Başlık için Eczacılık Meslek Bilimleri Bölümü listeleme
Toplam kayıt 336, listelenen: 45-64
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Bazı 2-(4-Sübstitüe)Fenil-5-Benziliden P-Sübstitüebenziliden-3-Fenilaminotiyazolidin-4-On Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2014)In this study, 2 new compunds having 3- (phenylamino)-2-[4-(1H-1,2,4-triazole/imidazolyl)phenyl]-1,3-thiazolidin-4-one (Compounds 1,2) and 9 new compounds having 5-(benzylidene/-psubstitutedbenzylidene)- 3-(phenylamin ... -
Bazı 2-Sübstitüe-1H-Benzimidazol Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2019)In this study, 12 (1 of registered in the literature) 2-(1H-benzo[d]imidazol-2-yl)-3-(4-(4-substitutedpiperazin-1- yl)phenyl)acrylonitrile (3a-l) and 3 2-(1H-benzo[d]imidazol-2-yl)-3-(4-(4- substitutedpiperazin-1-yl)p ... -
Bazı 2-Sübstitüe-4-(Furan-2-İlmetil)-6-MetilPiridazin-3(2H)-on Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2021-07-08)In this study, 16 new compounds, 2-[5-(furan-2-ylmethyl)-3-methyl-6-oxopyridazin-1(6H)-yl]-N-(aryl)acetamide (5a-j) and 4-(furan-2-ylmethyl)-6-methyl-2-[2-oxo-2-(4-arylpiperazin-1-yl)ethyl]pyridazin-3(2H)-one (6a-f), which ... -
Bazı 5-Kloro-2-benzoksazolinon Tiyosemikarbazit, 1,3,4-Tiyadiazol ve 1,2,4-Triazol-5-tiyon Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2018)In this study, nineteen new compounds which have 1-[2-(5-chloro-2-benzoxazolinone-3-yl)acetyl]-4-substitutedthiosemicarbazide, 3-[(5-chloro-2-benzoxazolinone-3-yl)methyl]-4-substituted-1H-1,2,4-triazole-5(4H)-thione, ... -
Bazı Benzotiyazol Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2018)In this study, fifteen 2-(4-substitutedphenyl)benzo[d]thiazole derivatives carrying substituted piperazine and azole moities at the 4 position of phenyl ring were synthesized, of which two had been reported in literature ... -
Bazı Gentiana Türleri Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2013)The genus Gentiana (Gentianaceae) consists species with important phytochemical properties and have been widely used in traditional folk medicine. Iridoids, secoiridoids, C-glycosylflavones and xanthones are considered ... -
Bazı Gentianella Türlerinin Fitokimyasal Analizleri ve Sekonder Metabolitlerinin BDNF (Beyin-Türevli Nörotrofik Faktör) Üzerindeki Etkileri
(Sağlık Bilimleri Enstitüsü, 2022)Gentianella Moench (Gentianaceae) species contain many secondary metabolites such as xanthones, flavonoids and terpenes. Flavonoids have been reported to contribute to the antidepressant effects of many medicinal plants ... -
Bazı Lamiaceae Familyası Bitkilerinin Osteoartrite Karşı Etkilerinin Matriks Metalloproteinaz-3 (Mmp-3) İnhibitör Etki Tayini ile Tespiti
(Sağlık Bilimleri Enstitüsü, 2021)Tahravi, L., Characterization of the Effects of Some Lamiaceae Family Plants Against Osteoarthritis by Matrix Metalloproteinase-3 (MMP-3) Inhibitory Effect Determination, Hacettepe University, Graduate School of Health ... -
Bazı N-(4-Sübstitüebenziliden)-5-Fenil-1,3,4-Tiyadiazol-2-Amin Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2018)In this study, 9 new compounds having 2-substituted-5-phenyl-1,3,4-thiadiazole structures were synthesized and their antifungal and antibacterial activities were evaluated. Target compounds were synthesized by reaction of ... -
Bazı Yeni 2-Pirazolin Türevlerinin Sentezi ve Monoamin Oksidaz (Mao) İnhibitör Aktiviteleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2015)In this study, forty two compounds which have 1-[2-(5-substituted-2- benzoxazolinone-3-yl)acetyl]-3,5-disubstitutedphenyl-4,5-dihydro-1H-pyrazole structure and nine compounds which have N’-(1,3-disubstitutedphenylallyl ... -
Bazı Yeni Tiyazolo[3,2-b]-1,2,4-triazol-6(5H)-on Türevlerinin Sentezi ve Sitotoksik Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021-07-13)In this study, thirty new hybrid chalcone derivatives, namely 2- substituted-5-benzylidentiazolo[3,2-b]-1,2,4-triazol-6(5H)-one (4a-6j) which is expected to show cytotoxic activity were synthesized. Titled compounds were ... -
Benzoksazolinon-hidrazon farmakoforu taşıyan dual etkili mao-aromataz inhibitörlerinin tasarımı ve sentezi: in siliko ve in vitro çalışmalar
(Sağlık Bilimleri Enstitüsü, 2022)Taşçi, N., Design and synthesis of dual MAO-Aromatase inhibitors containing benzoxazolinone-hydrazone pharmacophore: In silico and in vitro studies, Hacettepe University, Graduate School of Health Sciences PhD Thesis in ... -
Bioactivity-Guided Isolation Of Anti-Inflammatory Principles From Cistus Parviflorus Lam.
(2019)Bioactivity-guided fractionation and purification of Cistus parvillorus led to the isolation of two flavan-3-ol derivatives; gallocatechin (1) and epigallocatechin (2) and two flavonoid glycosides; avicularin (3) and ... -
Bisfenol Türevlerinin Oksidatif Stres Parametreleri Üzerine Etkilerinin HepG2 Hücrelerinde Karşılaştırmalı Olarak Değerlendirilmesi.
(Sağlık Bilimleri Enstitüsü, 2018)Bisphenols belong to a chemical group known as diphenylmethanes and widely used in the production of polycarbonate plastics, as basic chemicals in the resin coating of food and beverage tins. These substances are suggested ... -
Bitkisel Kaynaklı Fenolik Yapıdaki Bileşiklerin Olası Sitotoksik ve Genotoksik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2014)Free oxygen radicals react with genetic material such as DNA, RNA and other cell macromolecules and the cause oxidative damage. There is a worldwide increasing interest about antioxidant compounds which could delay or ... -
Bmprii Deficiency Impairs Apoptosis Via The Bmprii-Alk1-Bclx-Mediated Pathway In Pulmonary Arterial Hypertension
(2019)Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder characterized by the remodelling of pre-capillary pulmonary arteries. The vascular remodelling observed in PAH patients results from excessive ... -
Capecitabine Induced Hand-Foot Syndrome: A Systematic Review Of Case Reports
(2019)Objective: Capecitabine, a prodrug of 5-fluorouracil, is currently used in the treatment of metastatic colorectal and breast cancers. The aim of this study was to review the pharmacological mechanisms, treatment strategies, ... -
Cardenolide Production As An Important Drug Agent
(Bentham Science Publ, 2012)Leaves of Digitalis plants are still the major source for the isolation of cardenolides, especially digitoxin and digoxin that are used to treat cardiac insufficiency in humans. Cardenolides are characterized by a steroid ...