• 3,7-Dimethylguanine, A New Purine From A Philippine Sponge Zyzzya Fuliginosa 

      Taşdemir, Deniz; Mangalindan, Gina C; Concepcion, Gisela P; Harper, Mary Kay; Irelanda, Chris M (Pharmaceutical Soc Japan, 2001)
      A new purine 3,7-dimethylguanine (1) has been isolated from the marine sponge Zyzzya fuliginosa, along with the known metabolites. makaluvamines A, C, K (2-4), 4-hydroxyphenylacetic acid (5), methyl ester of 4-hydroxyphenylacetic ...
    • A Quadruped Study on Chitosan Microspheres Containing Atorvastatin Calcium: Preparation, Characterization, Quantification And In-Vivo Application 

      Eroglu, Hakan; Nemutlu, Emirhan; Turkoglu, Omer Faruk; Nacar, Osman; Bodur, Ebru; Sargon, Mustafa Fevzi; Beskonakli, Etem; Oner, Levent (Pharmaceutical Soc Japan, 2010)
      Atorvastatin is commonly used as a cholesterol lowering agent in patients. Recently, the neuroprotective effects of atorvastatin became the focus of many research studies. In this study, we have formulated chitosan ...
    • Anti-Inflammatory and Cytotoxic Activities of Five Veronica Species 

      Harput, US; Saraçoğlu, I; Inoue, M; Ogihara, Y (Pharmaceutical Soc Japan, 2002)
      Biological activities of five Veronica species (Scrophulariaceae), V. cymbalaria, V. hederifolia, V. pectinata var. glandulosa, V. persica and V. polita were studied for their anti-inflammatory and cytotoxic activities. ...
    • Antimetastatic Activity of Acteoside, A Phenylethanoid Glycoside 

      Ohno, T; Inoue, M; Ogihara, Y; Saracoglu, I (Pharmaceutical Soc Japan, 2002)
      We examined the antimetastatic effect of acteoside, a phenylethanoid glycoside widely distributed In the plant kingdom, on lung metastasis using a mouse model injected with B16 melanoma cells intravenously. Male C57BL/6 ...
    • Design And Characterization Of Nanocrystal Formulations Containing Ezetimibe 

      Gülsün, Tugba; Gürsoy, Reyhan Neslihan; Öner, Levent (Pharmaceutical Soc Japan, 2011)
      Ezetimibe is a lipid-lowering compound that selectively inhibits the absorption of cholesterol and related phytosterols from the intestine As ezetimibe is almost Insoluble in water, its bioavailability is too low to be ...
    • Iridoid Glucosides from Veronica Hederifolia 

      Harput, US; Saracoglu, I; Nagatsu, A; Ogihara, Y (Pharmaceutical Soc Japan, 2002)
      A new iridoid glucoside, urphoside A, and six known iridoid glucosides, pikuroside, aucubin, veronicoside, catalposide, amphicoside, and verminoside, were isolated from Veronica hederifolia together with a known megastigmane ...
    • Iridoid Glycosides from Globularia Davisiana 

      Calis, I; Kirmizibekmez, H; Tasdemir, D; Ireland, CM (Pharmaceutical Soc Japan, 2002)
      From the ethanolic extract of the aerial parts of Globularia davisiana. a new iridoid glycoside, davisioside (1), was isolated. Davisioside (1) comprises a rare iridoid aglycone structure with a saturated double bond between ...
    • Luddin Type Anthraquinone Glycosides from Putoria Calabrica 

      Calis, I; Tasdemir, D; Ireland, CM; Sticher, O (Pharmaceutical Soc Japan, 2002)
      Two new lucidin type anthraquinone glycosides, putorinoside A (1) and putorinoside B (2) were isolated from Putoria calabrica, in addition to two known anthraquinone glycosides, lucidin 3-O-beta-glucopyranoside (3) and ...
    • New Phenylethanoid Glycosides From Veronica Pectinata Var. Glandulosa And Their Free Radical Scavenging Activities 

      Saracoglu, I; Harput, US; Inoue, M; Ogihara, Y (Pharmaceutical Soc Japan, 2002)
      A known phenylethanoid glycoside, ehrenoside (1), was isolated together with three new phenylethanoid glycosides, verpectoside A (2), B (3) and C (4) from the aerial parts of Veronica pectinata var. glandulosa. On the basis ...
    • Phenylethanoid and Iridoid Glycosides from Veronica Persica 

      Harput, US; Saracoglu, I; Inoue, M; Ogihara, Y (Pharmaceutical Soc Japan, 2002)
      A new phenylethanoid glycoside, persicoside (1) and three known phenylethanoid glycosides, acteoside (2), isoacteoside (3) and lavandulifolioside (4) were isolated from the aerial parts of Veronica persica. On the basis ...
    • Sedative Effect of Centranthus Longiflorus Ssp Longiflorus in Rats and the Influence of Adrenalectomy on Its Effect 

      Suleyman, Halis; Guvenalp, Zuhal; Kizilkaya, Mehmet; Demirezer, L. Omur (Pharmaceutical Soc Japan, 2007)
      Sedative effect of the aqueous extract of Centranthus longiflorus ssp. longiflorus (Cle-1) on intact and adrenalectomized rats was investigated using a thiopental sleeping test to clarify the relationship of this effect ...
    • Structure-Activity Relationships Of Receptor Binding Of 1,4-Dihydropyridine Derivatives 

      Takahashi, Daiki; Oyunzul, LuvsandorJ; Onoue, Satoml; Ito, Yoshthlko; Uchida, Shinya; Simsek, Rahime; Gunduz, Miyase Gozde; Safak, Chiat; Yamada, Shizuo (Pharmaceutical Soc Japan, 2008)
      The present study was undertaken to investigate binding activity of synthesized 1,4-dihydropyridine (1,4-DHP) derivatives (Compounds 1-124) to 1,4-DHP calcium channel antagonist receptors in rat brain. Sixteen 1,4-DHP ...
    • Trojanosides I-K: New Cycloartane-Type Glycosides From The Aerial Parts Of Astragalus Trojanus 

      Bedir, E; Tatli, II; Calis, I; Khan, IA (Pharmaceutical Soc Japan, 2001)
      Three new cycloartane-type triterpene glycosides have been isolated from the aerial parts of Astragalus trojanus. The structures were established mainly by a combination of one- and two-dimensional NMR techniques ...
    • Two New Triterpene Saponins From Eryngium Campestre 

      Kartal, M; Mitaine-Offer, AC; Abu-Asaker, M; Miyamoto, T; Calis, I; Wagner, H; Lacaille-Dubois, MA (Pharmaceutical Soc Japan, 2005)
      Two new triterpene saponins, 3-O-beta-D-glucopyranosyl-(1 -> 2)-[alpha-L-rhamnopyranosyl-(1 -> 4)]-beta-D-glucuronopyranosyl-22-O-angeloyl-R1-barrigenol (1) and 3-O-beta-D-glucopyranosyl-(1 -> 2)-[alpha-L-rhamnopyranosyl(1 ...