Yazar "Mender, İlgen" için Temel Eczacılık Bilimleri Bölümü listeleme
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Induction Of Telomere Dysfunction Mediated By The Telomerase Substrate Precursor 6-Thio-2'-Deoxyguanosine
Mender, Ilgen; Gryaznov, Sergei; Dikmen, Z. Gunnur; Wright, Woodring E.; Shay, Jerry W. (Amer Assoc Cancer Research, 2015)The relationships between telomerase and telomeres represent attractive targets for new anticancer agents. Here, we report that the nucleoside analogue 6-thio-2'-deoxyguanosine (6-thio-dG) is recognized by telomerase and ...