Eczacılık Teknolojisi Bölümü: Güncel gönderi
Toplam kayıt 95, listelenen: 21-40
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Böbrek Görüntüleme Amacıyla Kullanılan Teknesyum-99m (Tc-99m) ve Galyum-68 (Ga-68) İşaretli Radyofarmasötiklerin Etkinliklerinin Karşılaştırılması
(Sağlık Bilimleri Enstitüsü, 2022-03-25)PET and SPECT has an obvious diagnostic advantage over anatomical techniques such as classical BT and MR in determining biochemical changes which mainly occurs before anatomical changes. Most powerful sides of PET are ... -
Galyum-68 (Ga-68) İşaretli, Nanoboyutlu, Peg Kaplı, Tümöre Hedeflendirilmiş, Lipozomlar Kullanılarak Tümör Görüntülenmesi Üzerine Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2022-02-15)Diagnosis of the tumor before the cellular changes begin and when changes begin to occur at the molecular level ensures that the treatment is started before the cancer spreads, thus increasing the success rate in the ... -
Çözünürlüğü ve Çözünme Hızı Artırılmış Selekoksib Formülasyonlarının Tasarımı, Optimizasyonu ve İn Vitro/İn Vivo Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Dry co-milling is a technology that has been widely used in recent years and can be applied in the pharmaceutical industry to improve the solubility and dissolution rate of poorly soluble active substances. Quality by ... -
Mycobacterium bovis Antijenlerinin Escherichia coli’de Rekombinant DNA Teknolojisi ile Üretimi ve Alt Birim Aşı Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Duzenli, O.F., Production of Mycobacterium bovis Antigens in Escherichia coli by Recombinant DNA Technology and Subunit Vaccine Development, Hacettepe University Graduate School of Health Sciences Pharmaceutical ... -
Effect Of Particle Size And Surfactant On The Solubility, Permeability And Dissolution Characteristics Of Deferasirox
(2019)Deferasirox is an oral iron chelator used for the treatment of chronic iron overload in blood transfusions. Deferasirox is a BCS Class II drug with low solubility and high permeability. In the formulation development stage ... -
Determination Of N-Acetylcysteine In The Presence Of Ciprofloxacin Or Levofloxacin In Microparticulate Dry Powder Inhalers
(2019)A fast and easy method was validated for simultaneous determination of ciprofloxacin hydrochloride mono hydrate (CP), levofloxacin hemihydrate (LV), and N-acetylcysteine (NAC) in samples. The analysis was performed on a ... -
Development Of Dry Powder Inhaler Formulations For Drug Delivery Systems
(2019)Oral or parenteral administration of drugs to treat lung diseases is met with several challenges, including delivery of the active substance in insufficient amounts, inability to produce the desired effect at the target ... -
DİYABETİK MAKÜLER ÖDEM TEDAVİSİNDE NANOPARTİKÜLER KARBONİK ANHİDRAZ İNHİBİTÖR ETKİNLİĞİNİN DEĞERLENDİRİLMESİ
(Sağlık Bilimleri Enstitüsü, 2021-05-17)Diabetic Retinopathy (DRP) is a clinical picture formed by all structural and functional changes in the retinal layer of the eye due to diabetes. Intravitreal injections are the gold standard treatment option for DRP, ... -
Diyabetik Maküler Ödem Tedavisinde Nanopartiküler Karbonik Anhidraz İnhibitör Etkinliğinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021-05-17)Diabetic Retinopathy (DRP) is a clinical picture formed by all structural and functional changes in the retinal layer of the eye due to diabetes. Intravitreal injections are the gold standard treatment option for DRP, ... -
Karaciğerdeki İlaç Dispozisyonu Üzerine Rifampisinin Etkisinin İncelenmesi ve Farmakokinetik Modelleme
(Sağlık Bilimleri Enstitüsü, 2020)Transporter-mediated pharmacokinetics is one of the determinants in hepatic drug disposition and drug-drug interactions. Among several influx (uptake) transporters expressed in the membranes of hepatocytes, hepatic organic ... -
Beyı̇ne Hedeflendı̇rı̇Lmı̇Ş Bevası̇ Zumab YüKlü Nanopartı̇KüLer İLaç TaşIyıcı Sı̇Stemlerı̇N Hazırlanması Ve Etkı̇nlı̇Klerı̇nin Değerlendı̇rı̇Lmesı̇
(Sağlık Bilimleri Enstitüsü, 2020)In this study, in order to target Bevacizumab to the brain, PLGA-PEG nanoparticles conjugated with Anti-CD71 antibodies that bind specifically to transferrin receptors known to be expressed in the blood-brain endothelium ... -
Polisorbat 80 Kaplı, Kurkumin Ve Dosetaksel Yüklü Plga Nanopartiküler Sistemlerin Geliştirilmesi ve Beyin Tümörü Etkinliklerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020)Seko, I. Synthesis, evaluation of in vitro and in vivo activities of curcumin and docetaxel loaded polysorbate 80 coated PLGA nanoparticulate systems. Hacettepe University Graduate School Health Sciences Institute, ... -
Bakteriyel Keratit Tedavisine Yönelik Besifloksasin Yüklü Oküler İnsertlerin Elektro-Eğirme Yöntemi ile Geliştirilmesi ve Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020-08-12)Polat, H.K. Development and Evaluation of Besifloxacin HCl Loaded Ocular Inserts by Electro-Spinning Method for Bacterial Keratitis Treatment, Hacettepe University Graduate School of Health Sciences, Pharmaceutical Technology ... -
Keratokonus Tedavisinde Riboflavin’in Girişimsel Olmayan (“Epi-On”) Teknik ile Korneaya Taşınması İçin Oküler İlaç Taşıyıcı Platformların Tasarlanması ve İn Vitro-İn Vivo Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020-08-13)Aytekin E. Design and In vitro - In vivo Evaluation of Ocular Drug Delivery Platforms for the Delivery of Riboflavin by Noninvasive (“Epi-On”) Technique in the Treatment of Keratoconus, Hacettepe University Graduate School ... -
Spect Radyofarmasötiklerinden 201tlcl’ün Üretimi ve Kalite Kontrolü
(Sağlık Bilimleri Enstitüsü, 2020)In this study, industrial production of 201Tl radioisotope, which is produced for the first time in Turkey, and development of quality control tests of synthesized 201TlCl radiopharmaceutical, research on its test methods ... -
Kolorektal Kanserlerin Lokal Tedavisinde Oral Uygulanabilen Nanopartiküler İlaç Taşıyıcı Sistem Geliştirilmesi ve İn Vitro/İn Vivo Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020)Anticancer drugs need to be administered via the parenteral route because of limitations arising from their physicochemical properties. Non-specific biodistribution and difficulty in parenteral administration adversely ... -
Determination Of Regional Intestinal Permeability Of Diclofenac And Metoprolol Using A Newly-Developed And Validated High Performance Liquid Chromatographic Method
(Pharmacotherapy Group, 2015)Purpose: To develop a simple and rapid reversed-phase high performance liquid chromatographic (HPLC) method with UV detection for the simultaneous determination of diclofenac, metoprolol tartrate, phenol red and propyl ... -
Design And Characterization Of Nanocrystal Formulations Containing Ezetimibe
(Pharmaceutical Soc Japan, 2011)Ezetimibe is a lipid-lowering compound that selectively inhibits the absorption of cholesterol and related phytosterols from the intestine As ezetimibe is almost Insoluble in water, its bioavailability is too low to be ... -
Dendrimeric Systems And Their Applications In Ocular Drug Delivery
(2013)Ophthalmic drug delivery is one of the most attractive and challenging research area for pharmaceutical scientists and ophthalmologists. Absorption of an ophthalmic drug in conventional dosage forms is seriously limited ...
