Başlık için Eczacılık Teknolojisi Bölümü listeleme
Toplam kayıt 95, listelenen: 1-20
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18Th European Symposium On Radiopharmacy And Radiopharmaceuticals
(2016)OP03 Selective extraction of medically-related radionuclides from proton-irradiated thorium targets, V. Radchenko, J.W. Engle, C. Roy, J. Griswold, M.F. Nortier, E.R. Birnbaum, M. Brugh, S. Mirzadeh, K. D. John, M.E. ... -
A Quadruped Study on Chitosan Microspheres Containing Atorvastatin Calcium: Preparation, Characterization, Quantification And In-Vivo Application
(Pharmaceutical Soc Japan, 2010)Atorvastatin is commonly used as a cholesterol lowering agent in patients. Recently, the neuroprotective effects of atorvastatin became the focus of many research studies. In this study, we have formulated chitosan ... -
Ağızda Dağılan Tablet Formülasyonlarının In Vitro Karakterizasyonları ve Permeabiliteleri Üzerine Farklı Yardımcı Maddelerin ve Basım Tekniklerinin Etkisi
(Sağlık Bilimleri Enstitüsü, 2019)Orally disintegrating tablets are easier and safer to administered in pediatric and geriatrics, patients with difficulty in swallowing and neurological diseases compared with conventional tablets. Orally disintegrating ... -
Akciğer Kanseri Tedavisinde Kullanılmak Üzere Nanopartikül İçeren Kuru Toz İnhalerformülasyonu Hazırlanması, Karakterizasyonu ve İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2023)In this thesis, the aim was to develop a dry powder inhaler formulation containing gefitinib nanoparticles for the treatment of non-small cell lung cancer. Gefitinib nanoparticles, below 130 nm in size, were prepared using ... -
Akciğer Kanserine Yönelik siRNA Taşıyıcı Polimerik Nanopartiküllerin Geliştirilmesi ve Etkinliklerinin İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022). Lung cancer, one of the most common type of cancers, has the highest mortality rate among all types of cancer, The low effectiveness of current therapies and serious side and toxic effects lead researchers to develop ... -
Akut Omurilik Travmalarında Kullanılmak Üzere Nöroprotektif İlaç Yüklü Nanopartiküler İlaç Taşıyıcı Sistem Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)Methyl prednisolone sodium succinate (MPSS) is a very hydrophilic synthetic glucocorticoid. Although it is usually used for its antiinflammatory effects, it is still the only efficacy proven therapeutic agent which is ... -
An Overview on Dry Eye Treatment: Approaches for Cyclosporin A Delivery
(2012)Dry eye syndrome (DES, Keratoconjunctivitis sicca) is a common disorder of the tear film caused by decreased tear production or increased evaporation. Changes in tear composition also promote inflammation on the ocular ... -
Antibiyotik İçeren Kuru Toz İnhaler Formülasyonu Tasarımı ve Permeabilite Çalışmaları
(Sağlık Bilimleri Enstitüsü, 2017)The aim of this thesis is to develope dry powder inhaler formulation with antibiotic and mucolytic combination to use in the treatment of the lung infection in cystic fibrosis disease. For this purpose, in this thesis, ... -
Antiparaziter İlaçlar Yüklü Hedeflendirilmiş Nanotaşıyıcıların Formülasyonu ve Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2024-05-17)Gültekin, Y., Formulation and Evaluation of Targeted Nanocarriers Loaded with Antiparasitic Drugs, Hacettepe University Graduate School of Health Sciences, Pharmaceutical Technology Program, Ph.D Thesis, Ankara, 2024. ... -
Bakteriyel Keratit Tedavisine Yönelik Besifloksasin Yüklü Oküler İnsertlerin Elektro-Eğirme Yöntemi ile Geliştirilmesi ve Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020-08-12)Polat, H.K. Development and Evaluation of Besifloxacin HCl Loaded Ocular Inserts by Electro-Spinning Method for Bacterial Keratitis Treatment, Hacettepe University Graduate School of Health Sciences, Pharmaceutical Technology ... -
Barsaklardan Paraselüler Ilaç Absorpsiyonu Üzerine Permeabilite Artırıcı Ajanların Etkisinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2013)The aim of this study was to investigate the effect of permeability enhancers on paracellular drug absorption. For this purpose, acyclovir classified as Class III drug (high solubility and low permeability) according to ... -
Beyı̇ne Hedeflendı̇rı̇Lmı̇Ş Bevası̇ Zumab YüKlü Nanopartı̇KüLer İLaç TaşIyıcı Sı̇Stemlerı̇N Hazırlanması Ve Etkı̇nlı̇Klerı̇nin Değerlendı̇rı̇Lmesı̇
(Sağlık Bilimleri Enstitüsü, 2020)In this study, in order to target Bevacizumab to the brain, PLGA-PEG nanoparticles conjugated with Anti-CD71 antibodies that bind specifically to transferrin receptors known to be expressed in the blood-brain endothelium ... -
Böbrek Görüntüleme Amacıyla Kullanılan Teknesyum-99m (Tc-99m) ve Galyum-68 (Ga-68) İşaretli Radyofarmasötiklerin Etkinliklerinin Karşılaştırılması
(Sağlık Bilimleri Enstitüsü, 2022-03-25)PET and SPECT has an obvious diagnostic advantage over anatomical techniques such as classical BT and MR in determining biochemical changes which mainly occurs before anatomical changes. Most powerful sides of PET are ... -
Characterization Of Protein And Peptide Binding To Nanogels Formed By Differently Charged Chitosan Derivatives
(2013)Chitosan (Chi) is a natural biodegradable cationic polymer with remarkable potency as a vehicle for drug or vaccine delivery. Chi possesses multiple groups, which can be used both for Chi derivatization and for particle ... -
Comparison Of Dissolution Profiles Of Commercially Available Lamivudine Tablets
(Dissolution Technologies, Inc, 2015)The aim of this study was to investigate the influence of dissolution medium on the in vitro release of lamivudine (100 mg) from four commercially available lamivudine tablets (one reference and three generic). Three ... -
Çözünürlüğü ve Çözünme Hızı Artırılmış Selekoksib Formülasyonlarının Tasarımı, Optimizasyonu ve İn Vitro/İn Vivo Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Dry co-milling is a technology that has been widely used in recent years and can be applied in the pharmaceutical industry to improve the solubility and dissolution rate of poorly soluble active substances. Quality by ... -
Dendrimeric Systems And Their Applications In Ocular Drug Delivery
(2013)Ophthalmic drug delivery is one of the most attractive and challenging research area for pharmaceutical scientists and ophthalmologists. Absorption of an ophthalmic drug in conventional dosage forms is seriously limited ... -
Design And Characterization Of Nanocrystal Formulations Containing Ezetimibe
(Pharmaceutical Soc Japan, 2011)Ezetimibe is a lipid-lowering compound that selectively inhibits the absorption of cholesterol and related phytosterols from the intestine As ezetimibe is almost Insoluble in water, its bioavailability is too low to be ... -
Determination Of N-Acetylcysteine In The Presence Of Ciprofloxacin Or Levofloxacin In Microparticulate Dry Powder Inhalers
(2019)A fast and easy method was validated for simultaneous determination of ciprofloxacin hydrochloride mono hydrate (CP), levofloxacin hemihydrate (LV), and N-acetylcysteine (NAC) in samples. The analysis was performed on a ...