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Dinitroanilin Herbisitlerin Neden Olduğu Genotoksik Etkilerin ve Epigenetik Değişikliklerin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)
It has been shown that genetic damage has an improtant role in the mechanisms of cancer and other chronic diseases that have been observed all over the world. Recently, theory about that epigenetic changes are also responsible ...
Üveit Patolojisinde Pteridin ve Kinürenin Yolaklarındaki Olası Değişimlerin Incelenmesi
(Sağlık Bilimleri Enstitüsü, 2014)
Uveitis is an intraocular inflammation affecting the highly vascularised uveal tissue. Early recognition and appropriate therapeutic intervention of uveitis is important since it may be associated with systemic disease and ...
Toxıcologıc Evaluatıon of Sılver Nanopartıcles
(Sağlık Bilimleri Enstitüsü, 2014)
Silver nanoparticles (Ag-NPs) are widely applied
in several products due to their unique physico-chemical properties as well
as bactericidal effects. The extensive application of Ag-NPs has raised
concerns about their ...
Bazı Yeni 2-Pirazolin Türevlerinin Sentezi ve Monoamin Oksidaz (Mao) İnhibitör Aktiviteleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2015)
In this study, forty two compounds which have 1-[2-(5-substituted-2-
benzoxazolinone-3-yl)acetyl]-3,5-disubstitutedphenyl-4,5-dihydro-1H-pyrazole
structure and nine compounds which have N’-(1,3-disubstitutedphenylallyl ...
Türkiye'de Piyasalarda Bulunan Bazı Curcuma Longa L. Rizom Ve Preparatları Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2012)
Curcuma longa L. rhizomes which are mainly used as spice and for medical purposes in Turkey, are rich in curcumin with (1E, 6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione structure. Three ungrounded rhizomes ...
Obez Çocuklarda Tiroid Işlev Bozuklukları ve Oksidan Antioksidan Statü Arasındaki Ilişkinin Metabolik Risk Etmenleri ile Birlikte Değerlendirilmesi.
(Sağlık Bilimleri Enstitüsü, 2013)
Obesity has been defined as “abnormal or excessive fat accumulation that may impair
health” by World Health Organization. Obesity is a chronic illness the prevalence of which
has increased in both developed and developing ...
Kronik Levetirasetam Uygulanan Normal ve Temporal Lob Epilepsi Modeli Oluşturulmuş Sıçanlarda Aromataz Ekspresyonu Değişiklikleri
(Sağlık Bilimleri Enstitüsü, 2015)
Temporal lobe epilepsy (TLE) model was generated at male Wistar rats by intraperitoneal (i.p.) injection of excitotoxic agent kainic acid (KA). This thesis work has been done as to investigate possible side-effects on ...
The Protectıve Role of Escıtalopram on Impared Hıppocampal Neuroplastıcıty Durıng Rem Deprıvatıon
(Sağlık Bilimleri Enstitüsü, 2013)
Sleep disorders are mostly associated with psychiatric problems like depression, anxiety disorders, etc. and are thought to be the underlying cause of cognitive deficits observed in these patients. It has been shown that ...
Bitkisel Kaynaklı Fenolik Yapıdaki Bileşiklerin Olası Sitotoksik ve Genotoksik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2014)
Free oxygen radicals
react with genetic material such as DNA, RNA and other cell macromolecules and
the cause oxidative damage. There is a worldwide increasing interest about
antioxidant compounds which could delay or ...
Bazı Gentiana Türleri Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2013)
The genus Gentiana (Gentianaceae) consists species
with important phytochemical properties and have been widely used in traditional
folk medicine. Iridoids, secoiridoids, C-glycosylflavones and xanthones are
considered ...