Başlık için Eczacılık Meslek Bilimleri Bölümü listeleme
Toplam kayıt 341, listelenen: 180-199
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Kardiyak Cerrahi Hastalarında Preoperatif ve Postoperatif Dönemde Risk Analizi ile İlaç Tedavisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023)This study aimed to identify drug related problems (DRPs), analyze the risks and evaluate the impact of a clinical pharmacist in risk management process of cardiac surgery. Prospective, quasi-experimental study was conducted ... -
Kardiyovasküler Toksisite Olasılığı Bulunan Bazı İlaçlar Ile Zehirlenmelerin Beyin Natriüretik Peptid Düzeyi Ile Ilişkisi
(Sağlık Bilimleri Enstitüsü, 2014)Nowadays, referrals to emergency departments due to intoxication remains to be important in terms of mortality and morbidity. Among these intoxications, cases with cardiac involvement should be closely monitored. ... -
Kaynak İşçilerinde Mesleki Maruziyete Bağlı Olası Oksidatif Stres Göstergelerindeki Değişikliklerin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2018-07-05)In recent years, the welding, which is an easier and faster technique than the mechanical methods in cutting and joining metals, is widely used by the manufacturers and repairers. The main potential hazards in welding are; ... -
Kaynak İşçilerinde Mesleki Maruziyete Bağlı Olası Toksik Etkilerin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-07-27)Aksu, İ., Evaluation of Possible Genotoxic Damage in Welders Due to Occupational Exposure, Hacettepe University Institute of Health Sciences, Ph.D. Thesis in Pharmaceutical Toxicology, Ankara, 2018. Welding is widely applied ... -
Kojik Asit Türevi Bileşiklerin Tasarımı, Sentezi ve Melanoma Hücresine Karşı Sitotoksisiteleri ile Tirozinaz İnhibisyonu Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)Tyrosinase is an enzyme that acts as a catalyst in the biosynthesis of melanin pigment, which is found in fungi, in plants and in animals. Overproduction and accumulation of this pigment causes hyperpigmentation, post ... -
Kojik Asit Türevi Mannich Bazlarının Sentezi ve İnsan Melanoma Hücrelerine Etkisi ile Antitirozinaz Aktivitelerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2017)Malign melanoma is malign tumour of melanin pigment, which gives colour of skin, eyes and hair. It has an increasing rate of incidence and high mortality. Tyrosinase is the enzyme responsible for melanin production in ... -
Kondanse 1,4-Dihidropiridin Türevlerinin Sentezi ile Antimikrobiyal ve Antioksidan Etkileri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2019)BAYDAR, E. The Studies on Synthesis of Condensed 1,4-Dihydropyridine Derivatives and Their Antimicrobial and Antioxidant activities, Hacettepe University, Graduate School of Health Sciences, Master Thesis in Pharmaceutical ... -
Kondanse 1,4-Dihidropiridin Türevlerinin Sentezi ve L-/T-Tipi Kalsiyum Kanalları Üzerine Etkileri
(Sağlık Bilimleri Enstitüsü, 2019)1,4-Dihydropyridines (DHPs) are crucial blockers of different calcium channel subtypes and have great therapeutic value against cardiovascular and neurophysiologic conditions. In this thesis, the design and the synthesis ... -
Kondanse 1,4-Dihidropiridin-3-Karboksilat Türevleri ve Kalsiyum Modülatör Etkileri
(Sağlık Bilimleri Enstitüsü, 2015)In this study sixteen 2,6,6-trimethyl-4-aryl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (compound 1-16) have been synthesized. The synthesis of the compounds was realised by the reaction of the 4,4-dimethyl-1,3-c ... -
Kök Hücrelerde Olası DNA Hasarı ve Onarımının İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2016-12-26)Stem cells provide an opportunity to analyse the effects of xenobiotic on cell viability, differentiation and cell functions. For this reason, it is suitable alternative for in vitro and in vivo methods. Evaluation of the ... -
Kronik Levetirasetam Uygulanan Normal ve Temporal Lob Epilepsi Modeli Oluşturulmuş Sıçanlarda Aromataz Ekspresyonu Değişiklikleri
(Sağlık Bilimleri Enstitüsü, 2015)Temporal lobe epilepsy (TLE) model was generated at male Wistar rats by intraperitoneal (i.p.) injection of excitotoxic agent kainic acid (KA). This thesis work has been done as to investigate possible side-effects on ... -
Kurşun Maruziyeti ve Şelasyon Tedavisi Sonrası Metabolomik ve Lipidomik Analizler
(Sağlık Bilimleri Enstitüsü, 2021)Lead is a widely preferred heavy metal in the industry due to its useful physicochemical properties and it has important toxic effects. Chelation agents are used in its treatment and intravenous sodium calcium edta is one ... -
Lavandula stoechas L. subsp. stoechas Üzerinde Biyolojik Aktivite Rehberli Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2023)Lavandula stoechas L. subsp. stoechas known as “karabaş otu” is used for diabetes and central nervous system disorders. This thesis focuses on scientifically validating the traditional usage of L. stoechas subsp. stoechas ... -
Leadership and Healthcare Services
(Intech Europe, 2017)The reasons why organizations make changes in various fields, especially in their structure, include various changing situations such as globalization, increasing awareness in human rights and employee rights, developments ... -
Low Dose Simvastatin Induces Compositional, Structural and Dynamic Changes in Rat Skeletal Extensor Digitorum Longus Muscle Tissue
(Portland Press Ltd, 2010)Statins are commonly used drugs in the treatment of hypercholesterolaemia. There are many adverse effects of statins on skeletal muscle, but the underlying mechanisms remain unclear. In the present study, the effects of ... -
Low Doses Of Selenium Specifically Stimulate The Repair Of Oxidative Dna Damage In Lncap Prostate Cancer Cells
(Informa Healthcare, 2012)Epidemiological studies have demonstrated an inverse relationship between selenium (Se) intake and cancer incidence and/or mortality. However, the molecular mechanisms underlying the cancer chemopreventive activity of Se ... -
Luddin Type Anthraquinone Glycosides from Putoria Calabrica
(Pharmaceutical Soc Japan, 2002)Two new lucidin type anthraquinone glycosides, putorinoside A (1) and putorinoside B (2) were isolated from Putoria calabrica, in addition to two known anthraquinone glycosides, lucidin 3-O-beta-glucopyranoside (3) and ... -
Lycopene Restores Trace Element Levels in Ochratoxin A-Treated Rats
(Inst Medical Research & Occupational Health, 2017)This study was designed to investigate the in vivo effects of ochratoxin A (OTA) and/or lycopene on the levels of selenium, zinc, and copper in the liver, kidneys, and testes of male Sprague-Dawley rats. The rats were ...