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dc.contributor.authorBilginer, Burcak
dc.contributor.authorNarin, Firat
dc.contributor.authorIsikay, Ilkay
dc.contributor.authorHanalioglu, Sahin
dc.contributor.authorBasar, Ibrahim
dc.contributor.author
dc.contributor.author
dc.contributor.author
dc.date.accessioned2020-12-07T10:53:14Z
dc.date.available2020-12-07T10:53:14Z
dc.date.issued2020
dc.identifier.citationIsikay I, Hanalioglu S, Narin F, Basar I, Bilginer B. Long-Term Outcomes of Pediatric Meningioma Surgery: Single Center Experience with 23 Patients. Turk Neurosurg. 2020;30(1):124-133. doi: 10.5137/1019-5149.JTN.27995-19.2. PMID: 31736038.
dc.identifier.urihttp://hdl.handle.net/11655/23160
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/31736038/
dc.identifier.urihttp://www.turkishneurosurgery.org.tr/abstract.php?id=2279
dc.identifier.urihttps://doi.org/10.5137/1019-5149.jtn.27995-19.2
dc.description.abstractAim: To evaluate the long-term outcomes and prognostic variables in a surgical cohort of pediatric meningiomas treated in a single institution. Material and methods: Medical records and follow-up notes of 23 pediatric patients aged < 18 years (12 male and 11 female; mean age on presentation, 13.1 ± 4.4 years) harboring 27 meningiomas operated between 1994 and 01/2019 at Hacettepe University Ihsan Dogramaci Children’s Hospital were evaluated. Results: One patient had neurofibromatosis (NF) type 1, and five patients had NF2. Tumors were most commonly located in the convexity (n=6) and parasagittal or falcine (n=6). Gross total resection was performed in 70.4% of cases. WHO grade I tumors accounted for 56% of all cases, whereas high-grade meningiomas accounted for 44% (33% grade II, 11% grade III). The mean follow-up duration was 10.3 ± 7.7 years. Three patients (13%) died during follow-up, and 76.2% of the patients had favorable outcome (Glasgow Outcome Scale > 3) during the last follow-up assessment. Ten patients (43.5%) had relapse. In univariate analysis, low histological grade (p=0.030) and gross total resection (p=0.024) were associated with favorable outcome. The 10-year overall survival rate was 86%. Conclusion: Meningiomas in the pediatric age group are surgically treatable tumors with fairly good outcomes. However, relapses are common even for low-grade tumors; therefore, long-term surveillance and aggressive treatment are needed.tr_TR
dc.language.isoentr_TR
dc.relation.isversionof10.5137/1019-5149.JTN.27995-19.2tr_TR
dc.rightsinfo:eu-repo/semantics/openAccesstr_TR
dc.rightsAttribution 4.0 United States
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectChildhood Meningioma Surgerytr_TR
dc.subjectRecurrence
dc.titleLong-Term Outcomes of Pediatric Meningioma Surgery: Single Center Experience with 23 Patientstr_TR
dc.typeinfo:eu-repo/semantics/articletr_TR
dc.relation.journalTurk Neurosurgtr_TR
dc.contributor.departmentBeyin ve Sinir Cerrahisitr_TR
dc.identifier.volume30tr_TR
dc.identifier.issue1tr_TR
dc.identifier.startpage124tr_TR
dc.identifier.endpage133tr_TR
dc.description.indexWoStr_TR
dc.fundingYoktr_TR


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