Başlık için Eczacılık Meslek Bilimleri Bölümü listeleme
Toplam kayıt 341, listelenen: 81-100
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Çinko Oksit ve Bakır Oksit Nanoparçacıklarının in Vitro Sistemler Üzerindeki Toksik Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2017-09)Zinc oxide (ZnO) and copper oxide (CuO) NPs are commonly used metal nanoparticles with a high toxicity potential. However, information on toxicity mechanisms like other NPs, is limited. In this study, the possible ... -
Çocuklar ve ebeveynleri için kullanılacak ‘ilaç tedavisine uyunç’ ve ‘ilaca ilişkin hasta/hasta yakını yaklaşımı’ ölçeklerinin geliştirilmesi ve değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)It is known that the prescription rate of psychotropic drugs in adolescents is increasing, and medication adherence is lower in children and adolescents compared to adults. The effectiveness of psychotropic drugs is very ... -
Demans Hastalarında Tedaviye Uyunç Ve Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2019)Due to the increase in the elderly population in the world and in our country, the prevalence of dementia, which is one of the most common diseases in this age group, is rapidly increasing. Early diagnosis and treatment ... -
Deneysel Alerjik Astım Modelinde Mitokondri Hedefli Hidrojen Sülfür Donörü AP39 Tedavisinin Etkisinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2023)In this thesis, the effect of AP39, which is a mitochondria targeted slow releasing hydrogen sulfide (H2S) donor, were investigated in a mouse model of ovalbumin (OVA)-induced allergic asthma. In this model, experimental ... -
Deneysel Diyabet Modelinde Hipergliseminin Alzheimer Hastalığı ile İlişkili Proteinler Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2016-12)Diabetes mellitus (DM) which is one of the foremost health problems enhances the risk of Alzheimer’s disease (AD) although the molecular mechanisms behind this association remain unclear. In the present study, selective ... -
Design, Synthesis And In Vivo/In Vitro Screening Of Novel Chlorokojic Acid Derivatives
(Taylor & Francis Ltd, 2013)A series of novel Mannich bases of chlorokojic acid (2-chloromethyl-5-hydroxy-4H-pyran-4-one) were synthesized and their biological activities were investigated. Anticonvulsant activity results according to phase-I tests ... -
Detection Of Neopterin In Tear Samples
(Walter De Gruyter Gmbh, 2016)The main goal of the present study was to detect neopterin concentrations in human tear samples and to evaluate its potential correlation with serum neopterin levels. For this purpose, 20 systemically healthy volunteers ... -
Dibutil Ftalatın İnsan Akciğer Hücre Hattına Toksik Etkilerinin Değerlendirilmesi ve Askorbik Asit ve N-Asetilsisteinin Olası Koruyucu Etkileri
(Sağlık Bilimleri Enstitüsü, 2020)Endocrine disruptings are chemical substances which are generally produced by humans that disrupt the normal functioning of the body by imitating or blocking hormones. The mostly studied phthalate derivative is ... -
Dihidropiridin Türevlerinin Sentezi ve L-/T-Tipi Kalsiyum Kanal Bloke Edici Aktiviteleri
(Sağlık Bilimleri Enstitüsü, 2022-07-19)1,4- Dihydropyridines (DHPs) are the most well known inhibitors of L-type calcium channels and have important therapeutic value against cardiovascular diseases. Since they target different calcium channel subtypes, they ... -
Dinitroanilin Herbisitlerin Neden Olduğu Genotoksik Etkilerin ve Epigenetik Değişikliklerin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)It has been shown that genetic damage has an improtant role in the mechanisms of cancer and other chronic diseases that have been observed all over the world. Recently, theory about that epigenetic changes are also responsible ... -
Direct Enantiomeric Resolution Of Seventeen Racemic 1,4-Dihydropyridine-Based Hexahydroquinoline Derivatives By Hplc
(2019)1,4-Dihydropyridine (DHP) scaffold holds an outstanding position with its versatile pharmacological properties among all heterocyclic compounds. Although most of the commercially available DHPs are marketed as a racemic ... -
Discovery And Characterisation Of Dual Inhibitors Of Tryptophan 2,3-Dioxygenase (Tdo2) And Indoleamine 2,3-Dioxygenase 1 (Ido1) Using Virtual Screening
(2019)Cancers express tryptophan catabolising enzymes indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO2) to produce immunosuppressive tryptophan metabolites that undermine patients’ immune systems, leading ... -
Diyabet Hastalarında Pteridinlerin ve İlgili Yolakların Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-07-04)Gurcu, S., Evaluation of Pteridins and Related Pathways in Diabetes, Hacettepe University Institute of Health Sciences Ph.D. Thesis in Pharmaceutical Toxicology, Ankara, 2018. Pteridins are heterocyclic compounds that play ... -
Eczacılık Fakültesi Laboratuvar Çalışma Güvenliği El Kitabı
(Hacettepe Üniversitesi Yayınları, 2017)30.06.2012 tarihinden itibaren uygulamaya ilişkin çok sayıda yönetmelik ve tebliğ yayımlanmıştır. Bunlardan biri olan "Çalışanların İSG Eğitimlerinin Usul ve Esasları Hakkında Yönetmelik" gereğince, "az tehlikeli işyerleri" ... -
Eczane İçi Etkileşimlerin Konuşma Çözümlemesi Yoluyla İncelenmesi: Uzmanlık Bilgisi Gösterimi
(Sağlık Bilimleri Enstitüsü, 2018)Pharmaceutical care is defined as practitioner responsibility that optimizes the patient to use drug treatment as effectively and safely as possible under all circumstances. The importance of communication skills for ... -
Effects Of Cinnamic Acid On Complications Of Diabetes
(Tubitak Scientific & Technical Research Council Turkey, 2018)Background/aim: Diabetes mellitus (DM) is a major health problem worldwide. Cinnamic acid (CA) and its derivatives are synthesized in plants and increasing attention has been given to them in recent years due to the high ... -
Effects Of Developmental Exposure To Silver In Ionic And Nanoparticle Form: A Study In Rats
(2016)Background Evaluations of silver in both nanoparticle (Ag-NPs) and ionic forms indicate some adverse effects on living organisms, but little is known about their potential for developmental toxicity. In this study, ...