Browsing Temel Eczacılık Bilimleri Bölümü by Title
Now showing items 1-20 of 186
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18O-Assisted Dynamic Metabolomics for Individualized Diagnostics and Treatment of Human Diseases
(2012)Technological innovations and translation of basic discoveries to clinical practice drive advances in medicine. Today's innovative technologies enable comprehensive screening of the genome, transcriptome, proteome, and ... -
A Comparison of Hair and Serum Trace Elements in Patients with Alzheimer Disease and Healthy Participants
(Tubitak Scientific & Technical Research Council Turkey, 2015)Background/aim: To determine whether there was a difference between serum and hair trace elements' concentrations in patients with Alzheimer disease (AD) and healthy participants. Materials and methods: Hair and serum ... -
A Method to Determination of Lead Ions In Aqueous Samples: Ultrasound-Assisted Dispersive Liquid-Liquid Microextraction Method Based on Solidification of Floating Organic Drop and Back-Extraction Followed By Faas
(2018)Ultrasound-assisted dispersive liquid-liquid microextraction method based on solidification of floating organic drop and back-extraction (UA-DLLME-SFO-BE) technique was proposed for preconcentration of lead ions. In this ... -
A New Species of Acantholimon Boiss. (Plumbaginaceae) from Ankara, Turkey
(Wiley-Blackwell, 2002)Acantholimon anatolicum Dogan & Akaydin sp. nov. (Plumbaginaceae) is described and illustrated. The species grows on deep gypsum-rich sandy soil on eroded mountain slopes between Cayirhan and Nallihan in Ankara. Diagnostic ... -
Activation and Regioselectivity of Five-Membered Cyclic Thionocarbamates to Nucleophilic Attack
(Royal Soc Chemistry, 2013)The cyclic thionocarbamate of alaninol undergoes nucleophilic attack by sulfur nucleophiles at 5-C to give 1-thiopropyl-2-amine derivatives when derivatised on nitrogen with a Boc group. Iodide under microwave conditions ... -
Akut Miyeloblastik Lösemilerde Gen Temelli Kanser Biyobelirteçlerin Tespiti Aracılığıyla İlaç Duyarlılığı Altgruplarının Belirlenmesi ve Prognoz Ve Tedaviye Cevabın Öngörülmesi
(Sağlık Bilimleri Enstitüsü, 2018-12-18)The aim of this study is to determine the gene-based homogeneous subgroups of acute myeloblastic leukemias using the gene expression profiles of renin angiotensin system, the determination of biomarker potentially genes ... -
Alkole Bağlı Olmayan Karaciğer Yağlanması Tedavisinde Nano-Enkapsüle İlaçların Etkinliğinin Lc/Q-Tof Ms ile Gerçekleştirilen Metabolomik ve Lipidomik Çalışmalarla İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)In this thesis, the efficacy of vitamin E loaded nanoparticles developed using Human Serum Albumin (ISA) nanoparticles in the treatment of non-alcoholic fatty liver disease (NAFLD) was investigated by LC/Q-TOF MS-based ... -
Altered Hdl Particle In Sickle Cell Disease: Decreased Cholesterol Content Is Associated With Hemolysis, Whereas Decreased Apolipoprotein A1 Is Linked To Inflammation
(2019)Background Hypocholesterolemia is the most frequently encountered lipid abnormality in sickle cell disease (SCD). We enrolled pediatric patients to determine the relationships between lipid profile and parameters of ... -
Alzheimer Hastalığı Tedavisinde Kullanılmak Üzere Donepezil Yüklü Plga-B-Peg Nanopartiküllerinin Hazırlanması ve Beyne Hedeflendirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)Alzheimer's disease (AD) is an irreversible and progressive neurodegenerative disease, which is caused by irreversible loss of neurons in the hippocampus and cortex regions of the brain. Although the molecular mechanism ... -
An Artificial Intelligent Diagnostic System on Differential Recognition of Hematopoietic Cells From Microscopic Images
(Wiley-Liss, 1997)Despite their advantages, none of the automated white blood cell differential counters have replaced the conventional microscopic evaluations of blood and bone marrow slides by hematologists, We have analyzed the smears ... -
An Ionic Liquid/Bismuth Film-Modified Sensor For The Electrochemical Detection of Cefixime
(Scientific Technical Research Council Turkey-Tubitak, 2018)A highly sensitive and simple method based on an ionic liquid/ex situ bismuth film-modified single-use pencil graphite electrode (IL/Bi/PGE) was offered for the electrochemical detection of cefixime (CEF) for the first ... -
Analysis Of The Antiproliferative Effect Of Ankaferd Hemostat On Caco-2 Colon Cancer Cells Via Lc/Ms Shotgun Proteomics Approach
(2019)Ankaferd hemostat (ABS), a traditional herbal extract, is a hemostatic agent used for wound healing and bleeding treatment. A standardized form of plants contains many biomolecules. In recent years, previous studies have ... -
Ankaferd Hemostat' In Mcf-7 Meme Kanseri Hücre Hattına Etkisinin Proteomik Analizlerle İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2019)Nowadays, a large number of cancer-related research is being conducted, which is one of the most difficult and deadly diseases to treat. Thanks to one of these studies, proteomics analysis, which is one of the omic techniques, ... -
Anti-Quorum Sensing Potential of Antioxidant Quercetin and Resveratrol
(Inst Tecnologia Parana, 2018)Quorum sensing system plays an active role in the regulation of pathogenicity of many microorganisms. Inhibition of pathogenicity or virulence factors will increase the success of treatment by preventing the development ... -
Antineoplastik İlaçların DNA ile Etkileşmelerinin UV-Görünür Bölge Spektroskopisi ile İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2020)Atmaca, L., Investigation of Interactions of Antineoplastic Drugs with DNA by UV-Visible Region Spectroscopy, Hacettepe University Graduate School of Health Sciences Department of Analytical Chemistry Master’s Thesis, ... -
Antioxidant and Cytotoxic Effects of Moltkia Aurea Boiss
(Acg Publications, 2012)The water extract of M. aurea exhibited strong scavenging effect on 2,2-diphenyl-1-picrylhydrazil (DPPH), nitric oxide (NO) and superoxide (SO) radicals. The free radical scavenging effect of the extract was found comparable ... -
Antioxidant Sme1Ec2 Modulates Pentose Phosphate Pathway and Glutathione-Dependent Enzyme Activities in Tissues of Aged Diabetic Rats
(2017)The pentose phosphate pathway and glutathione-associated metabolism are the main antioxidant cellular defense systems. This study investigated the effects of the powerful antioxidant SMe1EC2 (2-ethoxycarbonyl-8-methoxy-2 ... -
Antiviral Properties Of Caffeic Acid Phenethyl Ester And Its Potential Application
(2015)Caffeic acid phenethyl ester (CAPE) is found in a variety of plants and well-known the active ingredient of the honeybee propolis. CAPE showed anti-inflammatory, anticarcinogenic, antimitogenic, antiviral, and immunomodulatory ...
