• Inhibitory Effect Of The Methanolic Extract Of Verbascum Latisepalum Hub.-Mor. On Endothelium-Dependent Relaxation In Rat Thoracic Aorta 

      Bozkurt, T. Emrah; Tatli, I. Irem; Kahraman, Cigdem; Akdemir, Zeliha S.; Sahin-Erdemli, Inci (Walter De Gruyter Gmbh, 2014)
      The leaves and flowers of Verbascum species are used to treat respiratory disorders, haemorrhoids, rheumatic pain, and wounds as well as for the treatment of eczema and other types of inflammatory skin conditions in ...
    • Involvement of Rho Kinase and Protein Kinase C in Carbachol-Induced Calcium Sensitization in Beta-Escin Skinned Rat and Guinea-Pig Bladders 

      Durlu-Kandilci, N. Tugba; Brading, Alison F. (Wiley, 2006)
      1 The signal transduction pathways involved in carbachol (CCh)-induced calcium sensitization in beta-escin permeabilized rat and guinea-pig bladder smooth muscles were investigated and the results were compared with ...
    • Iridoid Glucosides from Veronica Hederifolia 

      Harput, US; Saracoglu, I; Nagatsu, A; Ogihara, Y (Pharmaceutical Soc Japan, 2002)
      A new iridoid glucoside, urphoside A, and six known iridoid glucosides, pikuroside, aucubin, veronicoside, catalposide, amphicoside, and verminoside, were isolated from Veronica hederifolia together with a known megastigmane ...
    • Iridoid Glycosides from Globularia Davisiana 

      Calis, I; Kirmizibekmez, H; Tasdemir, D; Ireland, CM (Pharmaceutical Soc Japan, 2002)
      From the ethanolic extract of the aerial parts of Globularia davisiana. a new iridoid glycoside, davisioside (1), was isolated. Davisioside (1) comprises a rare iridoid aglycone structure with a saturated double bond between ...
    • Iridoids from Galium Aparine 

      Deliorman, D; Calis, I; Ergun, F (Swets Zeitlinger Publishers, 2001)
      The isolation and UV, IR, H-1- and C-13-NMR data of asperulosidic acid, 10-deacetylasperulosidic acid from Galium aparine L. aerial parts are reported.
    • Isolation And Structure Elucidation Of Uncommon Secondary Metabolites From Cistus Salviifolius L. 

      Gurbuz, Perihan; Demirezer, Lutfiye Omur; Guvenalp, Zuhal; Kuruuzum-Uz, Ayse; Kazaz, Cavit (Acg Publications, 2015)
      To our knowledge this is the first report on the isolation of a flavonoid glycoside: quercetin 3-O-alpha-arabinopyranoside (5), two phenylbutanon glycosides: 4-(4'-O-[6''-O-galloyl-beta-galactopyranosyl]-3'-hydroxyphenyl ...
    • Luddin Type Anthraquinone Glycosides from Putoria Calabrica 

      Calis, I; Tasdemir, D; Ireland, CM; Sticher, O (Pharmaceutical Soc Japan, 2002)
      Two new lucidin type anthraquinone glycosides, putorinoside A (1) and putorinoside B (2) were isolated from Putoria calabrica, in addition to two known anthraquinone glycosides, lucidin 3-O-beta-glucopyranoside (3) and ...
    • New Phenylethanoid Glycosides From Veronica Pectinata Var. Glandulosa And Their Free Radical Scavenging Activities 

      Saracoglu, I; Harput, US; Inoue, M; Ogihara, Y (Pharmaceutical Soc Japan, 2002)
      A known phenylethanoid glycoside, ehrenoside (1), was isolated together with three new phenylethanoid glycosides, verpectoside A (2), B (3) and C (4) from the aerial parts of Veronica pectinata var. glandulosa. On the basis ...
    • New Secondary Metabolites From Quercus Coccifera L. 

      Sohretoglu, Didem; Kuruuzum-Uz, Ayse; Simon, Andras; Patocs, Tamas; Dekany, Miklos (Acg Publications, 2014)
      Three new secondary metabolites kermesoside (1), cocciferoside (2) and (-)-8-chlorocatechin (3), were isolated from the the stems with barks of Quercus coccifera along with five known phenolic compounds, 3-hydroxy-1-(4-h ...
    • Novel Triazolothiadiazines Act As Potent Anticancer Agents In Liver Cancer Cells Through Akt And Ask-1 Proteins 

      Aytac, Peri S.; Durmaz, Irem; Houston, Douglas R.; Cetin-Atalay, Rengul; Tozkoparan, Birsen (Pergamon-Elsevier Science Ltd, 2016)
      Newly designed triazolothiadiazines incorporating with structural motifs of nonsteroidal analgesic anti-inflammatory drugs were synthesized and screened for their bioactivity against epithelial cancer cells. Compounds with ...
    • Phenylacylated-Flavonoids from Peucedanum Chryseum 

      Gurbuz, Perihan; Baran, Merve Yuzbasioglu; Demirezer, Lutfiye Omur; Guvenalp, Zuhal; Kuruuzum-Uz, Ayse (Soc Brasileira Farmacognosia, 2018)
      Phytochemical investigation of the methanol extract of the aerial parts of Peucedanum chryseum (Boiss. & Heldr.) D.F.Chamb., Apiaceae, led to the isolation of a dihydrofuranochromone, cimifugin (1); a phloroacetophenone ...
    • Phenylethanoid and Iridoid Glycosides from Veronica Persica 

      Harput, US; Saracoglu, I; Inoue, M; Ogihara, Y (Pharmaceutical Soc Japan, 2002)
      A new phenylethanoid glycoside, persicoside (1) and three known phenylethanoid glycosides, acteoside (2), isoacteoside (3) and lavandulifolioside (4) were isolated from the aerial parts of Veronica persica. On the basis ...
    • Phenylpropanoids, Sesquiterpenoids And Flavonoids From Pimpinella Tragium Vill. Subsp Lithophila (Schischkin) Tutin 

      Ozbek, Hilal; Guvenalp, Zuhal; Kuruuzum-Uz, Ayse; Kazaz, Cavit; Demirezer, L. Omur (Acg Publications, 2016)
      A new sesquiterpenoid named germacradiene-6-O-(6'-O-acetyl)-beta-D-glucoside (1) and a new flavonol glycoside named rhamnetin-3-O-(2 ''-O-beta-D-glucopyranosyl)-beta-D-galactopyranoside (2), along with three known ...
    • Plant Cell Tissue And Organ Cultures In Terpenoids 

      Tatli, Irem I. (Bentham Science Publ, 2012)
      This chapter deals with the production of terpenoids, including pharmaceuticals and food additives through plant cell cultures, shoot cultures and root cultures obtained through biotechnological means. Plant cell and hairy ...
    • Polyphenolic Constituents And Antioxidant Potential Of Geranium Stepporum Davis 

      Sohretoglu, Didem; Sakar, Mahmut Koray; Sabuncuoglu, Suna Atasayar; Ozgunes, Hilal; Sterner, Olov (Acg Publications, 2011)
      The crude MeOH extract prepared from the aerial parts of G. stepporum and its EtOAc, n-BuOH, H(2)O subextracts were screened for their inhibitory activity on H(2)O(2)-induced lipid peroxidation in human red blood cells. ...
    • Potential Anticonvulsant Activity of Ethanol Extracts of Cichorium Intybus and Taraxacum Serotinum in Rats 

      Abdel-Rahman, Rehab F.; Soliman, Gamal A.; Yusufoglu, Hasan S.; Tatli-Cankaya, Irem; Alqasoumi, Saleh I.; Anul, Serap Arabci; Akaydin, Galip (Pharmacotherapy Group, 2015)
      Purpose: To evaluate the acticonvulsant activity of Cichorium intybus (C. intybus) and Taraxacum serotinum (T. serotinum) in maximal electroshock (MES), as well as pentylenetetrazole (PTZ)- and strychnine nitrate (STN) - ...
    • Radical Scavenging Effect Of Different Marine Sponges From Mediterranean Coasts 

      Aktas, Nihal; Genc, Yasin; Gozcelioglu, Bulent; Konuklugil, Belma; Harput, U. Sebnem (Acg Publications, 2013)
      To find new products reducing free radical damage is very important research area in recent pharmaceutical investigations. Considering this information, different marine sponges distributed in Mediterranean coasts of Turkey ...
    • Radical Scavenging Effects of Different Veronica Species 

      Harput, Ümmühan Şebnem; Genç, Yasin; Khan, Newaj; Saraçoğlu, İclal (Acg Publications, 2011)
      It is well known that the excessive production of reactive oxygen species is hazardous for living organisms and damages major cellular constituents such as DNA, lipid and protein. To find new products reducing free radical ...
    • Structure-Activity Relationships Of Receptor Binding Of 1,4-Dihydropyridine Derivatives 

      Takahashi, Daiki; Oyunzul, LuvsandorJ; Onoue, Satoml; Ito, Yoshthlko; Uchida, Shinya; Simsek, Rahime; Gunduz, Miyase Gozde; Safak, Chiat; Yamada, Shizuo (Pharmaceutical Soc Japan, 2008)
      The present study was undertaken to investigate binding activity of synthesized 1,4-dihydropyridine (1,4-DHP) derivatives (Compounds 1-124) to 1,4-DHP calcium channel antagonist receptors in rat brain. Sixteen 1,4-DHP ...
    • Synthesis and Antioxidant Properties of Novel Benzimidazole Derivatives 

      Ayhan-Kilcigil, G; Kus, C; Coban, T; Can-Eke, B; Iscan, M (Taylor & Francis Ltd, 2004)
      Some novel benzimidazole derivatives carrying thiosemicarbazide and triazole moieties at the N1 position were synthesized and their in vitro effects on rat liver microsomal NADPH-dependent lipid peroxidation (LP) levels ...