Başlık için Eczacılık Meslek Bilimleri Bölümü Tez Koleksiyonu listeleme
Toplam kayıt 144, listelenen: 7-26
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Antimikobakteriyel Aktivite Göstermesi Beklenen Bazı 2,3-Disübstitüe-5-Metil-4-Tiyazolidinon Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2019-09-07)Ekinci, A. S., Studies on Some 2,3-Disubstituted-5-Methyl-4-Thiazolidinone Derivatives Expected to Show Antimycobacterial Activity, Hacettepe University Graduate School of Health Sciences, MS Thesis in Pharmaceutical ... -
(Arilalkil)Azol Yapısında Yeni Oksim Ester Türevleri Üzerinde Çalışmalar: Sentez, Biyolojik Aktivite ve Moleküler Modelleme
(Sağlık Bilimleri Enstitüsü, 2018-01-22)In this study, a set of novel oxime esters in (arylalkyl)azole structure were designed based on azole antifungals, especially oxiconazole, and synthesized by the reaction of 1-(4-chlorophenyl)-2-(1H-imidazol/1H-1,2,4-tri ... -
Astragalus Isauricus Hub.-Mor. & Matthews Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2015)The genus Astaragalus is represented by 445 species 224 of which are endemic in Turkish flora. Astragalus species have been used to obtain “gum tragacanth” for many years. Also, numerous Astragalus species have been used ... -
Aşılarda Kullanılan Koruyucu ve Adjuvan Maddelerin Olası Toksik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)The World Health Organization defines vaccines as “pharmaceutical products that enable our immune system to recognize and fight pathogens such as viruses and bacteria and protect our body against the diseases caused by ... -
Azol Halkası Taşıyan COX İnhibitörlerinin Sentezi ve Antimikrobiyal Aktivitelerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2024-01)Nonsteroidal anti-inflammatory drugs (NSAIDs) are the group of drugs that show their effects by inhibiting cyclooxygenase (COX) enzymes and are frequently used in the treatment of pain and inflammation. In addition to these ... -
Bazı 2-(4-Sübstitüe)Fenil-5-Benziliden P-Sübstitüebenziliden-3-Fenilaminotiyazolidin-4-On Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2014)In this study, 2 new compunds having 3- (phenylamino)-2-[4-(1H-1,2,4-triazole/imidazolyl)phenyl]-1,3-thiazolidin-4-one (Compounds 1,2) and 9 new compounds having 5-(benzylidene/-psubstitutedbenzylidene)- 3-(phenylamin ... -
Bazı 2-Sübstitüe-1H-Benzimidazol Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2019)In this study, 12 (1 of registered in the literature) 2-(1H-benzo[d]imidazol-2-yl)-3-(4-(4-substitutedpiperazin-1- yl)phenyl)acrylonitrile (3a-l) and 3 2-(1H-benzo[d]imidazol-2-yl)-3-(4-(4- substitutedpiperazin-1-yl)p ... -
Bazı 2-Sübstitüe-4-(Furan-2-İlmetil)-6-MetilPiridazin-3(2H)-on Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2021-07-08)In this study, 16 new compounds, 2-[5-(furan-2-ylmethyl)-3-methyl-6-oxopyridazin-1(6H)-yl]-N-(aryl)acetamide (5a-j) and 4-(furan-2-ylmethyl)-6-methyl-2-[2-oxo-2-(4-arylpiperazin-1-yl)ethyl]pyridazin-3(2H)-one (6a-f), which ... -
Bazı 5-Kloro-2-benzoksazolinon Tiyosemikarbazit, 1,3,4-Tiyadiazol ve 1,2,4-Triazol-5-tiyon Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2018)In this study, nineteen new compounds which have 1-[2-(5-chloro-2-benzoxazolinone-3-yl)acetyl]-4-substitutedthiosemicarbazide, 3-[(5-chloro-2-benzoxazolinone-3-yl)methyl]-4-substituted-1H-1,2,4-triazole-5(4H)-thione, ... -
Bazı Benzotiyazol Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2018)In this study, fifteen 2-(4-substitutedphenyl)benzo[d]thiazole derivatives carrying substituted piperazine and azole moities at the 4 position of phenyl ring were synthesized, of which two had been reported in literature ... -
Bazı Gentiana Türleri Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2013)The genus Gentiana (Gentianaceae) consists species with important phytochemical properties and have been widely used in traditional folk medicine. Iridoids, secoiridoids, C-glycosylflavones and xanthones are considered ... -
Bazı Gentianella Türlerinin Fitokimyasal Analizleri ve Sekonder Metabolitlerinin BDNF (Beyin-Türevli Nörotrofik Faktör) Üzerindeki Etkileri
(Sağlık Bilimleri Enstitüsü, 2022)Gentianella Moench (Gentianaceae) species contain many secondary metabolites such as xanthones, flavonoids and terpenes. Flavonoids have been reported to contribute to the antidepressant effects of many medicinal plants ... -
Bazı Lamiaceae Familyası Bitkilerinin Osteoartrite Karşı Etkilerinin Matriks Metalloproteinaz-3 (Mmp-3) İnhibitör Etki Tayini ile Tespiti
(Sağlık Bilimleri Enstitüsü, 2021)Tahravi, L., Characterization of the Effects of Some Lamiaceae Family Plants Against Osteoarthritis by Matrix Metalloproteinase-3 (MMP-3) Inhibitory Effect Determination, Hacettepe University, Graduate School of Health ... -
Bazı N-(4-Sübstitüebenziliden)-5-Fenil-1,3,4-Tiyadiazol-2-Amin Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2018)In this study, 9 new compounds having 2-substituted-5-phenyl-1,3,4-thiadiazole structures were synthesized and their antifungal and antibacterial activities were evaluated. Target compounds were synthesized by reaction of ... -
Bazı Yeni 2-Pirazolin Türevlerinin Sentezi ve Monoamin Oksidaz (Mao) İnhibitör Aktiviteleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2015)In this study, forty two compounds which have 1-[2-(5-substituted-2- benzoxazolinone-3-yl)acetyl]-3,5-disubstitutedphenyl-4,5-dihydro-1H-pyrazole structure and nine compounds which have N’-(1,3-disubstitutedphenylallyl ... -
Bazı Yeni Tiyazolo[3,2-b]-1,2,4-triazol-6(5H)-on Türevlerinin Sentezi ve Sitotoksik Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021-07-13)In this study, thirty new hybrid chalcone derivatives, namely 2- substituted-5-benzylidentiazolo[3,2-b]-1,2,4-triazol-6(5H)-one (4a-6j) which is expected to show cytotoxic activity were synthesized. Titled compounds were ... -
Benzoksazolinon-hidrazon farmakoforu taşıyan dual etkili mao-aromataz inhibitörlerinin tasarımı ve sentezi: in siliko ve in vitro çalışmalar
(Sağlık Bilimleri Enstitüsü, 2022)Taşçi, N., Design and synthesis of dual MAO-Aromatase inhibitors containing benzoxazolinone-hydrazone pharmacophore: In silico and in vitro studies, Hacettepe University, Graduate School of Health Sciences PhD Thesis in ... -
Bisfenol Türevlerinin Oksidatif Stres Parametreleri Üzerine Etkilerinin HepG2 Hücrelerinde Karşılaştırmalı Olarak Değerlendirilmesi.
(Sağlık Bilimleri Enstitüsü, 2018)Bisphenols belong to a chemical group known as diphenylmethanes and widely used in the production of polycarbonate plastics, as basic chemicals in the resin coating of food and beverage tins. These substances are suggested ... -
Bitkisel Kaynaklı Fenolik Yapıdaki Bileşiklerin Olası Sitotoksik ve Genotoksik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2014)Free oxygen radicals react with genetic material such as DNA, RNA and other cell macromolecules and the cause oxidative damage. There is a worldwide increasing interest about antioxidant compounds which could delay or ...