplam kayıt 192, listelenen: 41-60
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Molecularly Imprinted Biomimetic Surface Plasmon Resonance Sensor For Hormone Detection
(2019)In this study, 17 beta-estradiol (E2) was performed by surface plasmon resonance (SPR) based on molecularly imprinted technique. In the first, SPR sensor was prepared by the formation of E2 imprinted poly(2-hydroxyetyl ... -
Neurotoxic Effects Of Bisphenol A On Sh-Sy5Y Neuroblastoma Cells Via Nitric Oxide
(2019)Bisphenol A (BPA, 2,2-bis(4-hydroxyphenyl)propane)polycarbonate is an industrial component frequently used as an additive in the construction of epoxy resin and other non-polymer plastics. In this study cytotoxicity of low ... -
Low-Dose Bisphenol A Induces Ripk1-Mediated Necroptosis In Sh-Sy5Y Cells: Effects On Tnf-Alpha And Acetylcholinesterase
(2019)Bisphenol A (BPA) is an endocrine disruptor chemical, which is commonly used in everyday products. Adverse effects of its exposure are reported even at picomolar doses. Effects of picomolar and nanomolar concentrations of ... -
Molecularly Imprinted Polymer-Based Microfluidic Systems For Point-Of-Care Applications
(2019)Fast progress has been witnessed in the field of microfluidic systems and allowed outstanding approaches to portable, disposable, low-cost, and easy-to-operate platforms especially for monitoring health status and point-of-care ... -
Kojic Acid Derivatives As Potential Anticancer Agents: Synthesis And Cytotoxic Evaluation On A375 Human Malignant Melanoma Cells
(2019)Malignant melanoma is a serious type of skin cancer with high mortality rates, arising from melanocytic cells responsible for the pigmentation of the skin. Besides, the excessive accumulation of melanin pigment can lead ... -
Analysis Of The Antiproliferative Effect Of Ankaferd Hemostat On Caco-2 Colon Cancer Cells Via Lc/Ms Shotgun Proteomics Approach
(2019)Ankaferd hemostat (ABS), a traditional herbal extract, is a hemostatic agent used for wound healing and bleeding treatment. A standardized form of plants contains many biomolecules. In recent years, previous studies have ... -
Kuzey Kıbrıs Türk Cumhuriyeti’nde Tüketilen Süt Örneklerinde Aflatoksin M1 Düzeylerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)AFM1 is the hydroxylated metabolite of AFB1, and it is formed in the liver by cytochrome P450 enzymes and can be secreted into the urine, feces and milk of mammals. Since AFM1 is a carcinogenic, cytotoxic, teratogenic, ... -
Melaleuca Alternifolia (Çay Ağacı) Yağının Kozmetiklerdeki Güvenliliğinin ve Olası Toksisitesinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Essential oils have been used in cosmetic products for centuries. Its use for many years can be perceived as a reassuring factor; however, some of these oils can be dangerous for consumers through transdermal absorption ... -
Antineoplastik İlaçların DNA ile Etkileşmelerinin UV-Görünür Bölge Spektroskopisi ile İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2020)Atmaca, L., Investigation of Interactions of Antineoplastic Drugs with DNA by UV-Visible Region Spectroscopy, Hacettepe University Graduate School of Health Sciences Department of Analytical Chemistry Master’s Thesis, ... -
The Proline-Rich Tetramerization Peptides In Equine Serum Butyrylcholinesterase
(Wiley-Blackwell, 2012)Soluble, tetrameric, plasma butyrylcholinesterase from horse has previously been shown to include a non-covalently attached polyproline peptide in its structure. The polyproline peptide matched the polyproline-rich region ... -
Yasadışı ve Kötüye Kullanılan Madde Analizlerinin Kapsamı, Kalite ve Güvenlik Gereklilikleri
(Turkiye Sinir Ve Ruh Sagligi Dernegi, 2017)The aim of this review is to inform about the scopes and requirements of drug abuse testing. Drug abuse testing is one of the tools for determination of drug use. It must fulfill the quality and safety requirements in ... -
The Effect of Low-Dose Methotrexate on Autologous Fat Graft Survival
(Tubitak Scientific & Technical Research Council Turkey, 2016)Background/aim: The survival of autologous fat graft tissue is dependent on various factors such as vascularization and inflammation. The aim of the present study was to evaluate the possible beneficial effects of low-dose ... -
Stereological Analysis Of Sciatic Nerve In Chickens Following Neonatal Pinealectomy: An Experimental Study
(2010)Background Although the injury to the peripheral nervous system is a common clinical problem, understanding of the role of melatonin in nerve degeneration and regeneration is incomplete. Methods The current study investigated ... -
Antioxidant and Cytotoxic Effects of Moltkia Aurea Boiss
(Acg Publications, 2012)The water extract of M. aurea exhibited strong scavenging effect on 2,2-diphenyl-1-picrylhydrazil (DPPH), nitric oxide (NO) and superoxide (SO) radicals. The free radical scavenging effect of the extract was found comparable ... -
Surface-Modified Bacterial Nanofibrillar Phb Scaffolds for Bladder Tissue Repair
(Taylor & Francis Ltd, 2016)The aim of the study is in vitro investigation of the feasibility of surface-modified bacterial nanofibrous poly [(R)-3-hydroxybutyrate] (PHB) graft for bladder reconstruction. In this study, the surface of electrospun ... -
Specimen Rejection In Laboratory Medicine: Necessary For Patient Safety?
(2015)Introduction The emergency laboratory in Hacettepe University Hospitals receives specimens from emergency departments (EDs), inpatient services and intensive care units (ICUs). The samples are accepted according to the ... -
Simultaneous Spectrophotometric Determination Of Ezetimibe And Simvastatin In Pharmaceutical Preparations Using Chemometric Techniques
(Soc Brasileira Quimica, 2008)Two spectrophotometric methods are described for the simultaneous determination of ezetimibe (EZE) and simvastatin (SIM) in pharmaceutical preparations. The obtained data was evaluated by using two different chemometric ... -
Solid-Phase Enzyme Modification Via Affinity Chromatography
(Elsevier Science Bv, 2003)In the present study antileukemic enzyme L-asparaginase (ASNase) and catalase (as a model enzyme) were modified in solid-phase with activated polyethylene glycol (PEG,) by using ligand-immobilized affinity column systems ... -
Sensitive Adsorptive Voltammetric Method for Determination of Bisphenol A by Gold Nanoparticle/Polyvinylpyrrolidone-Modified Pencil Graphite Electrode
(2016)A novel electrochemical sensor gold nanoparticle (AuNP)/polyvinylpyrrolidone (PVP) modified pencil graphite electrode (PGE) was developed for the ultrasensitive determination of Bisphenol A (BPA). The gold nanoparticles ...
