Başlık için Eczacılık Meslek Bilimleri Bölümü listeleme
Toplam kayıt 337, listelenen: 86-105
-
Design, Synthesis And In Vivo/In Vitro Screening Of Novel Chlorokojic Acid Derivatives
(Taylor & Francis Ltd, 2013)A series of novel Mannich bases of chlorokojic acid (2-chloromethyl-5-hydroxy-4H-pyran-4-one) were synthesized and their biological activities were investigated. Anticonvulsant activity results according to phase-I tests ... -
Detection Of Neopterin In Tear Samples
(Walter De Gruyter Gmbh, 2016)The main goal of the present study was to detect neopterin concentrations in human tear samples and to evaluate its potential correlation with serum neopterin levels. For this purpose, 20 systemically healthy volunteers ... -
Dibutil Ftalatın İnsan Akciğer Hücre Hattına Toksik Etkilerinin Değerlendirilmesi ve Askorbik Asit ve N-Asetilsisteinin Olası Koruyucu Etkileri
(Sağlık Bilimleri Enstitüsü, 2020)Endocrine disruptings are chemical substances which are generally produced by humans that disrupt the normal functioning of the body by imitating or blocking hormones. The mostly studied phthalate derivative is ... -
Dihidropiridin Türevlerinin Sentezi ve L-/T-Tipi Kalsiyum Kanal Bloke Edici Aktiviteleri
(Sağlık Bilimleri Enstitüsü, 2022-07-19)1,4- Dihydropyridines (DHPs) are the most well known inhibitors of L-type calcium channels and have important therapeutic value against cardiovascular diseases. Since they target different calcium channel subtypes, they ... -
Dinitroanilin Herbisitlerin Neden Olduğu Genotoksik Etkilerin ve Epigenetik Değişikliklerin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)It has been shown that genetic damage has an improtant role in the mechanisms of cancer and other chronic diseases that have been observed all over the world. Recently, theory about that epigenetic changes are also responsible ... -
Direct Enantiomeric Resolution Of Seventeen Racemic 1,4-Dihydropyridine-Based Hexahydroquinoline Derivatives By Hplc
(2019)1,4-Dihydropyridine (DHP) scaffold holds an outstanding position with its versatile pharmacological properties among all heterocyclic compounds. Although most of the commercially available DHPs are marketed as a racemic ... -
Discovery And Characterisation Of Dual Inhibitors Of Tryptophan 2,3-Dioxygenase (Tdo2) And Indoleamine 2,3-Dioxygenase 1 (Ido1) Using Virtual Screening
(2019)Cancers express tryptophan catabolising enzymes indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO2) to produce immunosuppressive tryptophan metabolites that undermine patients’ immune systems, leading ... -
Diyabet Hastalarında Pteridinlerin ve İlgili Yolakların Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-07-04)Gurcu, S., Evaluation of Pteridins and Related Pathways in Diabetes, Hacettepe University Institute of Health Sciences Ph.D. Thesis in Pharmaceutical Toxicology, Ankara, 2018. Pteridins are heterocyclic compounds that play ... -
Eczacılık Fakültesi Laboratuvar Çalışma Güvenliği El Kitabı
(Hacettepe Üniversitesi Yayınları, 2017)30.06.2012 tarihinden itibaren uygulamaya ilişkin çok sayıda yönetmelik ve tebliğ yayımlanmıştır. Bunlardan biri olan "Çalışanların İSG Eğitimlerinin Usul ve Esasları Hakkında Yönetmelik" gereğince, "az tehlikeli işyerleri" ... -
Eczane İçi Etkileşimlerin Konuşma Çözümlemesi Yoluyla İncelenmesi: Uzmanlık Bilgisi Gösterimi
(Sağlık Bilimleri Enstitüsü, 2018)Pharmaceutical care is defined as practitioner responsibility that optimizes the patient to use drug treatment as effectively and safely as possible under all circumstances. The importance of communication skills for ... -
Effects Of Cinnamic Acid On Complications Of Diabetes
(Tubitak Scientific & Technical Research Council Turkey, 2018)Background/aim: Diabetes mellitus (DM) is a major health problem worldwide. Cinnamic acid (CA) and its derivatives are synthesized in plants and increasing attention has been given to them in recent years due to the high ... -
Effects Of Developmental Exposure To Silver In Ionic And Nanoparticle Form: A Study In Rats
(2016)Background Evaluations of silver in both nanoparticle (Ag-NPs) and ionic forms indicate some adverse effects on living organisms, but little is known about their potential for developmental toxicity. In this study, ... -
ELAZIĞ BÖLGESİ SİYAH ÜZÜMÜNÜN (VİTİS VİNİFERA L.) ENDÜSTRİYEL ATIKLARINDAN YÜKSEK SAFLIKTA RESVERATROL ELDE EDİLMESİ
(Sağlık Bilimleri Enstitüsü, 2024)Akcan, A.Y., Obtaining High Purity Resveratrol from Industrial Wastes of Black Grapes (Vitis Vinifera L.), Hacettepe University, Graduate School of Health Sciences, Pharmacognosy Program, Master of Science Thesis, Ankara, ... -
Endocannabinoid System In The Airways
(2019)Cannabinoids and the mammalian endocannabinoid system is an important research area of interest and attracted many researchers because of their widespread biological effects. The significant immune-modulatory role of ... -
Endokrı̇n Bozucu Kı̇myasal Maddelere Kombı̇ne Maruzı̇yetı̇n Etkı̇lerinin Hepg2 Hücre Hattında Değerlendı̇rilmesı̇
(Sağlık Bilimleri Enstitüsü, 2018-04-24)Endocrine disruptors are synthetic or natural substances that disrupt the normal functioning of the body by mimicking or blocking hormones. They are suggested to affect many basic periods and characteristics like growth, ... -
Epigenetic And Genetic Changes Caused By Helicobacter Pylori And Their Roles In Gastric Carcinogenesis
(2019)Objective: Helicobacter pylori is a bacteria which colonizes in the gastric mucosa and it is one of the major infectious diseases throughout the world. There are findings pointing out that Helicobacter pylori can cause ... -
Erken Adölesan ve Adölesan Dönemde Ftalat Maruziyetinin Epigenetik Mekanizmalar ve Metabolik Profil Üzerindeki Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2021-07-08)Di (2-ethyl hexyl) phthalate (DEHP) is a chemical that has endocrine disrupting properties and is widely used in many customer products. Studies on DEHP show that toxicity specifically targets the male reproductive system. ...